Version 2.78

69048-7 Immunologist review of results

Fully-Specified Name

Component
Immunologist review
Property
Imp
Time
Pt
System
XXX
Scale
Nar
Method

Additional Names

Short Name
Immunologist review
Display Name
Immunologist review [Interp]
Consumer Name Alpha Get Info
Immunologist review of test result

Basic Attributes

Class
MISC
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.75
Change Reason
Release 2.75: ORDER_OBS: submitter requested change;
Order vs. Observation
Both
Common Test Rank Get Info
4075

Member of these Panels

LOINC Long Common Name
96451-0 Alpha-1-Fetoprotein and Alpha-1-Fetoprotein.L3 panel - Serum or Plasma
90414-4 B-cell phenotyping panel - Blood
103575-7 Cat epithelium IgE panel - Serum or Plasma
102085-8 CNS Demyelinating Disease Panel - Serum or Plasma by Flow cytometry (FC)
104134-2 Dementia evaluation panel - Cerebral spinal fluid
104595-4 Dengue virus Ab.IgG and IgM and NS1 Ag panel - Serum or Plasma
104673-9 Diabetes mellitus type 1 autoimmune panel - Serum or Plasma
103574-0 Dog dander IgE panel - Serum or Plasma
96452-8 Hepatocellular carcinoma risk panel - Serum or Plasma
90416-9 Lymphocyte subset and B-cell phenotyping panel - Blood
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid
101417-4 Pediatric autoimmune central nervous system disorders evaluation panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Komm.Auto.AK
es-ES Spanish (Spain) Revisión del inmunólogo:Impresión/interpretación del estudio:Punto temporal:XXX:Narrativo:
es-MX Spanish (Mexico) Revisión de inmunólogo:Impresión / interpretación del estudio:Punto temporal:XXX:Narrativo:
fr-FR French (France) Validation des résultats d'immunologie:Interprétation:Ponctuel:Milieux divers:Résultat textuel:
it-IT Italian (Italy) Immunologo, esame:Imp:Pt:XXX:Nar:
Synonyms: Esame di immunologo Impressione/interpretazione di studio Miscellanea Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) beoordeling door immunoloog:interpretatie:moment:XXX:tekstueel:
ru-RU Russian (Russian Federation) Иммунолог рецензия:Впчт:ТчкВрм:XXX:Опис:
Synonyms: Впечатление/интерпретация исследования Описательный Точка во времени;Момент
tr-TR Turkish (Turkey) İmmünolog değerlendirmesi:İzlnm:Zmlı:XXX:Öykü:
zh-CN Chinese (China) 免疫学家审核:印象:时间点:XXX:叙述型:
Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 免疫学家回顾;免疫学家审阅;免疫学家审查;免疫学家评审 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 时刻;随机;随意;瞬间 杂项;杂项类;杂项试验

94356-3 Neuronal nuclear type 1 IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence

Part Descriptions

LP14163-7   Neuronal nuclear type 1
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable. Source: ARUP Laboratories, ANNA

Fully-Specified Name

Component
Neuronal nuclear type 1 Ab.IgG
Property
Titr
Time
Pt
System
CSF
Scale
SemiQn
Method
IF

Additional Names

Short Name
Hu1 IgG Titr CSF IF
Display Name
Neuronal nuclear type 1 IgG IF (CSF) [Titer]
Consumer Name Alpha Get Info
Neuronal nuclear type 1 IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.75
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid
94353-0 Myelopathy autoimmune Ab panel - Cerebral spinal fluid
94818-2 Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Anticuerpos Antineuronal nuclear tipo 1 IgG:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo:Inmunofluorescencia (IF)
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Tipo 1 nuclear neuronal Ab.IgG:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:Inmunofluorescencia (IF)
fr-CA French (Canada) Neuronal nucléaire de type 1, IgG:Titre:Temps ponctuel:LCR:SemiQn:Immunofluorescence
fr-FR French (France) Hu1 anticorps IgG:Titre:Ponctuel:Liquide céphalorachidien:Semi-Quantitatif:Immunofluorescence
it-IT Italian (Italy) Nucleare neuronale tipo 1 Ab.IgG:Titr:Pt:LCS:SemiQn:IF
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo
nl-NL Dutch (Netherlands) neuronaal nucleair type 1 As.IgG:titer:moment:liquor cerebrospinalis:semikwantitatief:immunofluorescentie
Synonyms: antistof; antilichaam IF soort
pl-PL Polish (Poland) Typ 1 neuronalny jądrowy Ab.IgG:miano:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:immunofluorescencja
Synonyms: IgG Przeciwciała do antygenów jądrowych neuronów typu 1 Przeciwciała IgG do antygenów jądrowych neuronów typu 1 Przeciwciała onkoneuronalne
zh-CN Chinese (China) 神经元细胞核 1 型 抗体.IgG:滴定度:时间点:脑脊液:半定量型:免疫荧光法
Synonyms: Ⅰ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 ANNA 1 Ab ANNA 1 抗体 ANNA 1;ANNA-1;Hu;Hu1;神经元核 1 型;神经元细胞核 1 型（Neuronal nuclear type 1，ANNA 1） ANNA-1 Ab ANNA-1 抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 FANA Hu Ab Hu 抗体 Hu1 Ab Hu1 抗体 I IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 免疫球蛋白 G 型 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 核;胞核 核心抗体IgG 核心抗原抗体.IgG 核心抗原抗体IgG 核心抗原抗体免疫荧光 核抗体.IgG 核抗体IgG 核抗原抗体.IgG 核抗原抗体IgG 神经元性;神经元的 神经元核 神经元核 1 型 Ab 神经元核 1 型抗体 神经元细胞核 1 型 Ab 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
{titer} Example UCUM Units

77202-0 Laboratory comment [Text] in Report Narrative

Term Description

Narrative text comments from the laboratory that are included on the result report. These comments will not include the actual test result(s).
Source: Regenstrief LOINC

Fully-Specified Name

Component
Laboratory comment
Property
Txt
Time
Pt
System
Report
Scale
Nar
Method

Additional Names

Short Name
Laboratory comment Report
Display Name
Laboratory comment Nar (Report)
Consumer Name Alpha Get Info
Laboratory comment, Report

Basic Attributes

Class
MISC
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
444

Member of these Panels

LOINC Long Common Name
98249-6 Cancer pathology panel - Endometrial cancer specimen
101919-9 Iohexol disappearance panel - Urine and Serum or Plasma
102114-6 Natural cannabinoids panel - Urine
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid
101417-4 Pediatric autoimmune central nervous system disorders evaluation panel - Serum or Plasma
106054-0 Primary biliary cholangitis comprehensive Ab panel - Serum or Plasma
96403-1 Renal clearance and Renal plasma flow panel - Urine and Serum or Plasma
98412-0 Retrograde ejaculation evaluation panel - Urine

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Comentario de Laboratorio:Texto:Punto temporal:Informe:Narrativo:
es-MX Spanish (Mexico) Comentario de laboratorio:Texto:Punto temporal:Informe:Narrativo:
fr-FR French (France) Commentaire du laboratoire:Texte:Ponctuel:Rapport:Résultat textuel:
fr-CA French (Canada) Laboratoire Commentaire:texte:Temps ponctuel:Rapport:Narratif:
Synonyms: #REF!
it-IT Italian (Italy) Laboratorio, commento:Txt:Pt:Referto:Nar:
Synonyms: Commento di laboratorio Miscellanea Punto nel tempo (episodio) Testo
nl-NL Dutch (Netherlands) laboratorium opmerking:tekst:moment:verslag:tekstueel:
pl-PL Polish (Poland) Komentarz laboratoryjny:tekst:punkt w czasie:raport:opisowy:
tr-TR Turkish (Turkey) Laboratuvar önerisi:Metin:Zmlı:Rapor:Öykü:
zh-CN Chinese (China) 实验室注释:文本型属性:时间点:报告:叙述型:
Synonyms: 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 备注 备注;评论;注解;说明;评语 实验室（检验科、检验室、化验室）注释（备注、注解、评论、说明、意见） 意见 报道;汇报;调查报告;报表;报导 文本;文本型;文本属性 时刻;随机;随意;瞬间 杂项;杂项类;杂项试验 检验科;化验室;化验科 注解 短评 解说 解释 评定 评注 评论 评语 说明

94286-2 Contactin-associated protein 2 IgG Ab [Presence] in Cerebral spinal fluid by Cell binding immunofluorescent assay

Part Descriptions

LP230270-3   Contactin-associated protein 2
Contactin-associated protein 2 (CASPR2) is present in the axons of the granule neurons of the cerebellum and the juxtaparanodal region of myelinated axons. Increased titers of CASPR2 antibodies were first discovered in patients with Morvan's syndrome. Symptoms of Morvan's syndrome include neuromyotonia, insomnia, autonomic dysfunction and neuropathic pain. Though CASPR2 antibodies have been found in 10% of patients with idiopathic cerebellar ataxia, no specific disease has been attributed to patients with the rare occurrence of positive antibodies for CASPR2 with cerebellar involvement. PMID: 25846566 Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
Contactin-associated protein 2 Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
CASPR2 IgG CSF Ql CBA IFA
Display Name
Contactin-associated protein 2 IgG Cell binding immunofluorescent assay Ql (CSF)
Consumer Name Alpha Get Info
Contactin-associated protein 2 IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.69
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Member of these Groups Get Info

LOINC Group Group Name
LG50959-2 Contactin-associated protein 2 Ab.IgG|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Proteína 2 Ab.IgG asociada a contactina:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Ensayo inmunofluorescente de unión a células
es-ES Spanish (Spain) Proteína 2 asociada a contactina IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
fr-FR French (France) CASPR2 anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence CBA
it-IT Italian (Italy) Proteina 2 Contactin-associata Ab.IgG:PrThr:Pt:LCS:Ord:CBA IFA
Synonyms: anticorpi IgG anticorpo CNTNAP2 Fluorescenza indiretta degli anticorpi (IFA) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
zh-CN Chinese (China) 接触蛋白关联蛋白 2 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:CBA IFA
Synonyms: Ⅱ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CASPR2;接触蛋白相关蛋白 2;接触素关联蛋白 2;接触素相关蛋白 2 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 II PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 关联的 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 有联系的 相关的 细胞结合分析免疫荧光法;CBA IFA 法 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 间接荧光抗体 间接荧光抗体试验

82989-5 Dipeptidyl aminopeptidase-like protein 6 IgG Ab [Presence] in Cerebral spinal fluid by Immunofluorescence

Part Descriptions

LP230267-9   Dipeptidyl aminopeptidase-like protein 6
Dipeptidyl aminopeptidase-like protein 6 (DPPX) is a regulatory subunit of neuronal Kv4.2 potassium channel and is encoded by the DPPX gene. PMID: 25320100 DPPX is a type II membrane protein that binds to specific voltage-gated potassium channels and changes their biophysical characteristics. Alterations in the DPPX gene are associated with amyotrophic lateral sclerosis with idiopathic ventricular fibrillation. [NCBI Gene ID: 1804] IgG to DPPX is a biomarker for a frequently multifocal neurological disorder that develops insidiously, can be severe, responds to immunotherapy and is likely to relapse. Clinical symptoms associated with postive DPPX IgG include encephalopathy (with cortical, cerebellar or brainstem manifestations), myelopathy and autonomic dysfunction. PMID: 25320100 Source: Regenstrief LOINC

Fully-Specified Name

Component
Dipeptidyl aminopeptidase-like protein 6 Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IF

Additional Names

Short Name
DPPX IgG CSF Ql IF
Display Name
Dipeptidyl aminopeptidase-like protein 6 IgG IF Ql (CSF)
Consumer Name Alpha Get Info
Dipeptidyl aminopeptidase-like protein 6 IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid
94353-0 Myelopathy autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Member of these Groups Get Info

LOINC Group Group Name
LG50957-6 Dipeptidyl aminopeptidase-like protein 6 Ab.IgG|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Proteina 6 tipo Dipeptidil aminopeptidasa IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Proteína similar a la dipeptidil aminopeptidasa 6 Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunofluorescencia (IF)
fr-FR French (France) DPPX anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence
it-IT Italian (Italy) Dipeptidil aminopeptidasi-like proteina 6 Ab.IgG:PrThr:Pt:LCS:Ord:IF
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) dipeptidyl-aminopeptidase-achtig proteïne 6 As.IgG:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam dipeptidyl-aminopeptidase-like IF
zh-CN Chinese (China) 二肽氨基肽酶样蛋白 6 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:免疫荧光法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 二肽氨肽酶样蛋白 6;DPP6;DPPX;DPP VI;VF2;MRD33;DPL1;二肽氨基肽酶相关蛋白;二肽氨基肽酶 6;二肽氨基肽酶 IV-样蛋白;二肽氨基肽酶 VI;Dipeptidyl aminopeptidase-related protein;Dipeptidyl peptidase 6;Dipeptidyl peptidase IV-like protein;Dipeptidyl peptidase VI 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 氨肽酶 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

93426-5 GABABR IgG Ab [Presence] in Cerebral spinal fluid by Cell binding immunofluorescent assay

Part Descriptions

LP230268-7   Gamma aminobutyrate B receptor
Gamma aminobutyrate B receptor (GABABR) is a neural surface cell synaptic antigen and is associated with limbic encephalitis and orolingual dyskinesias. Symptoms of limbic encephalitis include delirium, mood change, memory and personality disturbance and focal seizures of mesial temporal type with or without secondary generalization. Antibodies against GABABR indicate the possibility of undiscovered small cell lung cancer or other neuroendocrine neoplasia. PMCID: PMC3726118 Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
Gamma aminobutyrate B receptor Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
GABABR IgG CSF Ql CBA IFA
Display Name
GABABR IgG Cell binding immunofluorescent assay Ql (CSF)
Consumer Name Alpha Get Info
GABABR IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.69
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Member of these Groups Get Info

LOINC Group Group Name
LG50933-7 Gamma aminobutyrate B receptor Ab.IgG|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Receptor B de Gamma aminobutirato IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
es-MX Spanish (Mexico) Receptor de gamma aminobutirato B Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Ensayo inmunofluorescente de unión a células
fr-FR French (France) Gamma aminobutyrate récepteur B anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence CBA
it-IT Italian (Italy) Gamma-amminobutirrato B, recettore Ab.IgG:PrThr:Pt:LCS:Ord:CBA IFA
Synonyms: anticorpi IgG anticorpo Fluorescenza indiretta degli anticorpi (IFA) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Recettore GABA Sierologia (anticorpi e la maggior parte degli ant
zh-CN Chinese (China) Gamma 氨基丁酸 B 受体 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:CBA IFA
Synonyms: 4-氨基丁酸;GABA;Gamma 氨基丁酸（Gamma aminobutyric acid，GABA）;Gamma-氨基丁酸;G-氨基丁酸;γ氨基丁酸;γ-氨基丁酸;哌啶酸 Ab.IgG;IgG;抗体 IgG Ab;自身抗体 B 型 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 γ氨基丁酸 B 受体;γ-氨基丁酸 B 受体;GABA-B 受体;GABA-B receptor;GABA-B-R 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 氨基-n-丁酸 氨基丁酸盐 氨基丁酸酯 细胞结合分析免疫荧光法;CBA IFA 法 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 间接荧光抗体 间接荧光抗体试验

94359-7 Glutamate decarboxylase 65 IgG+IgM Ab [Moles/volume] in Cerebral spinal fluid by Immunoassay

Part Descriptions

LP18489-2   Glutamate decarboxylase 65
Glutamate decarboxylase 65 (GAD65) antibody is useful to diagnose insulin dependent diabetes mellitus (IDDM, Type I diabetes), to assess the risk for developing IDDM, to predict the onset of IDDM and the risk of developing related endocrine disorders such as thyroiditis. Before clinical onset, Type I diabetes is characterized by lymphocytic infiltration of the islet cells and by circulating autoantibodies against a variety of islet cell antigens including GAD-65, IA-2 (a tyrosine phosphatase-like protein), and insulin (IAA). GAD has two isoforms, GAD65 and GAD67, which are highly homologous but found in distinct subsets of patients. PMID: 7532143 GAD65 antibodies are specific to patients with insulin-dependent diabetes. The presence of GAD antibodies in a patient recently diagnosed with diabetes indicates a high risk of requiring insulin within three years. PMID: 11114103 GAD67 is important to the maturation of perisomatic innervation.( http://www.sciencedirect.com/science/article/pii/S0896627307003728) GAD65 are also associated with paraneoplastic neurologic syndrome (PNS) which is an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. In addition, the different PNS antibodies are associated with certain cancers and can assist in identifying where an unknown tumor is located. PMID: 22412264 Glutamic acid decarboxylase 65 antibody are associated with stiff person syndrome, cerebellar ataxia encephalitis and other neurological diseases. PMID: 22405456 Source: Regenstrief LOINC

Fully-Specified Name

Component
Glutamate decarboxylase 65 Ab.IgG+IgM
Property
SCnc
Time
Pt
System
CSF
Scale
Qn
Method
IA

Additional Names

Short Name
GAD65 IgG+IgM CSF IA-sCnc
Display Name
Glutamate decarboxylase 65 IgG+IgM IA (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
Glutamate decarboxylase 65 IgG+IgM, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid
94353-0 Myelopathy autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Glutamato decarboxilasa 65 IgG+IgM:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Glutamato descarboxilasa 65 IgG + IgM:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Glutamaadi dekarboksülaasi 65 vastased antikehad.IgG+IgM:SCnc:Pt:CSF:Qn:IA
Synonyms: Aine kontsentratsioon Immuunglobuliin G Immuunglobuliin M Juhuslik Kvantitatiivne Liikvor
fr-FR French (France) Glutamate décarboxylase 65 anticorps IgG+IgM:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:Immunoanalyse
fr-CA French (Canada) Glutamate décarboxylase 65, IgG+IgM:Concentration de substance:Temps ponctuel:LCR:Quantitatif:IA
fr-BE French (Belgium) Glutamate décarboxylase 65 Anticorps.IgG+IgM:Concentration de substance:Temps ponctuel:LCR:Quantitatif:IA
Synonyms: Anticorps
it-IT Italian (Italy) Glutammato decarbossilasi 65 Ab.IgG+IgM:SCnc:Pt:LCS:Qn:IA
Synonyms: anticorpi IgG anticorpi IgG e IgM Anticorpi IgG+IgM anticorpo Concentrazione di Sostanza GAD65 Immunoassay Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) glutamaatdecarboxylase 65 As.IgG + IgM:mol/volume:moment:liquor cerebrospinalis:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
ru-RU Russian (Russian Federation) Глутаматдекарбоксилаза 65 Ат.IgG+IgM:МолКонц:ТчкВрм:ЦСЖ:Колич:IA
Synonyms: Антитело Количественный Молярность;Молярная объёмная концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Glutamat dekarboksilaz 65 Ab.IgG+IgM:SubKons:Zmlı:BOS:Kant:İA
Synonyms: Ak Ak.IgG Ak.IgG+IgM İmmünölçüm, immünoassay
zh-CN Chinese (China) 谷氨酸脱羧酶-65 抗体.IgG+IgM:物质的量浓度:时间点:脑脊液:定量型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab.IgG+IgM;IgG+IgM;抗体 IgG+抗体 IgM Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 GAD65;GAD-65;谷氨酸脱羧酶 65;谷氨酸脱羧酶 65（Glutamate Decarboxylase 65，GAD65，Glutamic acid decarboxylase-65，GAD-65） GADA Glu 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 免疫球蛋白 M 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抗体.IgG & IgM;抗体.IgG+IgM 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 谷氨酸脱羧酶 65 Ab 谷氨酸脱羧酶 65 抗体 谷氨酸脱羧酶-65 Ab 麸胺酸去羧酶;麸胺酸去羧基酶;麸氨酸去羧基酶;GAD

Example Units

Unit Source
nmol/L Example UCUM Units

94360-5 Glial fibrillary acidic protein alpha subunit IgG Ab [Presence] in Cerebral spinal fluid by Immunofluorescence

Part Descriptions

LP411550-9   Glial fibrillary acidic protein.alpha subunit Ab.IgG
Glial fibrillary acidic protein (GFAP) antibody is a biomarker for immune inflammation. GFAP IgG autoantibody binds to GFAPα, and is found in serum and cerebrospinal fluid (CSF) of indiviuals with GFAP astrocytopathy. GFAP antibodies are detectable by immunofluorescence (IF), cell-based assay (CBA) and western blot. GFAP astrocytopathy often overlaps with other autoimmune diseases, making diagnosis challenging due to the coexisting neural autoantibodies. PMID: 30568655 Source: Regenstrief LOINC

Fully-Specified Name

Component
Glial fibrillary acidic protein.alpha subunit Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IF

Additional Names

Short Name
GFAP alpha IgG CSF Ql IF
Display Name
Glial fibrillary acidic protein alpha subunit IgG IF Ql (CSF)
Consumer Name Alpha Get Info
Glial fibrillary acidic protein alpha subunit IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94353-0 Myelopathy autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Member of these Groups Get Info

LOINC Group Group Name
LG51003-8 Glial fibrillary acidic protein.alpha subunit Ab.IgG|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Subunidad alfa de la proteína ácida fibrilar glial IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Proteína ácida fibrilar glial subunidad alfa IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunofluorescencia (IF)
fr-FR French (France) GFAP alpha anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence
it-IT Italian (Italy) Proteina acida fibrillare gliale.alfa Ab.IgG:PrThr:Pt:LCS:Ord:IF
Synonyms: anticorpi IgG anticorpo GFAP Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Subunità alfa
zh-CN Chinese (China) 神经胶质纤维酸性蛋白.alpha 亚单位 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:免疫荧光法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 GFAP;神经胶质纤维酸性蛋白;glial fibrillary acidic protein IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 PGH Alpha 亚单位;PGH α亚单位;α亚单位;垂体糖蛋白;垂体糖蛋白类 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 α 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 神经胶质纤维酸性蛋白.alpha 亚单位（alpha 亚基、α-亚基、α-亚单位、α亚基、α亚单位）;神经胶质纤维酸性蛋白.α亚基;神经胶质纤维酸性蛋白.α亚单位;GFAP-α 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 阿尔法

94288-8 Leucine-rich glioma-inactivated protein 1 IgG Ab [Presence] in Cerebral spinal fluid by Cell binding immunofluorescent assay

Part Descriptions

LP230269-5   Leucine-rich glioma-inactivated protein 1
Leucine-rich glioma-inactivated protein 1 (LGI1) is part of a group of antigens that have target antibodies that bind to neuronal cell surface or synaptic proteins but are not associated with a malignancy. The ensuing encephalitis has been designated neuronal surface antibody syndrome or autoimmune synaptic encephalitis. LGI1 antibodies have been associated with encephalitis that responds well to treatment and has a good expected outcome. PMID: 25520958 Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
Leucine-rich glioma-inactivated protein 1 Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
LGI1 IgG CSF Ql CBA IFA
Display Name
Leucine-rich glioma-inactivated protein 1 IgG Cell binding immunofluorescent assay Ql (CSF)
Consumer Name Alpha Get Info
Leucine-rich glioma-inactivated protein 1 IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.69
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Member of these Groups Get Info

LOINC Group Group Name
LG50961-8 Leucine-rich glioma-inactivated protein 1 Ab.IgG|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Proteína 1 inactivada del glioma rica en leucina IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
es-MX Spanish (Mexico) Proteína inactivada por glioma rica en leucina 1 Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Ensayo inmunofluorescente de unión a células
fr-FR French (France) LGI1 anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence CBA
it-IT Italian (Italy) Proteina 1 glioma-inattivata ricca di leucina Ab.IgG:PrThr:Pt:LCS:Ord:CBA IFA
Synonyms: anticorpi IgG anticorpo Fluorescenza indiretta degli anticorpi (IFA) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
zh-CN Chinese (China) 富亮氨酸胶质瘤失活蛋白 1 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:CBA IFA
Synonyms: Ⅰ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 I Leu;异己氨酸;白氨酸 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 富亮氨酸胶质瘤失活1蛋白;LGI1 时刻;随机;随意;瞬间 细胞结合分析免疫荧光法;CBA IFA 法 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 间接荧光抗体 间接荧光抗体试验

94361-3 Metabotropic glutamate receptor 1 IgG Ab [Presence] in Cerebral spinal fluid by Immunofluorescence

Part Descriptions

LP411535-0   Metabotropic glutamate receptor 1
Antibodies against metabotropic glutamate receptor type 1 (mGluR1) are associated with a rare autoimmune encephalitis. The primary manifestation is cerebellar ataxia, and other symptoms include dysarthria, cognitive impairment, and abnormalities in the sense of taste. mGluR1 is a cell-surface receptor expressed predominantly in cerebellar Purkinje cell dendrites that plays a major role in coordination and cerebellar motor learning. Other areas in which mGluR1 is expressed include the olfactory bulb, thalamus, and hippocampus. PMID: 31205493 Source: Regenstrief LOINC

Fully-Specified Name

Component
Metabotropic glutamate receptor 1 Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IF

Additional Names

Short Name
mGluR1 IgG CSF Ql IF
Display Name
Metabotropic glutamate receptor 1 IgG IF Ql (CSF)
Consumer Name Alpha Get Info
Metabotropic glutamate receptor 1 IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid
94353-0 Myelopathy autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Member of these Groups Get Info

LOINC Group Group Name
LG50966-7 Metabotropic glutamate receptor 1 Ab.IgG|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Receptor de glutamato metabotrópico 1 IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Receptor metabotrópico de glutamato 1 Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunofluorescencia (IF)
fr-FR French (France) mGluR1 anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence
it-IT Italian (Italy) Metabotropico del glutammato, recettore 1 Ab.IgG:PrThr:Pt:LCS:Ord:IF
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Recettore 1 metabotropico del glutammato Sierologia (anticorpi e la maggior parte degli ant
pl-PL Polish (Poland) Glutaminergiczny receptor metabotropowy typu I Ab.IgG:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:immunofluorescencja
Synonyms: IgG Przeciwciała IgG onkoneuronalne anty mGluR1 Przeciwciała onkoneuronalne anty mGluR1
zh-CN Chinese (China) 代谢型谷氨酸受体 1 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:免疫荧光法
Synonyms: Ⅰ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Glu I IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 mGluR1 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

93502-3 NMDAR subunit 1 IgG Ab [Presence] in Cerebral spinal fluid by Cell binding immunofluorescent assay

Part Descriptions

LP229977-6   N-methyl-D-aspartate receptor subunit 1
N-methyl-D-aspartate receptor 1 (NMDAR1) is subunit of NMDA receptors and belongs to the glutamate receptor channel superfamily. It is encoded by the GRIN1 (Glutamate [NMDA] receptor subunit zeta-1) gene located on chromosome 9q34.3.[UniProt: Q05586] Glutamate receptors are highly permeable to calcium and important for nervous system functioning. NMDAR1 antibodies are detected in patients with paraneoplastic syndromes, autoimmune encephalopathies and related conditions. Identification of specific antineuronal autoantibodies may direct evaluation for underlying malignancy. Characterization of autoantibody specificity may allow syndromic classification and assist in diagnosis and management. Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
N-methyl-D-aspartate receptor subunit 1 Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
NMDAR1 IgG CSF Ql CBA IFA
Display Name
NMDAR subunit 1 IgG Cell binding immunofluorescent assay Ql (CSF)
Consumer Name Alpha Get Info
NMDAR subunit 1 IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.69
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Subunidad 1 del receptor de N-metil-D-aspartato Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Ensayo inmunofluorescente de unión a células
es-ES Spanish (Spain) Subunidad 1 del receptor de N-metil-D-aspartato (NMDAR-1) IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
fr-FR French (France) NMDAR1 anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence CBA
it-IT Italian (Italy) N-metil-D-aspartato, subunità 1 recettore Ab.IgG:PrThr:Pt:LCS:Ord:CBA IFA
Synonyms: anticorpi IgG anticorpo Fluorescenza indiretta degli anticorpi (IFA) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Recettore dell''N-metil-D-aspartato; NMDAR Sierologia (anticorpi e la maggior parte degli ant Subunità 1 del recettore dell''N-metil-D-aspartato
zh-CN Chinese (China) N-甲基-D-天冬氨酸受体亚单位 1 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:CBA IFA
Synonyms: Ⅰ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 Asp;天冬氨酸;门冬氨酸 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 I N 型 N-甲基-D-天冬氨酸受体亚基 1;N-甲基-D-天门冬氨酸受体亚单位 1;N-甲基-D-天门冬氨酸受体亚基 1;NMDAR 亚单位 1;NMDAR 亚基 1 N-甲基-D-天门冬氨酸（Asp、天冬氨酸、门冬氨酸）受体 Rh;Rhesus;恒河猴;猕猴;罗猴 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 细胞结合分析免疫荧光法;CBA IFA 法 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 间接荧光抗体 间接荧光抗体试验

46718-3 Aquaporin 4 water channel IgG Ab [Presence] in Cerebral spinal fluid

Part Descriptions

LP39188-5   Aquaporin 4 water channel Ab.IgG
The water channel aquaporin 4 (AQP4) receptor regulates the water homeostasis in the central nervous system (CNS). Autoantibodies to the AQP4 receptor bind to the receptor and cause neuromyelitis optica (NMO) which is an idiopathic, severe, demyelinating disease of the CNS that primarily affects the optic nerve and spinal cord. Before the discovery of the AQP4 receptor antibody NMO was often misdiagnosed as a variant of multiple sclerosis (MS). With improved clinical laboratory tests and distinct immunological and pathological attributes the two diseases are less often confused. Distinguishing MS and NMO is especially important because they have different treatments. Treatment for NMO includes corticosteroids and plasmapheresis; typical medications used to treat MS, such as beta-interferon and glatiramer acetate are not effective against NMO. During the disease process, the aquaporin 4 receptor antibody binds to the aquaporin 4 receptor initiating the activation of complement, inflammatory demyelination and necrosis. Eighty to ninety percent of patients with NMO experience recurrent episodes of optic neuritis and myelitis. Many patients with NMO also have other autoimmune diseases including thyroiditis, systemic lupus erythematosus
and Sjogren's syndrome. PMID: 17706564 Detection of APQ4-IgG is indicative of a relapsing disease. Immediate treatment with immunosuppressive drugs reduces the frequency and disability of future attacks. [http://labmed.ucsf.edu/labmanual/db/dataall/tests/1424.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Aquaporin 4 water channel Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method

Additional Names

Short Name
AQP4 H2O channel IgG CSF Ql
Display Name
Aquaporin 4 water channel IgG Ql (CSF)
Consumer Name Alpha Get Info
Aquaporin 4 water channel IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.73
Change Reason
Release 2.67: COMPONENT: Updated "receptor" to "water channel" per current scientific nomenclature; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
8092

Member of these Panels

LOINC Long Common Name
94353-0 Myelopathy autoimmune Ab panel - Cerebral spinal fluid
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid
101417-4 Pediatric autoimmune central nervous system disorders evaluation panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG50124-3 Aquaporin 4 water channel Ab.IgG|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Aquaporin-4-Antikörper IgG ql. /L
es-MX Spanish (Mexico) Acuaporina 4 canal de agua Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:
es-ES Spanish (Spain) Receptor de Acuaporina 4 IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:
et-EE Estonian (Estonia) Akvaporiin 4 retseptor antikehad.IgG:PrThr:Pt:CSF:Ord:
Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Liikvor
fr-BE French (Belgium) Récepteur Aquaporin 4 Anticorps. IgG:PrThr:Temps ponctuel:LCR:Ordinal:
Synonyms: Anticorps
fr-FR French (France) Aquaporine 4 récepteur anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:
fr-CA French (Canada) Récepteur Aquaporin 4, IgG:Présence-Seuil:Temps ponctuel:LCR:Ordinal:
it-IT Italian (Italy) Acquaporina 4, canale idrico Ab.IgG:PrThr:Pt:LCS:Ord:
Synonyms: anticorpi IgG anticorpo Canale idrico dell''acquaporina 4 Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) aquaporine 4 waterkanaal As.IgG:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Neuromyelitis optica Ac.IgG:ACnc:Pt:LCR:Ord:
Synonyms: ; NMO; Devic's disease; Immune globulin G; Immunoglobulin G; Arbitrary concentration; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Аквапорина 4 рецепторы Ат.IgG:PrThr:ТчкВрм:ЦСЖ:Пор:
Synonyms: Антитело Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Akuaporin 4 reseptörü Ab.IgG:MevcEşik:Zmlı:BOS:Srl:
Synonyms: Ak Ak.IgG Mevcut
uk-UA Ukrainian (Ukraine) Аквапорин-4 водний канал Антитіла. IgG:Наявність або Поріг:МоментЧасу:Спинномозкова рідина:Порядково:
Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; AQP4; AQP4 H2O channel; Autoantibodies; Autoantibody; Cerebral spinal fluid; Cerebrospinal Fl; Devic's disease; Immune globulin G; Immunoglobulin G; Neuromyelitis optica; NMO; NMO spectrum disorders; NMOSD; Opticospinal multiple sclerosis; Ordinal; Point in time; PR; QL; Qual; Qualitative; Random; Screen; Serology; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid; Water channel aquaporin-4
zh-CN Chinese (China) 水通道蛋白 4 受体 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Devic 氏综合征 IgG Devic 综合征 IgG Devic氏综合征 Ab.IgG Devic氏综合征抗体.IgG Devic综合征 Ab.IgG Devic综合征抗体.IgG H2O NMO Ab.IgG NMO 抗体.IgG 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 视神经脊髓炎 Ab.IgG 视神经脊髓炎 IgG

94362-1 PCA-Tr IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence

Part Descriptions

LP31709-6   Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264 Source: Regenstrief LOINC

Fully-Specified Name

Component
Purkinje cell cytoplasmic type Tr Ab.IgG
Property
Titr
Time
Pt
System
CSF
Scale
SemiQn
Method
IF

Additional Names

Short Name
PCA-Tr IgG Titr CSF IF
Display Name
PCA-Tr IgG IF (CSF) [Titer]
Consumer Name Alpha Get Info
PCA-Tr IgG antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.75
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid
94353-0 Myelopathy autoimmune Ab panel - Cerebral spinal fluid
94818-2 Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence
101416-6 Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Células de Purkinje tipo Tr IgG:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo:Inmunofluorescencia (IF)
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Citoplasma de células de Purkinje tipo Tr Ab.IgG:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:Inmunofluorescencia (IF)
fr-FR French (France) Tr anticorps IgG:Titre:Ponctuel:Liquide céphalorachidien:Semi-Quantitatif:Immunofluorescence
fr-CA French (Canada) Cellules de Purkinje cytoplasmique type Tr, IgG:Titre:Temps ponctuel:LCR:SemiQn:Immunofluorescence
it-IT Italian (Italy) Cellule di Purkinje tipo Tr Ab.IgG:Titr:Pt:LCS:SemiQn:IF
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo
nl-NL Dutch (Netherlands) purkinjecellen type Tr As.IgG:titer:moment:liquor cerebrospinalis:semikwantitatief:immunofluorescentie
Synonyms: antistof; antilichaam IF soort
pl-PL Polish (Poland) Cytoplazmatyczne typu Tr komórek Purkinjego Ab.IgG:miano:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:immunofluorescencja
Synonyms: IgG Przeciwciała IgG do cytoplazmy komórek Purkinjego typu Tr Przeciwciała typu Tr do cytoplazmy komórki Purkinjego
zh-CN Chinese (China) 浦肯雅细胞胞浆 Tr 型 抗体.IgG:滴定度:时间点:脑脊液:半定量型:免疫荧光法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 Purkinje 细胞 Tr 型 Ab Purkinje 细胞 Tr 型抗体 Tr 型 Purkinje 细胞 Ab Tr 型 Purkinje 细胞抗体 TR 型朴金耶细胞 Ab TR 型朴金耶细胞抗体 TR 型浦肯雅细胞 Ab TR 型浦肯雅细胞抗体 TR 型浦金埃细胞 Ab TR 型浦金埃细胞抗体 免疫球蛋白 G 型 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 朴金耶细胞 Tr 型 Ab 朴金耶细胞 Tr 型抗体 浦肯雅细胞 Tr 型 Ab 浦肯雅细胞 Tr 型抗体 浦金埃细胞 Tr 型 Ab 浦金埃细胞 Tr 型抗体 细胞浆的;细胞质;细胞质的;胞浆;胞浆的 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
{titer} Example UCUM Units