101568-4
Thyroglobulin and Thyroglobulin Ab panel - Tissue fine needle aspirate
Active
53919-7 Thyroglobulin Ab [Units/volume] in Tissue fine needle aspirate
Part Descriptions
LP14697-4 Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Thyroglobulin (Wikipedia)
LP14697-4 Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. PMID: 9543128
Source: Regenstrief LOINC
LP39996-1 Thyroglobulin Ab
Circulating immunoglobulins directed against thyroglobulin are commonly present in patients with autoimmune (Hashimoto) thyroiditis and, to a lesser extent, Graves disease. Thyroglobulin is a 660-kd protein precursor of thyroid hormones. Thyroglobulin antibodies are present in the sera of approximately 70% of patients with autoimmune thyroiditis. The principal use of the test is to confirm that a patient's diffuse goiter and/or hypothyroidism is due to autoimmune thyroiditis. The test may also help distinguish Graves disease from toxic nodular goiter. Although thyroglobulin antibodies are present less often than thyroid microsomal antibodies (eg, thyroid peroxidase antibodies, anti-TPO) in patients with autoimmune thyroid diseases, screening fro both immunoglobulins increases diagnostic sensitivity. Thyroglobulin antibodies may be detected in individuals without clinically significant thyroid disease. They do not define the patient's thyroid functional status.
Source: Quest Diagnostics Inc., Thyroglobulin antibodies
Fully-Specified Name
- Component
- Thyroglobulin Ab
- Property
- ACnc
- Time
- Pt
- System
- Tiss.FNA
- Scale
- Qn
- Method
Additional Names
- Short Name
- Thyroglob Ab Tiss FNA-aCnc
- Display Name
- Thyroglobulin Ab Qn (Tissue fine needle aspirate)
- Consumer Name Alpha Get Info
- Thyroglobulin antibody, Tissue fine needle aspirate
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.26
- Last Updated
- Version 2.70
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
101568-4 | Thyroglobulin and Thyroglobulin Ab panel - Tissue fine needle aspirate |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Tiroglobulina Anticuerpos: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Tiroglobulina Ab: |
fr-CA | French (Canada) | Thyroglobuline, Ac: |
fr-BE | French (Belgium) | Thyroglobuline Ac: Synonyms: Anticorps hTG |
fr-FR | French (France) | Thyroglobuline anticorps: |
it-IT | Italian (Italy) | Tireoglobulina Ab: Synonyms: Agoaspirato tessuto anticorpo Concentrazione Arbitraria Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Tessuto & |
nl-NL | Dutch (Netherlands) | thyreoglobuline As: Synonyms: antistof; |
pt-BR | Portuguese (Brazil) | Tireoglobulina Ac: Synonyms: AntiTiroglob; |
ru-RU | Russian (Russian Federation) | Тиреоглобулин Ат: Synonyms: Антитело Количественный Произвольная концентрация Ткань аспирационная биопсия тонкой иглой Ткань и мазки Точка во времени; |
tr-TR | Turkish (Turkey) | Tiroglobulin Ab: Synonyms: Ak Doku.İİA |
zh-CN | Chinese (China) | 甲状腺球蛋白 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
[IU]/mL | Example UCUM Units |
53922-1 Thyroglobulin [Mass/volume] in Tissue fine needle aspirate
Part Descriptions
LP14697-4 Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Thyroglobulin (Wikipedia)
LP14697-4 Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. PMID: 9543128
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Thyroglobulin
- Property
- MCnc
- Time
- Pt
- System
- Tiss.FNA
- Scale
- Qn
- Method
Additional Names
- Short Name
- Thyroglob Tiss FNA-mCnc
- Display Name
- Thyroglobulin (Tissue fine needle aspirate) [Mass/Vol]
- Consumer Name Alpha Get Info
- Thyroglobulin, Tissue fine needle aspirate
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.26
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 6358
Member of these Panels
LOINC | Long Common Name |
---|---|
101568-4 | Thyroglobulin and Thyroglobulin Ab panel - Tissue fine needle aspirate |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG51139-0 | Thyroglobulin| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-MX | Spanish (Mexico) | Tiroglobulina: |
es-ES | Spanish (Spain) | Tiroglobulina: Synonyms: Cuantitativo |
fr-BE | French (Belgium) | Thyroglobuline: Synonyms: hTG |
fr-FR | French (France) | Thyroglobuline: |
fr-CA | French (Canada) | Thyroglobuline: |
it-IT | Italian (Italy) | Tireoglobulina: Synonyms: Agoaspirato tessuto Chimica Concentrazione di Massa Punto nel tempo (episodio) Tessuto & |
nl-NL | Dutch (Netherlands) | thyreoglobuline: |
pt-BR | Portuguese (Brazil) | Tireoglobulina: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Тиреоглобулин: Synonyms: Количественный Массовая концентрация Ткань аспирационная биопсия тонкой иглой Ткань и мазки Точка во времени; |
tr-TR | Turkish (Turkey) | Tiroglobulin: Synonyms: Doku.İİA |
uk-UA | Ukrainian (Ukraine) | Тиреоглобулін: Synonyms: Chemistry; |
zh-CN | Chinese (China) | 甲状腺球蛋白: Synonyms: FNA TG; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
ng/mL | REGENSTRIEF |