Version 2.78

Part Descriptions

LP14441-7   Cells.CD3+CD4+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively. Source: Regenstrief Help

LP14441-7   Cells.CD3+CD4+
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc). Source: Regenstrief Help

LP14443-3   CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides Source: Regenstrief LOINC

Fully-Specified Name

Component
Cells.CD3+CD4+^after stimulation with SARS-CoV-2 Nucleocapsid peptide
Property
NCnc
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Short Name
CD3+CD4+ Cells p COVID NuclCap # Bld
Display Name
CD3+CD4+ (T4 helper) cells after stimulation with SARS-CoV-2 Nucleocapsid peptide (Bld) [#/Vol]
Consumer Name Alpha Get Info
CD3+CD4+ (T4 Helper) Cells after stimulation with SARS-CoV-2 Nucleocapsid peptide, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.75
Last Updated
Version 2.75
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Células CD3+CD4+^Tras la estimulación con el péptido Nucleocápside del SARS-CoV-2:Concentración de número:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
fr-FR French (France) CD3+CD4+ après stimulation par la nucléocapside SARS-CoV-2:Nombre/Volume:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Cellule.CD3+CD4+^dopo stimolazione con peptide Nucleocapside di SARS-CoV-2:NCnc:Pt:Sangue:Qn:
Synonyms: Cellule CD3 Cellule CD3+CD4+ Cellule CD3-CD4+ Concentrazione Numerica Microbiologia Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) cellen.CD3+CD4+^na stimulatie met SARS-CoV-2 nucleocapsidepeptide:aantal/volume:moment:bloed:kwantitatief:
Synonyms: SARS-coronavirus 2; ''Severe acute respiratory syndrome''-coronavirus 2
zh-CN Chinese (China) 细胞.CD3+CD4+^采用 SARS 冠状病毒 2 核衣壳肽刺激之后:计数型浓度:时间点:全血:定量型:
Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ CD3+CD4+细胞 CD3-CD4+细胞 CD3细胞 II L3T4 Leu3 Leu-3 Leu4;Leu-4;T3 T4 T-4 W3/25 兴奋 刺激作用 单位体积内的数量或计数;数量型浓度(单位体积);数量或计数型浓度(计数/体积);数量或计数型浓度(单位体积);计数型浓度(单位体积) 发现于辅助 T-细胞；微弱表达于单核细胞。与相关。一些成熟 T-细胞肿瘤，包括大多数情况下的 T-细胞慢性淋巴细胞白血病/前淋巴细胞白血病、外周 T-细胞淋巴瘤、成人 T-细胞白血病/淋巴瘤以及 Sézary 综合征（T 细胞红皮病）/蕈样肉芽肿（mycosis fungoides）。 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 缩氨酸 血;血液 诱导 T 细胞 诱导性 T 细胞 辅助 T 细胞 辅助诱导 T 细胞 辅助诱导物 T 细胞 采用 SARS 冠状病毒 2 核衣壳（核壳、病毒粒子、壳体核）肽刺激之后;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典

Example Units

Unit Source
{cells}/uL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=101644-3