Version 2.78

74520-8 Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

Fully-Specified Name

Component
Complement alternate pathway AH50 actual/normal
Property
RelACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
AH50 Act/Nor Ser IA
Display Name
Complement alternate pathway AH50 actual/normal IA (S) [Rel units/Vol]
Consumer Name Alpha Get Info
Complement Alternate Pathway AH50 actual/normal, Blood

Basic Attributes

Class
HEM/BC
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.73
Change Reason
Updated term to align with existing complement activity terms and clarify that findings are based on actual/normal results.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Observation
Common Test Rank Get Info
7463

Member of these Panels

LOINC Long Common Name
74519-0 Complement activity panel - Serum
101922-3 Eculizumab Monitoring Panel
101923-1 Ravulizumab Monitoring Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Complemento total vía alternativa AH50 actual/normal:Concentración arbitraria relativa:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Complementar la vía alternativa AH50 real / normal:Concentración relativa arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Komplemendi alternatiivse tee aktiivsus AH50 tegelik/normaalne:RelACnc:Pt:S:Qn:IA
Synonyms: Juhuslik Kvantitatiivne Seerum Suhteline kokkuleppeline kontsentratsioon
fr-CA French (Canada) Complément voie alterne AH50, Mesuré/normal:Concentration relative arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-BE French (Belgium) Complément voie alterne AP50 Mesuré/normal:Concentration relative arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
Synonyms: Mesuré/normal
fr-FR French (France) Complément alternative pathway AH50 Patient (%):Activité arbitraire relative:Ponctuel:Sérum:Numérique:Immunoanalyse
it-IT Italian (Italy) Complemento totale, via alternativa AH50 effettivo/normale:RelACnc:Pt:Siero:Qn:IA
Synonyms: Concentrazine Arbitraria Relativa Ematologia (coagulazione) conta differenziale Immunoassay Punto nel tempo (episodio) Siero Via alternativa AH50 del complemento totale
nl-NL Dutch (Netherlands) complement totaal alternatieve route AH50 gemeten/normaal:relatieve eenheid/volume:moment:serum:kwantitatief:immunoassay
Synonyms: gemeten/normaal IA
pt-BR Portuguese (Brazil) Complemento funcional atividade caminho alternativo::Pt:Soro:Qn:Imunoensaio
ru-RU Russian (Russian Federation) Комплемент общий альтернативный путь AH50 актуальный/нормальный:ОтнПроизвКонц:ТчкВрм:Сыв:Колич:IA
Synonyms: Количественный Относительная произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Kompleman total alternatif yol AH50 gerçek/normal:GörSçKons:Zmlı:Ser:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 补体备用途径活性 AH50 实际的/正常的:相对任意型浓度:时间点:血清:定量型:免疫测定法
Synonyms: 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实测值 实测值/正常值;实际/正常;实际值/正常值;实际测定值/正常值 实测的 实际值 对照 对照标准 对照物 对照的 时刻;随机;随意;瞬间 正常的 相对任意浓度;相对型任意浓度;相对人工型浓度 血液学/细胞计数;血液学与细胞计数 补体总备用途径活性 AH50

Example Units

Unit Source
% Example UCUM Units

90240-3 Eculizumab [Mass/volume] in Serum

Part Descriptions

LP268095-9   Eculizumab
Eculizumab is monoclonal antibody that binds to the C5 complement component and is used to treat atypical hemolytic uremic syndrome (aHUS). aHUS is characterized by hemolytic anemia that leads to the presence of schistocytes, thrombocytopenia, renal damage, and other organ system impairment. aHUS is caused by a rare genetic mutation that interferes with the regulation of the complement system and leads to thrombotic microangiopathy (TMA). Prior to the development of eculizumab, the only treatment for aHUS was plasmapheresis, which did not stop progressive organ impairment. Eculizumab is an extremely expensive but effective therapy against aHUS and provides good outcomes and improved quality of life for patients with aHUS. Eculizumab has also been found to increase the possibility for the repair of renal damage. PMID: 27766045Measurement of eculizumab in serum is used for monitoring and therapy optimization. Source: Regenstrief LOINC

Fully-Specified Name

Component
Eculizumab
Property
MCnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
Eculizumab Ser-mCnc
Display Name
Eculizumab (S) [Mass/Vol]
Consumer Name Alpha Get Info
Eculizumab, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
101922-3 Eculizumab Monitoring Panel

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Eculizumab:Concentración de masa:Punto temporal:Suero:Cuantitativo:
es-ES Spanish (Spain) Eculizumab:Concentración de masa:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
fr-FR French (France) Éculizumab:Masse/Volume:Ponctuel:Sérum:Numérique:
it-IT Italian (Italy) Eculizumab:MCnc:Pt:Siero:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Siero
zh-CN Chinese (China) 依库珠单抗:质量浓度:时间点:血清:定量型:
Synonyms: 依库组单抗;艾库组单抗;依库丽单抗 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

Unit Source
ug/mL Example UCUM Units