103721-7
West Nile virus RNA [Presence] in Blood by NAA with non-probe detection
Active
Part Description
LP28423-9 West Nile virus
The West Nile Virus (WNV) is an arbovirus that was first identified in the West Nile District of Uganda in 1937. In the fall of 1999, the National Veterinary Services Laboratory (NVLS) isolated WNV in a dead crow in New York City.(http://www.who.int/mediacentre/factsheets/fs354/en/) Over the following ten years, WNV spread throughout the United States, Canada, Mexico and the Carribbean. WNV is usually transmitted through the bite of the Culex mosquito, but can also be spread in blood transfusions, organ transplants, breast milk, intrauterine exposure and laboratory-acquired infections. Birds are the preferred host of WNV, and the American robin is an important amplifier host since it develops enough virus in its serum to infect feeding mosquitoes. Though most infections with WNV are subclinical for humans, between 2005 and 2009 there were 12,975 people infected with WNV, of which 35% had severe cases of neuroinvasive disease and 496 people died. For individuals who are 70 years of age or older, infection with WNV has a 15-29% fatality rate. For infants and immunocompromised patients infected with WNV, the fatality rate is even higher. Diagnosis of WNV is based on clinical symptoms and antibody titers. The IgM antibody-capture enzyme-linked immunosorbent assay (MAC-ELISA) is the key method used to diagnosis WNV in clinical settings. Antibody titers to WNV NS5 are detectable long-term in vivo and can be used to distinguish past infection with WNV from current infection. RNA is usually undetectable in serum after 13.2 days, but on rare occasions, has been found in serum beyond 40 days. Treatment of infection with WNV is mostly supportive. There are no FDA-approved drugs or vaccines available. PMID: 12089283 PMID: 23034323
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- West Nile virus RNA
- Property
- PrThr
- Time
- Pt
- System
- Bld
- Scale
- Ord
- Method
- Non-probe.amp.tar
Additional Names
- Short Name
- WNV RNA Bld Ql NAA+non-probe
- Display Name
- West Nile virus RNA NAA+non-probe Ql (Bld)
- Consumer Name Alpha Get Info
- West Nile virus, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.77
- Last Updated
- Version 2.77
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
101344-0 | Acute febrile illness global pathogens panel - Blood by NAA with non-probe detection |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG32768-0 | West Nile virus |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Virus Nilo Occidental RNA: |
fr-CA | French (Canada) | Virus du Nil occidental ARN: |
it-IT | Italian (Italy) | Nilo occidentale, virus RNA: Synonyms: Amplificazione target non basata su sonda Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sangue Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus del Nilo occidentale |
zh-CN | Chinese (China) | 西尼罗河病毒 RNA: Synonyms: WNV RNA WNV; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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