Version 2.78

Part Description

LP14668-5   HMB-45
HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for Human Melanoma Black. It is used in anatomic pathology as a marker for such tumors.

The antibody was generated to an extract of melanoma. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. The antibody also reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes.

HMB-45 is nonreactive with almost all non-melanoma human malignancies, with the exception of rare tumors showing evidence of melanogenesis (e.g., pigmented schwannoma, clear cell sarcoma) or tumors associated with tuberous sclerosis complex (angiomyolipoma and lymphangiomyoma). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
HMB-45 Ag
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Immune stain

Additional Names

Short Name
HMB45 Ag Tiss Ql ImStn
Display Name
HMB-45 Ag Immune stain Ql (Tiss)
Consumer Name Alpha Get Info
HMB-45 antigen, Tissue

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 1.0i
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
15284

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) antígeno HMB-45:concentración arbitraria:punto en el tiempo:tejido, no especificado:ordinal:tinción inmunológica
es-ES Spanish (Spain) HMB-45 Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
es-MX Spanish (Mexico) HMB-45 Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
et-EE Estonian (Estonia) HMB-45 antigeen:PrThr:Pt:Tis:Ord:Immuunvärv
Synonyms: Järgarvuline Juhuslik Kude
fr-CA French (Canada) HMB-45, Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FR French (France) HMB-45 antigène:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
fr-BE French (Belgium) HMB-45 Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
Synonyms: Antigène Coloration. Méthode mmunologique
it-IT Italian (Italy) HMB-45, Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
Synonyms: Patologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) HMB-45 항원:임의농도:검사시점:조직:순위척도:면역염색
nl-NL Dutch (Netherlands) HMB-45 Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
Synonyms: antigeen
pt-BR Portuguese (Brazil) HMB-45 Ag:ACnc:Pt:Tecido:Ord:Imunocoloração
Synonyms: ; HMB45; Arbitrary concentration; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; ImStn; Immunostain; Immunohistochemical stain; IHC; Antigen; Antigens; Imun; Imune; Imm; PATHOLOGY
ru-RU Russian (Russian Federation) HMB-45 Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) HMB-45 Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama
Synonyms: Antijen Mevcut
zh-CN Chinese (China) HMB-45 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
Synonyms: Ag HMB-45 Ag 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染法 染色方法 染色法 着色 着色方法 着色法

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=10487-7