10506-4
Peanut agglutinin Ag [Presence] in Tissue by Immune stain
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Part Descriptions
LP14687-5 Peanut agglutinin
Lectin purified from peanuts (ARACHIS HYPOGAEA). It binds to poorly differentiated cells and terminally differentiated cells and is used in cell separation techniques.
Source: National Library of Medicine, MeSH 2006
LP14687-5 Peanut agglutinin
Peanut agglutinin (PNA) is plant lectin protein derived from the fruits of Arachis hypogaea. Peanut agglutinin may also be referred to as Arachis hypogaea lectin. Lectins recognise and bind particular sugar sequences in carbohydrates; peanut agglutinin binds the carbohydrate sequence Gal-β(1-3)-GalNAc. The name "peanut agglutinin" originates from its ability to stick together (agglutinate) cells, such as neuramidase-treated erythrocytes, which have glycoproteins or glycolipids on their surface which include the Gal-β(1-3)-GalNAc carbohydrate sequence.
Because peanut agglutinin specifically binds a particular carbohydrate sequence it finds use in a range of methods for cell biology and biochemistry. For example in PNA-affinity chromatography the binding specificity of peanut agglutinin is used to isolate glycosylated molecules which have the sugar sequence Gal-β(1-3)-GalNAc. Peanut agglutinin activity is inhibited by lactose and galactose which compete for the binding site.
Other uses include Potent anti-T cell activity, distinguishing between human lymphocyte subsets, tumour tissue determination for transitional mucosa malignancies, identification of mammalian-infective metacyclic promastigote Leishmania major parasites from other life cycle forms also found in the sandfly host.
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Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- Peanut agglutinin Ag
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- Immune stain
Additional Names
- Short Name
- PNA Ag Tiss Ql ImStn
- Display Name
- Peanut agglutinin Ag Immune stain Ql (Tiss)
- Consumer Name Alpha Get Info
- Peanut Agglutinin antigen, Tissue
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 1.0i
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | [antígeno de ] de aglutinina de maní [Ag]: |
es-ES | Spanish (Spain) | Aglutinina de cacahuete Antígeno: |
es-MX | Spanish (Mexico) | Aglutinina de maní: |
et-EE | Estonian (Estonia) | Maapähkli aglutiniin antigeen: Synonyms: Järgarvuline Juhuslik Kude |
fr-CA | French (Canada) | Agglutinine d'arachide, Ag: |
fr-FR | French (France) | Arachide lectine antigène: |
fr-BE | French (Belgium) | Agglutinine d'arachide Ag: Synonyms: Antigène Coloration. Méthode mmunologique |
it-IT | Italian (Italy) | Arachidi, agglutinina, Ag: Synonyms: Agglutinina delle arachidi Patologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & |
ko-KR | Korean (Korea, Republic Of) | 땅콩 응집소 항원: |
nl-NL | Dutch (Netherlands) | pinda-agglutinine Ag: Synonyms: antigeen |
pl-PL | Polish (Poland) | Aglutynina orzechów ziemnych Ag: Synonyms: Aglutynina zawarta w orzechach ziemnych Antygen aglutyniny orzecha ziemnego barwnik immunologiczny |
pt-BR | Portuguese (Brazil) | Aglutinina do Amendoim Ag: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Арахиса агглютинин Аг: Synonyms: Порядковый Ткань и мазки Точка во времени; |
tr-TR | Turkish (Turkey) | Yerfıstığı aglütinin Ag: Synonyms: Antijen Mevcut |
zh-CN | Chinese (China) | 花生凝集素 抗原: Synonyms: Ag PNA Ag PNA; |
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