105285-1
Neutrophil Ab screen panel - Serum or Plasma
Active
105288-5 Neutrophil membrane Ab [Interpretation] in Serum or Plasma Narrative
Part Descriptions
LP231983-0 Neutrophil membrane Ab
Antineutrophil membrane antibodies are antibodies that bind to antigens on the surface of neutrophils. Several specific antigens have been identified, but the IgG Fc receptor type 3b is the primary target. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary AIN there is no association with another pathology. Primary AIN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary AIN usually occurs following a systemic haematologic disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell transplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neutrophil membrane Ab
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nar
- Method
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78 (ADD)
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 105285-1 | Neutrophil Ab screen panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Μεμβράνη ουδετερόφιλου Αντίσωμα: Synonyms: Imp |
| es-ES | Spanish (Spain) | Membrana neutrófila Anticuerpos: |
| fr-FR | French (France) | Membrane des polynucléaires neutrophiles anticorps: |
| it-IT | Italian (Italy) | Membrana neutrofili Ab: Synonyms: anticorpo Impressione/interpretazione di studio Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | neutrofiel membraan As: Synonyms: antistof; |
| zh-CN | Chinese (China) | 嗜中性粒细胞膜 抗体: Synonyms: Ab; |
105287-7 Neutrophil membrane Ab [Presence] in Serum or Plasma by Agglutination
Part Descriptions
LP231983-0 Neutrophil membrane Ab
Antineutrophil membrane antibodies are antibodies that bind to antigens on the surface of neutrophils. Several specific antigens have been identified, but the IgG Fc receptor type 3b is the primary target. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary AIN there is no association with another pathology. Primary AIN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary AIN usually occurs following a systemic haematologic disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell transplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neutrophil membrane Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
- Aggl
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78 (ADD)
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 105285-1 | Neutrophil Ab screen panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51665-4 | Neutrophil membrane Ab| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Μεμβράνη ουδετερόφιλου Αντίσωμα: Synonyms: PrThr |
| es-ES | Spanish (Spain) | Membrana neutrófila Anticuerpos: |
| fr-FR | French (France) | Membrane des polynucléaires neutrophiles anticorps: |
| it-IT | Italian (Italy) | Membrana neutrofili Ab: Synonyms: Agglutinazione anticorpo Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | neutrofiel membraan As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Neutrofil błona Ab: Synonyms: Błona neutrofila Neutrofil |
| zh-CN | Chinese (China) | 嗜中性粒细胞膜 抗体: Synonyms: Ab; |
105286-9 Neutrophil membrane Ab [Presence] in Serum or Plasma by Flow cytometry (FC)
Part Descriptions
LP231983-0 Neutrophil membrane Ab
Antineutrophil membrane antibodies are antibodies that bind to antigens on the surface of neutrophils. Several specific antigens have been identified, but the IgG Fc receptor type 3b is the primary target. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary AIN there is no association with another pathology. Primary AIN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary AIN usually occurs following a systemic haematologic disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell transplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neutrophil membrane Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
- Flow cytometry
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78 (ADD)
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 105285-1 | Neutrophil Ab screen panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51665-4 | Neutrophil membrane Ab| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Μεμβράνη ουδετερόφιλου Αντίσωμα: Synonyms: PrThr |
| es-ES | Spanish (Spain) | Membrana neutrófila Anticuerpos: |
| fr-FR | French (France) | Membrane des polynucléaires neutrophiles anticorps: |
| it-IT | Italian (Italy) | Membrana neutrofili Ab: Synonyms: anticorpo Citometria a flusso (FC) Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | neutrofiel membraan As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Neutrofil błona Ab: Synonyms: Błona neutrofila Neutrofil |
| zh-CN | Chinese (China) | 嗜中性粒细胞膜 抗体: Synonyms: Ab; |