Version 2.78

Part Description

LP231983-0   Neutrophil membrane Ab
Antineutrophil membrane antibodies are antibodies that bind to antigens on the surface of neutrophils. Several specific antigens have been identified, but the IgG Fc receptor type 3b is the primary target. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary AIN there is no association with another pathology. Primary AIN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary AIN usually occurs following a systemic haematologic disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell transplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350 Source: Regenstrief LOINC

Fully-Specified Name

Component
Neutrophil membrane Ab
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
Flow cytometry

Additional Names

Long Common Name
Neutrophil membrane Ab [Presence] in Serum or Plasma by Flow cytometry (FC)
Short Name
Neutrophil membrane Ab SerPl Ql FC
Display Name
Neutrophil membrane Ab FC Ql
Consumer Name Alpha Get Info
Neutrophil membrane antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
105285-1 Neutrophil Ab screen panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG51665-4 Neutrophil membrane Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Membrana neutrófila Anticuerpos:PrThr:Punto temporal:Suero o Plasma:Ord:Citometria de flujo (FC)
it-IT Italian (Italy) Membrana neutrofili Ab:PrThr:Pt:Siero/Plasma:Ord:Citometria a flusso
Synonyms: anticorpo Citometria a flusso (FC) Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) neutrofiel membraan As:aanwezigheid:moment:serum of plasma:ordinaal:flowcytometrie
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Neutrofil błona Ab:granica wykrywalności:punkt w czasie:surowica lub osocze:półilościowy:cytometria przepływowa (FC)
Synonyms: Błona neutrofila Neutrofil
zh-CN Chinese (China) 嗜中性粒细胞膜 抗体:存在情况或阈值:时间点:血清/血浆:序数型:流式细胞测量术
Synonyms: Ab;自身抗体 PMN;中性;中性白细胞;中性粒细胞;嗜中性;嗜中性白细胞;多形核;多形核白细胞;多形核粒细胞;多形核粒细胞（PMN） 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 动态 嗜中性粒细胞（中性、中性粒、中性粒细胞、嗜中性、Neu）膜（细胞膜、胞膜） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105286-9