Version 2.78

Part Description

LP231983-0   Neutrophil membrane Ab
Antineutrophil membrane antibodies are antibodies that bind to antigens on the surface of neutrophils. Several specific antigens have been identified, but the IgG Fc receptor type 3b is the primary target. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary AIN there is no association with another pathology. Primary AIN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary AIN usually occurs following a systemic haematologic disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell transplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350 Source: Regenstrief LOINC

Fully-Specified Name

Component
Neutrophil membrane Ab
Property
Imp
Time
Pt
System
Ser/Plas
Scale
Nar
Method

Additional Names

Short Name
Neutrophil membrane Ab SerPl-Imp
Display Name
Neutrophil membrane Ab Nar [Interp]
Consumer Name Alpha Get Info
Interpretation of Neutrophil membrane antibody test result, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
105285-1 Neutrophil Ab screen panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Membrana neutrófila Anticuerpos:Impresión/interpretación del estudio:Punto temporal:Suero o Plasma:Narrativo:
it-IT Italian (Italy) Membrana neutrofili Ab:Imp:Pt:Siero/Plasma:Nar:
Synonyms: anticorpo Impressione/interpretazione di studio Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) neutrofiel membraan As:interpretatie:moment:serum of plasma:tekstueel:
Synonyms: antistof; antilichaam
zh-CN Chinese (China) 嗜中性粒细胞膜 抗体:印象:时间点:血清/血浆:叙述型:
Synonyms: Ab;自身抗体 PMN;中性;中性白细胞;中性粒细胞;嗜中性;嗜中性白细胞;多形核;多形核白细胞;多形核粒细胞;多形核粒细胞（PMN） 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 嗜中性粒细胞（中性、中性粒、中性粒细胞、嗜中性、Neu）膜（细胞膜、胞膜） 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105288-5