10660-9

Cytomegalovirus Ag [Presence] in Tissue by Immune stain

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Part Description

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component: Cytomegalovirus Ag
Property: PrThr
Time: Pt
System: Tiss
Scale: Ord
Method: Immune stain

Additional Names

Long Common Name: Cytomegalovirus Ag [Presence] in Tissue by Immune stain
Short Name: CMV Ag Tiss Ql ImStn
Display Name: CMV Ag Immune stain Ql (Tiss)
Consumer Name Alpha Get Info: Cytomegalovirus (CMV) antigen, Tissue

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0i
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 14909

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Cytomegalie-Virus Ag:Nachweis oder Schwellenwert:Zeitpunkt:Gewebe:Ordinal:Immunfärbung Synonyms: CMV
el-GR	Greek (Greece)	Κυτταρομεγαλοϊός Αντιγόνο:PrThr:Pt:Ιστός:Ord:Ανοσολογική χρώση Synonyms: PrThr
es-AR	Spanish (Argentina)	[antígeno de] citomegalovirus [Ag]:concentración arbitraria:punto en el tiempo:tejido, no especificado:ordinal:tinción inmunológica
es-MX	Spanish (Mexico)	Citomegalovirus Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
es-ES	Spanish (Spain)	Citomegalovirus Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
et-EE	Estonian (Estonia)	Tsütomegaloviirus antigeen:PrThr:Pt:Tis:Ord:Immuunvärv Synonyms: Järgarvuline Juhuslik Kude
fr-CA	French (Canada)	Cytomégalovirus, Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-BE	French (Belgium)	Cytomégalovirus Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique Synonyms: Antigène CMV Coloration. Méthode mmunologique
fr-FR	French (France)	Cytomégalovirus Ag:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-IT	Italian (Italy)	Citomegalovirus, Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
ko-KR	Korean (Korea, Republic Of)	거대세포바이러스 항원:임의농도:검사시점:조직:순위척도:면역염색
nl-NL	Dutch (Netherlands)	Cytomegalovirus Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring Synonyms: antigeen
pl-PL	Polish (Poland)	Wirus cytomegalii Ag:granica wykrywalności:punkt w czasie:tkanka i rozmazy:półilościowy:barwnik immunologiczny Synonyms: Antygen wirusa cytomegalii barwnik immunologiczny Cytomegalowirus
pt-BR	Portuguese (Brazil)	Citomegalovírus Ag:ACnc:Pt:Tecido:Ord:Imunocoloração Synonyms: ; CMV; Cytomgal; Cytomegalo virus; Arbitrary concentration; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; ImStn; Immunostain; Immunohistochemical stain; IHC; Antigen; Antigens; Imun; Imune; Imm; Microbiology
ru-RU	Russian (Russian Federation)	Цитомегаловирус Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TR	Turkish (Turkey)	Cytomegalovirus Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama Synonyms: Mevcut
zh-CN	Chinese (China)	巨细胞病毒抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法 Synonyms: Ag CMV Ag CMV 抗原 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）巨细胞病毒 Ag 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片染法染色方法染色法着色着色方法着色法

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Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.