13604-4
17-Hydroxypregnenolone [Mass/volume] in Serum or Plasma --1 hour post 250 ug corticotropin
Active
Part Descriptions
LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, 17-hydroxypregnenolone (Wikipedia)
LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 [Lab Tests Online:6-17hydroxy/tab/sample]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 17-Hydroxypregnenolone^1H post 250 ug corticotropin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- 17-Hydroxypregnenolone [Mass/volume] in Serum or Plasma --1 hour post 250 ug corticotropin
- Short Name
- 17OH-Preg 1h p 250 ug ACTH SerPl-mCnc
- Display Name
- 17-Hydroxypregnenolone 1 Hr post 250 ug corticotropin [Mass/Vol]
- Consumer Name Alpha Get Info
- 17-Hydroxypregnenolone 1 hr after 250 ug Corticotropin, Blood
Basic Attributes
- Class
- CHAL.ROUTINE
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- Changed Class from "CHAL" to "CHAL.ROUTINE"
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 15448
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG50342-1 | 17-Hydroxypregnenolone^1H post 250 ug corticotropin| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | 17-υδροξυπρογνενολόνη^1 ώρα κατόπιν 250 ug κορτικοτροπίνης: Synonyms: MCnc |
| es-AR | Spanish (Argentina) | 17-hidroxipregnenolona^1 hora después de la administración de 250 ug de corticotrofina: |
| es-ES | Spanish (Spain) | 17-Hidroxipregnenolona^1 hora pos 250 ug corticotropina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | 17-hidroxipregnenolona^1H después de 250 ug de corticotropina: |
| fr-CA | French (Canada) | 17-hydroxyprégnénolone^1 h post 250 ug hormone adrénocorticotrope: |
| fr-FR | French (France) | 17-hydroxyprégnénolone T01h après synacthène (250µg): |
| fr-BE | French (Belgium) | 17-hydroxyprégnénolone^1 h post 250 ug hormone adrénocorticotrope: Synonyms: 1h après ACTH 250µg ACTH |
| it-IT | Italian (Italy) | 17-Idrossipregnenolone^1h post 250 ug corticotropina: Synonyms: 1 ora dopo 250 ug di corticotropina Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma Test di provocazione |
| ko-KR | Korean (Korea, Republic Of) | 17-하이드록시프레그네놀론^부신겉질자극호르몬 250ug 후 1시간: |
| nl-NL | Dutch (Netherlands) | 17-hydroxypregnenolon^60 min na 250 ug ACTH: Synonyms: 1 uur na 250 ug ACTH adrenocorticotroop hormoon; |
| pt-BR | Portuguese (Brazil) | 17-hidroxipregnenolona^60 min após 250 ug corticotrofina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | 17-Гидроксипрегненолон^1 час после 250 мкг кортикотропина: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | 17-Hidroksipregnenolon^1Sa snr 250 ug kortikotropin: |
| zh-CN | Chinese (China) | 17-羟基孕烯醇酮^在给予250 ug促肾上腺皮质激素之后1小时: Synonyms: 17-Alpha-羟基娠烯醇酮; |
Example Units
| Unit | Source |
|---|---|
| ng/dL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=13604-4
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://