Version 2.80

Status Information

Status
DISCOURAGED
Comment
Most laboratories report this in moles. Double check with your lab for reporting units.
Map-To Long Common Name Mapping Guidance
29506-3 2-Oxoadipate/Creatinine [Molar ratio] in Urine

Part Descriptions

LP18408-2   2-Oxoadipate
α-Ketoadipic acid (or 2-oxoadipate) is an intermediate in the metabolism of lysine. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

LP18408-2   2-Oxoadipate
2-Oxoadipic acid is produced from lysine in the cytosol of cells via the saccharopine and the pipecolic acid pathways. Catabolites of hydroxylysine and tryptophan enter these pathways as 2-aminoadipic- -semialdehyde and 2-oxoadipate, respectively. In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. 2-Oxoadipic aciduria is an in-born error of metabolism of lysine, tryptophan, and hydroxylysine, in which abnormal quantities of 2-aminoadipic acid are found in body fluids along with 2-oxoadipic acid. Patients with 2-Oxoadipic acidemias are mentally retarded with hypotonia or seizures. 2-Oxoadipic Aciduria can occur in patients with Kearns-Sayre Syndrome, a progressive disorder with onset prior to 20 years of age in which multiple organ systems are affected, including progressive external ophthalmoplegia, retinopathy, and the age of onset, and these are associated classically with abnormalities in cardiac conduction, cerebellar signs, and elevated cerebrospinal fluid protein. PMID: 10655159, PMID: 16183823, PMID: 11083877 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database , Creatinine

Fully-Specified Name

Component
2-Oxoadipate/Creatinine
Property
MRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Long Common Name
2-Oxoadipate/Creatinine [Mass Ratio] in Urine
Short Name
2-Oxoadipate/Creat Ur
Display Name
2-Oxoadipate/Creatinine (U) [Mass ratio]
Consumer Name Alpha Get Info
2-Oxoadipate/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.42 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) 2-οξο-αδιπικό/Κρεατινίνη:MRto:Pt:Ούρα:Qn:
Synonyms: MRto
es-AR Spanish (Argentina) 2-oxoadipato/creatinina:relación de concentración de masa:punto en el tiempo:orina:cuantitativo:
es-ES Spanish (Spain) 2-Oxoadipato/Creatinina:Relacion de Masa:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) 2-oxoadipato / creatinina:Relación de masa:Punto temporal:Orina:Cuantitativo:
et-EE Estonian (Estonia) 2-oksoadipaat/kreatiniin:MRto:Pt:U:Qn:
Synonyms: Juhuslik Kvantitatiivne Uriin
fr-CA French (Canada) 2-oxoadipate/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif:
fr-BE French (Belgium) 2-oxoadipate/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif:
Synonyms: Rapport de masse
it-IT Italian (Italy) 2-Ossoadipato/Creatinina:MRto:Pt:Urine:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di Massa
ko-KR Korean (Korea, Republic Of) 2-옥소아디페이트/크레아티닌:질량농도비:검사시점:뇨:정량:
nl-NL Dutch (Netherlands) 2-oxoadipaat/creatinine:massaverhouding:moment:urine:kwantitatief:
Synonyms: kreatinine
pt-BR Portuguese (Brazil) 2-Oxoadipato/Creatinina:MCrto:Pt:Urina:Qn:
Synonyms: ; 2Oxo-adipate; 2-oxoadipic acid; Creat; CR; 2Oxo-adipate; mRto; Mass concentration ratio; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; II; Chemistry; UCr
ru-RU Russian (Russian Federation) 2-Оксоадипат/Креатинин:МассОтн:ТчкВрм:Моча:Колич:
Synonyms: Количественный Масс отношение Точка во времени;Момент
tr-TR Turkish (Turkey) 2-Okzoadipat/Kreatinin:KütlOr:Zmlı:İdrar:Kant:
zh-CN Chinese (China) 2-氧代己二酸/肌酐:质量比率:时间点:尿液:定量型:
Synonyms: 2Oxo-己二酸 Ⅱ CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 II UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 时刻;随机;随意;瞬间 来自于同一体系的两种分析物的质量之比;质量比 肌酸内酰胺

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=13677-0