LOINC
Version 2.67

13950-1Hepatitis A virus IgM Ab [Presence] in Serum or Plasma by ImmunoassayActive

Part Descriptions

LP16708-7   Hepatitis A virus
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.

Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis A virus (Wikipedia)

LP38318-9   Hepatitis A virus Ab.IgM
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.

Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis A virus (Wikipedia)

LP16708-7   Hepatitis A virus
Hepatitis A virus (HAV) is a small, non-enveloped single-stranded RNA virus that belongs to the Picornaviridae family, genus Hepatovirus. HAV has six genotypes (I to VI) in which genotypes I to III are human isolates and IV to VI are only simian isolates. Genotypes I to III are subdivided into groups A and B. Genotype I is the most frequently reported. [PMID: 15914081] The clinical manifestations of HAV infection can vary significantly and range from asymptomatic infection, usually seen in young children, to fulminant hepatitis, which can result in death. HAV has a global distribution, and transmission primarily occurs by the fecal-oral route. The risk of HAV transmission through blood products is very low, but there have been some reports of transmission through plasma products, mainly coagulation factors. [PMID: 12186933] [PMID: 1318940] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Hepatitis A virus (Wikipedia)

Fully-Specified Name

Component
Hepatitis A virus Ab.IgM
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
IA

Additional Names

Short Name
HAV IgM SerPl Ql IA
Display Name
HAV IgM IA Ql

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common US Lab Results Rank
319
Common SI Lab Results Rank
319
Common Orders Rank
150

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
24363-4 Acute hepatitis 2000 panel - Serum

Member of these Groups

LG32762-3 Hepatitis A virus

Language Variants Get Info

zh-CNChinese (CHINA)
甲型肝炎病毒 抗体.IgM:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法
nl-NLDutch (NETHERLANDS)
Hepatitis A-virus As.IgM:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay
et-EEEstonian (ESTONIA)
A-hepatiidi viirus antikehad.IgM:PrThr:Pt:S/P:Ord:IA
fr-BEFrench (BELGIUM)
Virus de l'hépatite A Anticorps. IgM:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:IA
fr-CAFrench (CANADA)
Virus de l'hépatite A , IgM:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:IA
fr-FRFrench (FRANCE)
Hépatite A virus Ac IgM:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
fr-CHFrench (SWITZERLAND)
S--hépatite A, IgM; ; EIA
de-DEGerman (GERMANY)
Hepatitis-A-Virus Ak.IgM:AKnz:Pkt:Ser:Ord:EIA
de-CHGerman (SWITZERLAND)
S--Hepatit A, IgM; ; EIA
el-GRGreek (GREECE)
Ιός Ηπατίτιδας Α IgM ανοσοσφαιρίνη:PrThr:Χρονική στιγμή:Ορός/Πλάσμα:Τακτική:IA
it-ITItalian (ITALY)
Epatite A, virus , Ab.IgM:PrThr:Pt:Siero/Plasma:Ord:IA
it-CHItalian (SWITZERLAND)
S--epatite A, IgM; ; EIA
ko-KRKorean (KOREA, REPUBLIC OF)
A형 간염 바이러스 항체.면역글로불린 M:임의농도:검사시점:혈청:순위척도:효소면역측정법
pt-BRPortuguese (BRAZIL)
Hepatite A vírus Ac.IgM:ACnc:Pt:Soro:Ord:Imunoensaio
ru-RURussian (RUSSIAN FEDERATION)
Гепатита А вирус Ат.IgM:PrThr:ТчкВрм:Сыв/Плаз:Пор:IA
es-ARSpanish (ARGENTINA)
[anticuerpo anti - ] virus de hepatitis A [Ac].IgM [Inmunoglobulina M]:concentración arbitraria:punto en el tiempo:suero:ordinal:enzimoinmunoanálisis
es-ESSpanish (SPAIN)
Virus de la Hepatitis A IgM:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-CHSpanish (SWITZERLAND)
S--hepatitis A, IgM; ; EIA
tr-TRTurkish (TURKEY)
Hepatit A virüsü Ab.IgM:MevcEşik:Zmlı:Ser/Plaz:Srl:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=13950-1