14803-1
Lactate dehydrogenase [Enzymatic activity/volume] in Body fluid by Lactate to pyruvate reaction
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Part Descriptions
LP15033-1 Lactate dehydrogenase
Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called hydroxybutyrate dehydrogenase (HBD).
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Source: Wikipedia, D-lactate (Wikipedia)
LP15033-1 Lactate dehydrogenase
Lactate dehydrogenase (LDH, or also called LD) is an oxidoreductase (LD: EC 1.1.1.27) and is the most important clinically of several dehydrogenases occurring in human serum. LDH catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD. When disease, injury, or toxic material damages tissues, cells release LDH into the bloodstream. Since LDH is a fairly stable enzyme, it has been widely used to evaluate the presence of damage and toxicity of tissue and cells. LDH is cytoplasmic in its cellular location and in any one tissue is composed of one or two of five possible isoenzymes. While many of its clinical applications involve quantification of one or more specific serum isoenzymes, an estimate of total LDH is usually required. Lactate dehydrogenase catalyzes the reversible reaction: L-lactate + NAD <--> pyruvate + NADH. Testing methods either measure the increase in NADH produced in the lactate-to-pyruvate reaction or the decrease in NADH produced in the pyruvate-to-lactate reaction. PMID: 3882046. Reference ranges are highly method dependent. The pyruvate-to-lactate reaction is preferred theoretically because the equilibrium constant is large and the rate for any amount of enzyme is 2-3 times faster, thus smaller sample and shorter observation periods are needed. Disadvantages of the pyruvate-to-lactate reaction are loss of linearity as compared with the lactate-to-pyruvate reaction, and greater substrate inhibition of the enzyme. [Tietz Fourth Edition]
Source: Regenstrief LOINC
LP7238-1 Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic.
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. | Lactate Dehydrogenase (LD) |
Fully-Specified Name
- Component
- Lactate dehydrogenase
- Property
- CCnc
- Time
- Pt
- System
- Body fld
- Scale
- Qn
- Method
- Reaction: lactate to pyruvate
Additional Names
- Short Name
- LDH Fld L to P-cCnc
- Display Name
- LDH Lactate to pyruvate reaction (Body fld) [Catalytic activity/Vol]
- Consumer Name Alpha Get Info
- Lactate Dehydrogenase (LDH), Body fluid
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 2420
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Lactatdehydrogenase: Synonyms: LDH |
| de-AT | German (Austria) | Synonyms: LDH /Körperflüssigkeit |
| es-AR | Spanish (Argentina) | lactato deshidrogenasa: |
| es-ES | Spanish (Spain) | Lactato deshidrogenasa: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Lactato deshidrogenasa: |
| fr-CA | French (Canada) | Lactate déshydrogénase: |
| fr-FR | French (France) | Lactate déhydrogénase: |
| fr-BE | French (Belgium) | Lactate déshydrogénase: Synonyms: LDH |
| it-IT | Italian (Italy) | Lattato deidrogenasi: Synonyms: Chimica Concentrazione Catalitica Liquido corporeo Punto nel tempo (episodio) Reazione- lattato in piruvato |
| ko-KR | Korean (Korea, Republic Of) | 젖산 탈수소효소: |
| nl-NL | Dutch (Netherlands) | lactaatdehydrogenase: |
| pl-PL | Polish (Poland) | Dehydrogenaza mleczanowa: |
| pt-BR | Portuguese (Brazil) | Desidrogenase Láctica: Synonyms: ; |
| tr-TR | Turkish (Turkey) | Laktat dehidrojenaz: |
| uk-UA | Ukrainian (Ukraine) | Лактатдегідрогеназа: Synonyms: 2-Hydroxypropanoic acid; |
| zh-CN | Chinese (China) | 乳酸脱氢酶: Synonyms: 2-羟基-丙酸; |
Example Units
| Unit | Source |
|---|---|
| U/L | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=14803-1
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright