Log In

Part Descriptions

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called hydroxybutyrate dehydrogenase (HBD). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, D-lactate (Wikipedia)

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH, or also called LD) is an oxidoreductase (LD: EC 1.1.1.27) and is the most important clinically of several dehydrogenases occurring in human serum. LDH catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD. When disease, injury, or toxic material damages tissues, cells release LDH into the bloodstream. Since LDH is a fairly stable enzyme, it has been widely used to evaluate the presence of damage and toxicity of tissue and cells. LDH is cytoplasmic in its cellular location and in any one tissue is composed of one or two of five possible isoenzymes. While many of its clinical applications involve quantification of one or more specific serum isoenzymes, an estimate of total LDH is usually required. Lactate dehydrogenase catalyzes the reversible reaction: L-lactate + NAD <--> pyruvate + NADH. Testing methods either measure the increase in NADH produced in the lactate-to-pyruvate reaction or the decrease in NADH produced in the pyruvate-to-lactate reaction. PMID: 3882046. Reference ranges are highly method dependent. The pyruvate-to-lactate reaction is preferred theoretically because the equilibrium constant is large and the rate for any amount of enzyme is 2-3 times faster, thus smaller sample and shorter observation periods are needed. Disadvantages of the pyruvate-to-lactate reaction are loss of linearity as compared with the lactate-to-pyruvate reaction, and greater substrate inhibition of the enzyme. [Tietz Fourth Edition] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Lactate dehydrogenase:CCnc:Pt:Ser/Plas:Qn:Reaction: lactate to pyruvate
Long Common Name
Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
Short Name
LDH SerPl L to P-cCnc
Display Name
LDH Lactate to pyruvate reaction [Catalytic activity/Vol]
Consumer Name Alpha Get Info
Lactate Dehydrogenase (LDH), Blood

Part Model Get Info

  • Component
    Lactate dehydrogenase
    LP15033-1
    • Analyte
      Lactate dehydrogenase
      LP15033-1
      • Component Numerator
        Lactate dehydrogenase
        LP15033-1
        • Component Numerator Core
          Lactate dehydrogenase
          LP15033-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CCnc
    LP6789-4
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Reaction: lactate to pyruvate
    LP6479-2

Associated Observations

95405-7 Assay related variables panel [PhenX]

This panel contains a collection of ask-at-order entry questions and associated observations that may be included within various PhenX protocols for biomarker testing. Each protocol varies as to the items asked & recorded, so not all terms will be used but are displayed together for users to find the appropriate LOINCs.

LOINCNameR/O/CCardinalityExample UCUM Units
95405-7Assay related variables panel
Indent30525-0Agea
Indent46098-0Sex
Indent66165-2Last ate or drank anything other than plain water [Date and time]
Indent80331-2Date and time of last void{clock_time}
Indent66177-7Do you have hemophilia?
Indent94741-6Cancer chemotherapy received in the past 4W
Indent66178-5Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Indent66504-2Exclusion Criteria
Indent41395-5Collection date of Urine
Indent74751-9Collection time of Urine{clock_time}
Indent94331-6Specimen Collection procedure comment
Indent95044-4Patient refused specimen collection
Indent94846-3History of Specimen collection problem
Indent94847-1Reason specimen not collected
Indent77301-0Reason care action performed or not
Indent66180-1Was blood drawn?
Indent66181-9Was full sample obtained?
Indent94330-8Specimen Processing comment
Indent8251-1Service comment
Indent85069-3Lab test method [Type]
Indent66200-7Repeatability of the assay{ratio}
Indent66201-5Coefficient of variation for the assay{CV}
Indent66208-0Make of the equipment used to perform...
Indent74719-6Manufacturer of the equipment used
Indent74720-4Device name

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
526

Member of these Panels

LOINCLong Common Name
42929-0Lactate dehydrogenase panel - Serum or Plasma

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Laktátdehydrogenáza:Katalytická koncentrace:Časový bod:Sérum/plazma:Kvantitativní:Reakce laktát na pyruvát
de-DEGerman (Germany)Lactatdehydrogenase:Katalytische Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:Reaktion: Lactat zu Pyruvat
Synonyms: LDH
de-ATGerman (Austria)Synonyms: LDH
el-GRGreek (Greece)Γαλακτική αφυδρογονάση:CCnc:Pt:Ορός/Πλάσμα:Qn:Αντίδραση: γαλακτικό προς πυροσταφυλικό
Synonyms: CCnc CHEM Pt Qn Αντίδραση: γαλακτικό προς πυροσταφυλικό Γαλακτική αφυδρογονάση Γαλακτικό οξύ Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)lactato deshidrogenasa:concentración catalítica:punto en el tiempo:suero/plasma:cuantitativo:reacción: lactato a piruvato
es-ESSpanish (Spain)Lactato deshidrogenasa:Concentración Catalítica:Punto temporal:Suero o Plasma:Qn:Reacción - lactato piruvato
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Lactato deshidrogenasa:Concentración catalítica:Punto temporal:Suero o Plasma:Cuantitativo:Reacción - lactato a piruvato
fr-CAFrench (Canada)Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:Sérum/Plasma:Quantitatif:Réaction: lactate en pyruvate
fr-FRFrench (France)Lactate déshydrogénase:Catalytique/Volume:Ponctuel:Sérum/Plasma:Numérique:Réaction : Lactate vers Pyruvate
fr-BEFrench (Belgium)Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:Sérum/Plasma:Quantitatif:Réaction: lactate en pyruvate
Synonyms: LDH
it-ITItalian (Italy)Lattato deidrogenasi:CCnC:Pt:Siero/Plasma:Qn:Reazione: lattato in piruvato
Synonyms: Chimica Concentrazione Catalitica Plasma Punto nel tempo (episodio) Reazione- lattato in piruvato Siero Siero o Plasma
ko-KRKorean (Korea, Republic Of)젖산 탈수소효소:촉매농도:검사시점:혈청/혈장:정량 :반응:젖산에서에서 피루브산염 반응:
nl-NLDutch (Netherlands)lactaatdehydrogenase:enzymatische activiteit/volume:moment:serum of plasma:kwantitatief:reactie: lactaat naar pyruvaat
pl-PLPolish (Poland)Dehydrogenaza mleczanowa:stężenie katalityczne:punkt w czasie:surowica lub osocze:ilościowy:reakcja L-P, mleczan-pirogronian
pt-BRPortuguese (Brazil)Desidrogenase Láctica:CCnc:Pt:Sor/Plas:Qn:Reação de lactato a piruvato
Synonyms: ; LDH; L.D.H; Lactic acid dehydrogenase; LD; L-lactate dehydrogenase; Lact; 2-hydroxy-propionic acid; 2-hydroxy-propionate; Catalytic Concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; L to P; Rxn; React; Dehydrog; Dehyrdogenase; Chemistry
tr-TRTurkish (Turkey)Laktat dehidrojenaz:KtlKons:Zmlı:Ser/Plaz:Kant:Reaksiyon: laktat tan piruvat a
uk-UAUkrainian (Ukraine)Лактатдегідрогеназа:Каталітична Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:Реакція - лактат до піруват
Synonyms: 2-Hydroxypropanoic acid; 2-hydroxy-propionate; 2-hydroxy-propionic acid; Catalytic Concentration; Chemistry; Dehydrog; Dehyrdogenase; L to P; L.D.H; Lact; Lactic acid; Lactic acid dehydrogenase; LD; LDH; L-lactate; L-lactate dehydrogenase; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; React; Rxn; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Tumor marker; UniversalLabOrders
zh-CNChinese (China)乳酸脱氢酶:催化浓度:时间点:血清/血浆:定量型:反应: 乳酸至丙酮酸
Synonyms: 2-羟基-丙酸;Lact;L-乳酸 L.D.H;LD;LDH;L-乳酸脱氢酶 React Rxn 乳酸 - 丙酮酸转化法;乳酸 -> 丙酮酸转化法;乳酸转化为丙酮酸的反应;反应: 乳酸 - 丙酮酸;反应: 乳酸 -> 丙酮酸 催化浓度(单位体积);单位体积内酶的单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 去氢酶 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清或血浆

Example Units

UnitSource
U/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=14804-9