15189-4
Kappa light chains/Lambda light chains [Mass Ratio] in Serum
Active
Part Description
LP15030-7 Immunoglobulin light chains.kappa
All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. PMID: 6802926 ] [Lab Tests Online:free-light/tab/test]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda
- Property
- MRto
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- Kappa LC/Lambda Ser
- Display Name
- Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda (S) [Mass ratio]
- Consumer Name Alpha Get Info
- Immunoglobulin light chains.kappa/Immunoglobulin Light Chains.lambda, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Change Reason
- The LCN was changed from 'Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda' to 'Kappa light chains/Lambda light chains' for readability.
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 688
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG3250-0 | Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Immunglobulin Leichtketten.kappa/Immunglobulin Leichtketten.lambda: |
de-AT | German (Austria) | Synonyms: Kappa/Lambda-Ratio |
es-MX | Spanish (Mexico) | Cadenas ligeras de inmunoglobulina kappa / Cadenas ligeras de inmunoglobulina lambda: |
es-AR | Spanish (Argentina) | cadenas livianas de inmunoglobulina.kappa/cadenas livianas de inmunoglobulina.lambda: |
es-ES | Spanish (Spain) | Cadenas ligeras de las inmunoglobulinas.kappa/Cadenas ligeras de inmunoglobulina (cadenas lambda): Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | Immuunoglobuliini kerged ahelad.kapa/immuunoglobuliini kerged ahelad.lambda: Synonyms: Immuunglobuliinide kerged kapaahelad Immuunglobuliinide kerged lambdaahelad Juhuslik Kvantitatiivne Seerum |
fr-CA | French (Canada) | Chaînes légères d'immunoglobulines.kappa/Chaînes légères d'immunoglobulines.lambda: |
fr-BE | French (Belgium) | Chaînes légères immunoglobulines.kappa/Chaînes légères d'immunoglobulines.lambda: Synonyms: LC LC. Kappa LC. Lambda LC.Lambda Rapport de masse |
fr-FR | French (France) | Immunoglobuline chaines légères kappa/lambda: |
it-IT | Italian (Italy) | Immunoglobuline, catene leggere.kappa/Immunoglobuline, catene leggere.lambda: Synonyms: Catene leggere delle immunoglobuline Catene leggere kappa delle immunoglobuline Catene leggere lambda delle immunoglobuline Chimica Punto nel tempo (episodio) Rapporto di Massa Siero |
ko-KR | Korean (Korea, Republic Of) | 카파면역글로불린 경쇄/람다면역글로불린 경쇄: |
nl-NL | Dutch (Netherlands) | immunoglobuline lichte ketens.kappa/lichte-keten immunoglobuline.lambda: Synonyms: immunoglobuline lichte ketens.lambda |
pl-PL | Polish (Poland) | Łańcuchy lekkie immunoglobuliny.kappa/łańcuchy lekkie lambda immunoglobuliny: Synonyms: Łańcuchy immunoglobulin lekkie kappa / łańcuchy immunoglobulin lekkie lambda Łańcuchy lekkie immunoglobulin Łańcuchy lekkie kappa immunoglobuliny Łańcuchy lekkie lambda immunoglobuliny |
pt-BR | Portuguese (Brazil) | Imunoglobulinas cadeias leves.kappa/Imunoglobulinas cadeias leves.lambda: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Иммуноглобулин легкие цепи.каппа/Иммуноглобулин легкие цепи.лямбда: Synonyms: Количественный Масс отношение Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | İmmünglobulin hafif zincirler.kappa/İmmünglobulin hafif zincirler.lambda: |
zh-CN | Chinese (China) | 免疫球蛋白轻链.Kappa 型/免疫球蛋白轻链.Lambda: Synonyms: Bence Jones 氏蛋白; |
Example Units
Unit | Source |
---|---|
{ratio} | Example UCUM Units |
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