LOINC
Version 2.73

15189-4Kappa light chains/Lambda light chains [Mass Ratio] in SerumActive

Part Description

LP15030-7   Immunoglobulin light chains.kappa
All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. [PMID:6802926] [Lab Tests Online:free-light/tab/test] Source: Regenstrief LOINC

Fully-Specified Name

Component
Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda
Property
MRto
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
Kappa LC/Lambda Ser
Display Name
Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda (S) [Mass ratio]
Consumer Name Alpha
Immunoglobulin light chains.kappa/Immunoglobulin Light Chains.lambda, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.73
Change Reason
The LCN was changed from 'Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda' to 'Kappa light chains/Lambda light chains' for readability.
Order vs. Observation
Observation
Common US Lab Results Rank
688

Member of these Groups

LG3250-0 Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda|MRto|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
免疫球蛋白轻链.Kappa 型/免疫球蛋白轻链.Lambda:质量比率:时间点:血清:定量型:
nl-NLDutch (Netherlands)
immunoglobuline lichte ketens.kappa/lichte-keten immunoglobuline.lambda:massaverhouding:moment:serum:kwantitatief:
et-EEEstonian (Estonia)
Immuunoglobuliini kerged ahelad.kapa/immuunoglobuliini kerged ahelad.lambda:MRto:Pt:S:Qn:
fr-BEFrench (Belgium)
Chaînes légères immunoglobulines.kappa/Chaînes légères d'immunoglobulines.lambda:Ratio de masse:Temps ponctuel:Sérum:Quantitatif:
fr-CAFrench (Canada)
Chaînes légères d'immunoglobulines.kappa/Chaînes légères d'immunoglobulines.lambda:Ratio de masse:Temps ponctuel:Sérum:Quantitatif:
fr-FRFrench (France)
Immunoglobuline chaines légères kappa/lambda:Masse ratio:Ponctuel:Sérum:Numérique:
de-DEGerman (Germany)
Immunglobulin Leichtketten.kappa/Immunglobulin Leichtketten.lambda:Massenverhältnis:Zeitpunkt:Serum:Quantitativ:
it-ITItalian (Italy)
Immunoglobuline, catene leggere.kappa/Immunoglobuline, catene leggere.lambda:MRto:Pt:Siero:Qn:
ko-KRKorean (Korea, Republic of)
카파면역글로불린 경쇄/람다면역글로불린 경쇄:질량농도비:검사시점:혈청:정량:
pt-BRPortuguese (Brazil)
Imunoglobulinas cadeias leves.kappa/Imunoglobulinas cadeias leves.lambda:MCrto:Pt:Soro:Qn:
ru-RURussian (Russian Federation)
Иммуноглобулин легкие цепи.каппа/Иммуноглобулин легкие цепи.лямбда:МассОтн:ТчкВрм:Сыв:Колич:
es-ARSpanish (Argentina)
cadenas livianas de inmunoglobulina.kappa/cadenas livianas de inmunoglobulina.lambda:relación de concentración de masa:punto en el tiempo:suero:cuantitativo:
es-MXSpanish (Mexico)
Cadenas ligeras de inmunoglobulina kappa / Cadenas ligeras de inmunoglobulina lambda:Relación de masa:Punto temporal:Suero:Cuantitativo:
es-ESSpanish (Spain)
Cadenas ligeras de las inmunoglobulinas.kappa/Cadenas ligeras de inmunoglobulina (cadenas lambda):Relacion de Masa:Punto temporal:Suero:Qn:
tr-TRTurkish (Turkey)
İmmünglobulin hafif zincirler.kappa/İmmünglobulin hafif zincirler.lambda:KütlOr:Zmlı:Ser:Kant:

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=15189-4