Version 2.77

Part Descriptions

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called hydroxybutyrate dehydrogenase (HBD). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, D-lactate (Wikipedia)

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH, or also called LD) is an oxidoreductase (LD: EC 1.1.1.27) and is the most important clinically of several dehydrogenases occurring in human serum. LDH catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD. When disease, injury, or toxic material damages tissues, cells release LDH into the bloodstream. Since LDH is a fairly stable enzyme, it has been widely used to evaluate the presence of damage and toxicity of tissue and cells. LDH is cytoplasmic in its cellular location and in any one tissue is composed of one or two of five possible isoenzymes. While many of its clinical applications involve quantification of one or more specific serum isoenzymes, an estimate of total LDH is usually required. Lactate dehydrogenase catalyzes the reversible reaction: L-lactate + NAD <--> pyruvate + NADH. Testing methods either measure the increase in NADH produced in the lactate-to-pyruvate reaction or the decrease in NADH produced in the pyruvate-to-lactate reaction. PMID: 3882046. Reference ranges are highly method dependent. The pyruvate-to-lactate reaction is preferred theoretically because the equilibrium constant is large and the rate for any amount of enzyme is 2-3 times faster, thus smaller sample and shorter observation periods are needed. Disadvantages of the pyruvate-to-lactate reaction are loss of linearity as compared with the lactate-to-pyruvate reaction, and greater substrate inhibition of the enzyme. [Tietz Fourth Edition] Source: Regenstrief LOINC

Fully-Specified Name

Component
Lactate dehydrogenase
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method

Additional Names

Short Name
LDH Ur Ql
Display Name
LDH Ql (U)
Consumer Name Alpha Get Info
Lactate Dehydrogenase (LDH), Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0l
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
19196

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Γαλακτική αφυδρογονάση:PrThr:Χρονική στιγμή:Ούρα:Τακτική:
Synonyms: LDH
es-AR Spanish (Argentina) lactato deshidrogenasa:concentración arbitraria:punto en el tiempo:orina:ordinal:
es-ES Spanish (Spain) Lactato deshidrogenasa:PrThr:Punto temporal:Orina:Ord:
es-MX Spanish (Mexico) Lactato deshidrogenasa:Presencia o umbral:Punto temporal:Orina:Ordinal:
et-EE Estonian (Estonia) Laktaadi dehüdrogenaas:PrThr:Pt:U:Ord:
Synonyms: Järgarvuline Juhuslik Uriin
fr-CA French (Canada) Lactate déshydrogénase:Présence-Seuil:Temps ponctuel:Urine:Ordinal:
fr-FR French (France) Lactate déhydrogénase:Présence/Seuil:Ponctuel:Urine:Qualitatif:
fr-BE French (Belgium) Lactate déshydrogénase:PrThr:Temps ponctuel:Urine:Ordinal:
Synonyms: LDH
it-IT Italian (Italy) Lattato deidrogenasi:PrThr:Pt:Urine:Ord:
Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio)
ko-KR Korean (Korea, Republic Of) 젖산 탈수소효소:임의농도:검사시점:뇨:순위척도:
nl-NL Dutch (Netherlands) lactaatdehydrogenase:aanwezigheid:moment:urine:ordinaal:
pl-PL Polish (Poland) Dehydrogenaza mleczanowa:granica wykrywalności:punkt w czasie:mocz:półilościowy:
pt-BR Portuguese (Brazil) Desidrogenase Láctica:ACnc:Pt:Urina:Ord:
Synonyms: ; LDH; L.D.H; Lactic acid dehydrogenase; LD; L-lactate dehydrogenase; Lact; 2-hydroxy-propionic acid; 2-hydroxy-propionate; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Ql; Ordinal; QL; Qualitative; Qual; Screen; Dehydrog; Dehyrdogenase; Chemistry
ru-RU Russian (Russian Federation) Лактатдегидрогеназа:PrThr:ТчкВрм:Моча:Пор:
Synonyms: Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) Laktat dehidrojenaz:MevcEşik:Zmlı:İdrar:Srl:
Synonyms: Mevcut
zh-CN Chinese (China) 乳酸脱氢酶:存在情况或阈值:时间点:尿液:序数型:
Synonyms: 2-羟基-丙酸;Lact;L-乳酸 L.D.H;LD;LDH;L-乳酸脱氢酶 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 去氢酶 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 尿;小便;下泉 时刻;随机;随意;瞬间

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CodeSystem lookup
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