18229-5
Heparan sulfate [Presence] in Serum or Plasma
Active
Part Description
LP15629-6 Heparan sulfate
Heparan sulfate is a derived disaccharide that accumulates in lysosomes, extracellular matrix, and body fluids of people with mucopolysaccharidoses (MPSs). MPSs are rare disorders caused by a deficiency of enzymes that break down glycosaminoglycans (GAGs). Symptoms of MPS vary due to which storage product accumulates and the level of enzymatic function or concentration that remains. Symptoms include musculoskeletal, airway, cardiac, and central nervous system disorders. Treatments include hematopoietic stem cell transplantation for the more critical forms of MPS and intravenous enzyme replacement therapy for the others. Treatment is most effective when it is initiated before irreversible tissue damage has occurred. Because MPS is so rare and the symptoms so variable, it is difficult to diagnose in its earliest stages. A solution to that problem is the development of newborn screening assays that can detect heparan sulfate, though the levels in the dried blood spot samples do not appear to predict the severity of disease. The pattern of dermatan and heparan sulfate can help distinguish between the different MPSs. PMID: 23084433
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Heparan sulfate
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
Additional Names
- Short Name
- Heparan sulfate SerPl Ql
- Display Name
- Heparan sulfate Ql
- Consumer Name Alpha Get Info
- Heparan sulfate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0l
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | heparán sulfato: |
es-ES | Spanish (Spain) | Heparán sulfato: |
es-MX | Spanish (Mexico) | Sulfato de Heparán: |
et-EE | Estonian (Estonia) | Heparaansulfaat: Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Héparane-sulfate: |
fr-FR | French (France) | Héparane sulfate: |
fr-BE | French (Belgium) | Héparane-sulfate: Synonyms: SO4 |
it-IT | Italian (Italy) | Eparan solfato: Synonyms: Chimica Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 헤파란 황산염: |
nl-NL | Dutch (Netherlands) | heparansulfaat: |
pt-BR | Portuguese (Brazil) | Sulfato de heparina: Synonyms: SO4-2; |
ru-RU | Russian (Russian Federation) | Гепаран сульфат: Synonyms: Гепарансульфат Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Heparan sülfat: Synonyms: Mevcut |
zh-CN | Chinese (China) | 硫酸类肝素: Synonyms: SO4; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=18229-5
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright