1904-2

Ascorbate [Presence] in Urine

Active

Part Descriptions

LP15254-3   Ascorbate
Promotes the conversion of tropocollagen to collagen and is involved in the production of adrenal cortical steroids and the metabolism of tyrosine and folate. In addition, it appears to function in a variety of other metabolic processes in which its role has not been characterized.The need for Vitamin C can be increased by the use of asprin, oral contraceptives, tetracyclines and other medications. Chronic injestion of large doses has been a common-place practice for several years with no apparently harmful effect. Source: Regenstrief Institute

LP15254-3   Ascorbate
Ascorbic acid is an essential nutrient in human diets, and is necessary to maintain connective tissue and bone. The biologically active form of ascorbic acid is vitamin C. Vitamin C is a water soluble vitamin. Primates (including humans) and a few other species in all divisions of the animal kingdom, notably the guinea pig, have lost the ability to synthesize ascorbic acid and must obtain it in their food. Ascorbic acid is an electron donor for enzymes involved in collagen hydroxylation, biosynthesis of carnitine and norepinephrine, tyrosine metabolism, and amidation of peptide hormones. Ascrobic acid (vitamin C) deficiency causes scurvy. The amount of vitamin C necessary to prevent scurvy may not be adequate to maintain optimal health. The ability of vitamin C to donate electrons also makes it a potent water-soluble antioxidant that readily scavenges free radicals such as molecular oxygen, superoxide, hydroxyl radical, and hypochlorous acid. In this setting, several mechanisms could account for a link between vitamin C and heart disease. One is the relation between LDL oxidation and vitamins C and E. Vitamin C in vitro can recycle vitamin E, which can donate electrons to prevent LDL oxidation in vitro. As the lipid-phase vitamin E is oxidized, it can be regenerated by aqueous vitamin C. Other possibilities are that vitamin C could decrease cholesterol by mechanisms not well characterized, or could improve vasodilatation and vascular reactivity, perhaps by decreasing the interactions of nitric oxide with oxidants. PMID: 10799361. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Ascorbate

Fully-Specified Name

Component

Ascorbate

Property

PrThr

Time

Pt

System

Urine

Scale

Ord

Method

Additional Names

Short Name

Vit C Ur Ql

Display Name

Ascorbate Ql (U)

Consumer Name Alpha Get Info

Ascorbate, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

1733

Language Variants Get Info

Related Names

• Ascorbic acid
• c702
• Chemistry
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• UA
• UR
• Urn
• Vit C
• Vitamin C

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CodeSystem lookup

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LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.