Version 2.80

Part Descriptions

LP17184-0   17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , 17-hydroxypregnenolone (Wikipedia)

LP17184-0   17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 [Lab Tests Online:6-17hydroxy/tab/sample] Source: Regenstrief LOINC

Fully-Specified Name

Component
17-Hydroxypregnenolone
Property
MRat
Time
24H
System
Urine
Scale
Qn
Method

Additional Names

Long Common Name
17-Hydroxypregnenolone [Mass/time] in 24 hour Urine
Short Name
17OH-Preg 24h Ur-mRate
Display Name
17-Hydroxypregnenolone (24H U) [Mass/Time]
Consumer Name Alpha Get Info
17-Hydroxypregnenolone, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
95556-7 Adrenal cancer risk assessment and urine steroid fractions panel

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) 17-υδροξυπρογνενολόνη:MRat:24H:Ούρα:Qn:
Synonyms: MRat
es-AR Spanish (Argentina) 17-hidroxipregnenolona:índice de masa:24 horas:orina:cuantitativo:
es-ES Spanish (Spain) 17-Hidroxipregnenolona:Indice de masa:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) 17-hidroxipregnenolona:Tasa de masa:24H:Orina:Cuantitativo:
et-EE Estonian (Estonia) 17-hüdroksüpregnenoloon:MRat:24 tunni:U:Qn:
Synonyms: Kvantitatiivne Uriin
fr-CA French (Canada) 17-hydroxyprégnénolone:Débit de masse:24 h:Urine:Quantitatif:
fr-FR French (France) 17-hydroxyprégnénolone:Masse/Temps:24H:Urine:Numérique:
fr-BE French (Belgium) 17-hydroxyprégnénolone:Débit de masse:24 h:Urine:Quantitatif:
it-IT Italian (Italy) 17-Idrossipregnenolone:MRat:24h:Urine:Qn:
Synonyms: 24 Ore Chimica Indice di Massa
ko-KR Korean (Korea, Republic Of) 17-하이드록시프레그네놀론:질량율:24시간:뇨:정량:
nl-NL Dutch (Netherlands) 17-hydroxypregnenolon:massa/tijd:24 uur:urine:kwantitatief:
Synonyms: 24U
pt-BR Portuguese (Brazil) 17-hidroxipregnenolona:MRat:24H:Urina:Qn:
Synonyms: ; 17OH-Preg; 17 hydroxy pregnenolone; 17-alpha-Hydroxypregnenolone; mRate; Mass rate; 1 day; 24 hours; 24HR; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU Russian (Russian Federation) 17-Гидроксипрегненолон:МассСк:24 часа:Моча:Колич:
Synonyms: Количественный Массовая скорость
tr-TR Turkish (Turkey) 17-Hidroksipregnenolon:KütlHz:24Sa:İdrar:Kant:
zh-CN Chinese (China) 17-羟基孕烯醇酮:质量速率:24小时:尿液:定量型:
Synonyms: 17-Alpha-羟基娠烯醇酮;17-Alpha-羟基孕 5 烯 3β醇 20 酮;17-Alpha-羟基孕烯诺龙;17-Alpha-羟基孕烯醇酮;17-Alpha-羟基孕甾烯醇酮;17OH-Preg;17-α-羟基娠烯醇酮;17-α-羟基孕 5 烯 3β醇 20 酮;17-α-羟基孕烯诺龙;17-α-羟基孕烯醇酮;17-α-羟基孕甾烯醇酮;17-羟基娠烯醇酮;17-羟基孕 5 烯 3β醇 20 酮;17-羟基孕烯诺龙;17-羟基孕甾烯醇酮;17-羟娠烯醇酮;17-羟孕 5 烯 3β醇 20 酮 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 单位时间内的质量数;质量速率(单位时间) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉

Example Units

Unit Source
mg/(24.h) Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=21037-7