25083-7

2-Oxo,3-Methylvalerate/Creatinine [Molar ratio] in Urine

Active

Part Descriptions

LP18407-4 2-Oxo,3-Methylvalerate
3-Methyl-2-oxovaleric acid is a metabolite of isoleucine in man, animals and bacteria. It is the alpha-keto acid analogue of isoleucine. 3-Methyl-2-oxovaleric acid is produced from isoleucine by cytosolic branched chain aminotransferase 1 (EC:2.6.1.42), whereupon it is further degraded by branched chain keto acid dehydrogenase E1 to 2-Methyl-1-hydroxybutyl-ThPP. It is used as a clinical marker for maple syrup urine disease (MSUD). MSUD is caused by a deficiency of the branched-chain -keto acid dehydrogenase compex resulting in an accumulation of branched-chain amino acids and the corresponding -keto-and -hydroxy acids in blood, urine and cerebrospinal fluid causing neurological damage and mental retardation. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 2-Oxo,3-Methylvalerate

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component: 2-Oxo,3-Methylvalerate/Creatinine
Property: SRto
Time: Pt
System: Urine
Scale: Qn
Method

Additional Names

Long Common Name: 2-Oxo,3-Methylvalerate/Creatinine [Molar ratio] in Urine
Short Name: 2Oxo3Me-valerate/Creat Ur-sRto
Display Name: 2-Oxo,3-Methylvalerate/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info: 2-Oxo,3-Methylvalerate/Creatinine, Urine

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.00
Last Updated: Version 2.73
Order vs. Observation: Both
Common Test Rank Get Info: 3853

Member of these Panels

LOINC	Long Common Name
48797-5	Organic acids panel - Urine

Member of these Groups Get Info

LOINC Group	Group Name
LG35393-4	2-Oxo,3-Methylvalerate/Creatinine\|SRto\|Urine

Language Variants Get Info

Tag	Language	Translation
es-AR	Spanish (Argentina)	2-oxo,3-metilvalerato/creatinina:relación de concentración de la sustancia:punto en el tiempo:orina:cuantitativo:
es-ES	Spanish (Spain)	2-Oxo,3-Metilvalerato/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	2-oxo, 3-metilvalerato / creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-CA	French (Canada)	2-oxo,3-méthylvalérate/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
fr-FR	French (France)	2-oxo-3-méthylvalérate/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
fr-BE	French (Belgium)	2-oxo,3-méthylvalérate/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
it-IT	Italian (Italy)	2-Osso,3-Metilvalerato/Creatinina:Srto:Pt:Urine:Qn: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza
ko-KR	Korean (Korea, Republic Of)	2-옥소,3-메틸발레레이트/크레아티닌:물질구성비:검사시점:뇨:정량:
nl-NL	Dutch (Netherlands)	2-oxo,3-methylvaleraat/creatinine:molaire verhouding:moment:urine:kwantitatief: Synonyms: kreatinine
pt-BR	Portuguese (Brazil)	2-Oxo,3-Metilvalerato/Creatinina:SCrto:Pt:Urina:Qn: Synonyms: ; 2Oxo3Me-valerate; 2-keto-3-methylvaleric acid; 2-keto-3-methylvalerate; 2-oxo,3-methylvaleric acid; Creat; CR; 2Oxo3Me-valerate; sRto; Substance concentration ratio; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; III; II; Chemistry; UCr
ru-RU	Russian (Russian Federation)	2-Оксо,3-Метилвалерат/Креатинин:МольОтн:ТчкВрм:Моча:Колич: Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR	Turkish (Turkey)	2-Okzo,3-Metilvalerat/Kreatinin:SOrn:Zmlı:İdrar:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	2-氧代,3-甲基戊酸/肌酐:物质的量比率:时间点:尿液:定量型: Synonyms: 2Oxo3Me-戊酸;2-酮-3-甲基戊酸;2-酮基-3-甲基戊酸 Ⅱ Ⅲ CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 II III UCr 三化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类叁可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐时刻;随机;随意;瞬间物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值肌酸内酰胺

Example Units

Unit	Source
mmol/mol cr	REGENSTRIEF
mmol/mol{creat}	Example UCUM Units

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