Version 2.77

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus DNA
Property
PrThr
Time
Pt
System
Bld
Scale
Ord
Method
Probe.amp.sig

Additional Names

Short Name
CMV DNA Bld Ql Probe+sig amp
Display Name
CMV DNA Probe+sig amp Ql (Bld)
Consumer Name Alpha Get Info
Cytomegalovirus (CMV), Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.00
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
Order vs. Observation
Both
Common Test Rank Get Info
7082

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus DNA:Nachweis oder Schwellenwert:Zeitpunkt:Blut:Ordinal:Sondendetektion mit Signalamplifikation
Synonyms: CMV
es-AR Spanish (Argentina) ADN de citomegalovirus:concentración arbitraria:punto en el tiempo:sangre:ordinal:sonda con amplificación de la señal
es-ES Spanish (Spain) Citomegalovirus ADN:PrThr:Punto temporal:Sangre:Ord:Sonda con amplificación de señal
es-MX Spanish (Mexico) ADN de citomegalovirus:Presencia o umbral:Punto temporal:Sangre:Ordinal:Sonda con amplificación de señal
fr-CA French (Canada) Cytomégalovirus , ADN:Présence-Seuil:Temps ponctuel:Sang:Ordinal:Sonde avec amplification du signal
fr-FR French (France) Cytomégalovirus ADN:Présence/Seuil:Ponctuel:Sang:Qualitatif:PCR amplification du signal
fr-BE French (Belgium) Cytomégalovirus ADN:PrThr:Temps ponctuel:Sang:Ordinal:Sonde avec amplification du signal
Synonyms: CMV
it-IT Italian (Italy) Citomegalovirus DNA:PrThr:Pt:Sangue:Ord:Sonda.amp.sig
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sangue Sonda con amplificazione Sonda con amplificazione del segnale Sonda di DNA
ko-KR Korean (Korea, Republic Of) 거대세포바이러스 디옥시리보핵산:임의농도:검사시점:전혈:순위척도:DNA 탐색자.증폭.sig
nl-NL Dutch (Netherlands) Cytomegalovirus DNA:aanwezigheid:moment:bloed:ordinaal:probe.amp.sig
pt-BR Portuguese (Brazil) Citomegalovírus DNA:ACnc:Pt:SgTotal:Ord:Sonda com amplificação de sinal
Synonyms: Deoxyribonucleic acid; CMV; Cytomgal; Cytomegalo virus; Arbitrary concentration; Point in time; Random; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; bDNA; HPA; Hybidization Protection Assay; Bdn-A; Branched Chain DNA; Hybrid Capture; Probe with signal amplification; Hybrid Capture nucleic acid hybridization; HC; Amp Prb; Probe with ampification; DNA probe; Amplification; Amplified; Microbiology
ru-RU Russian (Russian Federation) Цитомегаловирус ДНК:PrThr:ТчкВрм:Кр:Пор:Проба.усил.сигн
Synonyms: ДНК проба;ДНК зонд Кровь Порядковый Проба с сигнала усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus DNA:MevcEşik:Zmlı:Kan:Srl:Prob.amf.siny
Synonyms: Mevcut
uk-UA Ukrainian (Ukraine) Цитомегаловірус ДНК:Наявність або Поріг:МоментЧасу:Кров:Порядково:Зонд-детекція. підсилення сигналу
Synonyms: Amplif; Amplification; Amplified; bDNA; Bdn-A; Blood; Branched Chain DNA; CMV; Cytomegalo virus; Cytomgal; Deoxyribonucleic acid; DNA NUCLEIC ACID PROBE; DNA probe; HC; HHV-5; HPA; Human Herpesvirus-5; Hybidization Protection Assay; Hybrid Capture; Hybrid Capture nucleic acid hybridization; ID; Infectious Disease; InfectiousDisease; Microbiology; Ordinal; Point in time; PR; Probe amp; Probe with ampification; Probe with signal amplification; Probe+sig amp; Ql; Qual; Qualitative; Random; Screen; UniversalLabOrders; WB; Whole blood
zh-CN Chinese (China) 巨细胞病毒 DNA:存在情况或阈值:时间点:全血:序数型:探针法.基因扩增.信号
Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助信号扩增的探针方法;借助信号扩增的探针法;探针法.扩增.信号;支链 DNA;支链 DNA(Branched Chain DNA,bDNA);杂交保护分析;杂交保护分析(Hybidization Protection Assay,HPA);杂交保护测定;杂种捕获;杂种捕获(Hybrid Capture);杂种捕获核酸杂交(Hybrid Capture nucleic acid hybridization) 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸(Deoxyribonucleic acid,DNA) 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=28008-1