Version 2.80

Term Description

Ki-67 is a proliferation marker that correlates with flow cytometric S-phase. Breast cancer specimens with greater than 20% Ki-67 positivity will generally have a high S-phase fraction, which is an unfavorable prognostic marker.

Part Description

LP247969-1   Cells.Ki-67 nuclear
Ki-67 nuclear antigen is a marker of cell proliferation. In breast cancer specimens, the degree of Ki-67 staining, assessed using MIB-1, a monoclonal antibody, is associated with the degree of proliferation. In general, tumors with higher degrees of proliferation are associated with worse prognosis. While the baseline degree of Ki-67 staining may not be predictive, the change in the proportion of Ki-67 positive cells before and after therapy may be predictive of disease-free and overall survival. PMID: 23280579 Source: Regenstrief LOINC

Fully-Specified Name

Component
Cells.Ki-67 nuclear Ag/Cells
Property
NFr
Time
Pt
System
Tiss
Scale
Qn
Method
Immune stain

Additional Names

Long Common Name
Cells.Ki-67 nuclear Ag/cells in Tissue by Immune stain
Short Name
Ki-67 nuclear Ag NFr Tiss ImStn
Display Name
Cells.Ki-67 nuclear Ag/cells Immune stain (Tiss)
Consumer Name Alpha Get Info
Cells.Ki-67 Nuclear/cells, Tissue

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.03
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component; Previous Releases: Updated Component from "MIB-1 Ag" by adding "Cells." to correctly represent that a number fraction is being reported, and changed "MIB-1" to "Ki-67 nuclear", because MIB-1 is the monoclonal antibody that detects the Ki-67 antigen and MIB-1 itself is not the antigen
Order vs. Observation
Both
Common Test Rank Get Info
12486

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κύτταρα.Ki-67 πυρηνικά Αντιγόνο/κύτταρα:NFr:Pt:Ιστός:Qn:Ανοσολογική χρώση
Synonyms: NFr
es-AR Spanish (Argentina) antígeno de MIB1/100 células:fracción de un número:punto en el tiempo:tejido, no especificado:cuantitativo:tinción inmunológica
es-ES Spanish (Spain) Células.ki-67 nuclear Antígeno/células:Fracción numérica:Punto temporal:Tejido:Qn:Tinción de inmunohistoquímica
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cells.Ki-67 nuclear Ag / 100 células:Fracción numérica:Punto temporal:Tejido y frotis:Cuantitativo:Mancha inmune
fr-CA French (Canada) Cellules.Ki-67 nucléaire, Ag/Cellules:Fraction numérique:Temps ponctuel:Tissu:Quantitatif:Coloration immunologique
fr-FR French (France) Ki-67 antigène/100 cellules:Fraction de nombres:Ponctuel:Tissu:Numérique:Coloration immune
it-IT Italian (Italy) Cellule.Ki.67 nucleare, Ag/cellule:NFr:Pt:Tessuto:Qn:Colorazione immunologica
Synonyms: Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) MIB-1 항원/100 세포:숫자분획:검사시점:조직:정량:면역염색
nl-NL Dutch (Netherlands) cellen.Ki-67 nucleair Ag/cellen:getalsfractie:moment:weefsel en uitstrijkjes:kwantitatief:immunokleuring
Synonyms: antigeen
pl-PL Polish (Poland) Komórki.jądrowy Ki-67 Ag/komórki:frakcja liczbowa:punkt w czasie:tkanka i rozmazy:ilościowy:barwnik immunologiczny
Synonyms: Antygen jądrowy Ki-67 Antygen jądrowy Ki-67 w komórce barwnik immunologiczny Jądrowy Ki-67 w komórce Jądrowy marker proliferacji komórkowej Ki-67
pt-BR Portuguese (Brazil) MIB-1 Ag/100 células:NFr:Pt:Tecido:Qn:Imunocoloração
Synonyms: KI-67; Mindbomb homolog 1; Cell; Cellularity; Gated cells; Fr; Number fraction; Percent; Point in time; Random; Tissue; Quantitative; QNT; Quant; Quan; ImStn; Immunostain; Immunohistochemical stain; IHC; Antigen; Antigens; Imun; Imune; Imm; I; CELL MARKERS
zh-CN Chinese (China) 细胞.Ki-67 细胞核 抗原/细胞:计数型分数:时间点:组织与涂片:定量型:免疫染色法
Synonyms: Ag Ki-67 胞核;Ki-67 核;KI-67;MIB1;MIB-1;MIB-1 是一个与流式细胞术 S-期相关的增殖标志物。MIB-1 阳性率大于20%的乳腺癌标本一般都具有高的 S-期分数，而这是一种不利的预后标志物。;Mindbomb 同源基因 1;智能弹同源基因 1;Mindbomb homolog 1 MIB-1 Ag Mindbomb 同源基因 1 Ag Mindbomb 同源基因 1 抗原 免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 智能弹同源基因 1 Ag 智能弹同源基因 1 抗原 未作说明的组织;组织;组织 & 涂片 染法 染色方法 染色法 核;胞核 着色 着色方法 着色法 细胞.Ki-67 细胞核（胞核、核） 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29593-1