Version 2.80

Part Description

LP18407-4   2-Oxo,3-Methylvalerate
3-Methyl-2-oxovaleric acid is a metabolite of isoleucine in man, animals and bacteria. It is the alpha-keto acid analogue of isoleucine. 3-Methyl-2-oxovaleric acid is produced from isoleucine by cytosolic branched chain aminotransferase 1 (EC:2.6.1.42), whereupon it is further degraded by branched chain keto acid dehydrogenase E1 to 2-Methyl-1-hydroxybutyl-ThPP. It is used as a clinical marker for maple syrup urine disease (MSUD). MSUD is caused by a deficiency of the branched-chain -keto acid dehydrogenase compex resulting in an accumulation of branched-chain amino acids and the corresponding -keto-and -hydroxy acids in blood, urine and cerebrospinal fluid causing neurological damage and mental retardation. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database , 2-Oxo,3-Methylvalerate

Fully-Specified Name

Component
2-Oxo,3-Methylvalerate
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method

Additional Names

Long Common Name
2-Oxo,3-Methylvalerate [Presence] in Urine
Short Name
2Oxo3Me-valerate Ur Ql
Display Name
2-Oxo,3-Methylvalerate Ql (U)
Consumer Name Alpha Get Info
2-Oxo,3-Methylvalerate, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.04
Last Updated
Version 2.73 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
9051

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) 3-μεθυλο-2-οξο-βαλερικό οξύ:PrThr:Pt:Ούρα:Ord:
Synonyms: PrThr
es-AR Spanish (Argentina) 2-oxo,3-metilvalerato:concentración arbitraria:punto en el tiempo:orina:ordinal:
es-ES Spanish (Spain) 2-Oxo,3-Metilvalerato:PrThr:Punto temporal:Orina:Ord:
es-MX Spanish (Mexico) 2-oxo, 3-metilvalerato:Presencia o umbral:Punto temporal:Orina:Ordinal:
fr-CA French (Canada) 2-oxo,3-méthylvalérate:Présence-Seuil:Temps ponctuel:Urine:Ordinal:
fr-FR French (France) 2-oxo-3-méthylvalérate:Présence/Seuil:Ponctuel:Urine:Qualitatif:
fr-BE French (Belgium) 2-oxo,3-méthylvalérate:PrThr:Temps ponctuel:Urine:Ordinal:
it-IT Italian (Italy) 2-Osso,3-Metilvalerato:PrThr:Pt:Urine:Ord:
Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio)
ko-KR Korean (Korea, Republic Of) 2-옥소,3-메틸발레레이트:임의농도:검사시점:뇨:순위척도:
nl-NL Dutch (Netherlands) 2-oxo,3-methylvaleraat:aanwezigheid:moment:urine:ordinaal:
pt-BR Portuguese (Brazil) 2-Oxo,3-Metilvalerato:ACnc:Pt:Urina:Ord:
Synonyms: ; 2Oxo3Me-valerate; 2-keto-3-methylvaleric acid; 2-keto-3-methylvalerate; 2-oxo,3-methylvaleric acid; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Ql; Ordinal; QL; Qualitative; Qual; Screen; III; II; Chemistry
ru-RU Russian (Russian Federation) 2-Оксо,3-Метилвалерат:PrThr:ТчкВрм:Моча:Пор:
Synonyms: Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) 2-Okzo,3-Metilvalerat:MevcEşik:Zmlı:İdrar:Srl:
Synonyms: Mevcut
zh-CN Chinese (China) 2-氧代,3-甲基戊酸:存在情况或阈值:时间点:尿液:序数型:
Synonyms: 2Oxo3Me-戊酸;2-酮-3-甲基戊酸;2-酮基-3-甲基戊酸 Ⅱ Ⅲ II III 三 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 尿;小便;下泉 时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29864-6