3013-0
Thyroglobulin [Mass/volume] in Serum or Plasma
Active
Part Descriptions
LP14697-4 Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease.
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Source: Wikipedia, Thyroglobulin (Wikipedia)
LP14697-4 Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. PMID: 9543128
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Thyroglobulin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Thyroglob SerPl-mCnc
- Display Name
- Thyroglobulin [Mass/Vol]
- Consumer Name Alpha Get Info
- Thyroglobulin, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 729
Member of these Panels
LOINC | Long Common Name |
---|---|
57780-9 | Thyroglobulin and Thyroglobulin Ab panel - Serum or Plasma |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG49663-4 | Thyroglobulin| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Thyreoglobulin: Synonyms: hTG |
de-AT | German (Austria) | Synonyms: Thyreoglobulin |
el-GR | Greek (Greece) | Θυρεοσφαιρίνη: |
es-MX | Spanish (Mexico) | Tiroglobulina: |
es-ES | Spanish (Spain) | Tiroglobulina: Synonyms: Cuantitativo |
es-AR | Spanish (Argentina) | tiroglobulina: |
et-EE | Estonian (Estonia) | Türeoglobuliin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Thyroglobuline: |
fr-FR | French (France) | Thyroglobuline: |
fr-BE | French (Belgium) | Thyroglobuline: Synonyms: hTG |
it-IT | Italian (Italy) | Tireoglobulina: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 갑상샘글로불린: |
nl-NL | Dutch (Netherlands) | thyreoglobuline: |
pt-BR | Portuguese (Brazil) | Tireoglobulina: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Тиреоглобулин: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Tiroglobulin: |
uk-UA | Ukrainian (Ukraine) | Тиреоглобулін: Synonyms: Chemistry; |
zh-CN | Chinese (China) | 甲状腺球蛋白: Synonyms: TG; |
Example Units
Unit | Source |
---|---|
ng/dL | Example UCUM Units |
ng/dL | REGENSTRIEF |
ng/mL | REGENSTRIEF |
ug/L | eCHN |
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