31092-0
Gentamicin [Mass/volume] in Serum or Plasma --trough post extended interval dosing
Active
Part Descriptions
LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275]
Source: Regenstrief LOINC
LP29304-0 trough post extended interval dosing
Extended interval (once daily) dosing of aminoglycosides may be less nephrotoxic than conventional dosing methods.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Gentamicin^trough post extended interval dosing
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Gentamicin [Mass/volume] in Serum or Plasma --trough post extended interval dosing
- Short Name
- Gentamicin Trough EID SerPl-mCnc
- Display Name
- Gentamicin trough post extended interval dosing [Mass/Vol]
- Consumer Name Alpha Get Info
- Gentamicin trough after Extended Interval Dosing, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.07
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 10956
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Γενταμυκίνη^ελάχιστα επίπεδα κατόπιν δόσης παρατεταμένου διαστήματος: Synonyms: MCnc Γενταμυκίνη |
es-AR | Spanish (Argentina) | gentamicina^concentración mínima [valle] después de la prolongación del intervalo de dosificación: |
es-ES | Spanish (Spain) | Gentamicina^Valle pos dosificación de aminoglucósidos en intervalo extendido o monodosis: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Gentamicina ^ mínimo después de la administración de intervalos prolongados: |
fr-CA | French (Canada) | Gentamicine^Creux post dose intervalle prolongé: |
fr-FR | French (France) | Gentamicine taux résiduel après un intervalle posologique allongé: |
fr-BE | French (Belgium) | Gentamicine^Creux post dose intervalle prolongé: Synonyms: Minimum, nadir |
it-IT | Italian (Italy) | Gentamicina^valore minimo post esteso intervallo di dosaggio: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Valore minimo dopo esteso intervallo di dosaggio d valore minimo TDM |
ko-KR | Korean (Korea, Republic Of) | 겐타마이신^연장 간격 투여 후 최저 약물 농도 시간: |
nl-NL | Dutch (Netherlands) | gentamicine^dalspiegel na langdurige intervaldosering: |
pt-BR | Portuguese (Brazil) | Gentamicina^basal antes da administração da próxima dose: Synonyms: c213; |
ru-RU | Russian (Russian Federation) | Гентамицин^спад после расширения интервала дозирования: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Gentamisin^genişletilmiş ara dozdan sonraki en düşük düzey: |
zh-CN | Chinese (China) | 庆大霉素^在延长时间间隔剂量给药之后的波谷: Synonyms: EID XXX刺激 - 在...之后 一剂药物的初始剂量; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
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