32283-4

Valproate Free/Valproate.total in Serum or Plasma

Active

Part Description

LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Valproate.free/Valproate.total:MFr:Pt:Ser/Plas:Qn:
Long Common Name: Valproate Free/Valproate.total in Serum or Plasma
Short Name: Valproate Free MFr SerPl
Display Name: Valproate Free/Total valproate [Mass fraction]
Consumer Name Alpha Get Info: Free valproate/Valproate.total, Blood

Part Model Get Info

Component
Valproate.free/Valproate.total
LP287356-2
- Analyte
  Valproate.free/Valproate.total
  LP287356-2
  - Component Numerator
    Valproate.free
    LP29130-9
    - Component Numerator Core
      Valproate.free
      LP29130-9
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Valproate.total
    LP32177-5
    - Component Denominator Core
      Valproate.total
      LP32177-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MFr
LP6831-4
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.07
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Observation
Common Test Rank Get Info: 5529

Member of these Panels

LOINC	Long Common Name
54037-7	HEDIS 2009 panel
57820-3	HEDIS 2010 panel
60442-1	HEDIS 2011 panel
67767-4	HEDIS 2012 panel
72199-3	HEDIS 2013 panel
74234-6	HEDIS 2014 Value Sets

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Valproát.volný/valproát.celkový:Hmotnostní podíl:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Βαλπροϊκό.ελεύθερο/Βαλπροϊκό οξύ.ολικό:MFr:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX MFr Pt Qn Βαλπροϊκό οξύ Βαλπροϊκό οξύ.ολικό Βαλπροϊκό.ελεύθερο Ορός Ορός/Πλάσμα Πλάσμα
es-AR	Spanish (Argentina)	valproato.libre/valproato.total:fracción de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES	Spanish (Spain)	Valproico libre/Valproato total:Fracción de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Valproato.libre/Valproato.total:Fracción de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	Valproaat.vaba/valproaat.üld:MFr:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Valproate.libre/Valproate.totale:Fraction de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Valproate libre/valproate total:Fraction massique:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Valproate.libre/Valproate.totale:Fraction de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Valproato.libero/Valproato.totale:MFr:Pt:Siero/Plasma:Qn: Synonyms: Frazione di massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Valproato Libero
ko-KR	Korean (Korea, Republic Of)	유리벨프로에이트/총벨프로에이트:질량분획:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	valproaat.vrije/valproaat.totaal:massafractie:moment:serum of plasma:kwantitatief: Synonyms: valproinezuur; 2-propylpentaanzuur
pt-BR	Portuguese (Brazil)	Valproato.livre/Valproato.total:MFr:Pt:Sor/Plas:Qn: Synonyms: Valproic acid; Depakene; Mass fraction; Percent; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; Tot; Totl; FR; Non-protein bound; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Вальпроат.свободный/Вальпроат.общий:МассДол:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая доля Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Valproat.serb/Valproat.total:KütlFr:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	2-丙基戊酸.游离型/2-丙基戊酸.总计:质量分数:时间点:血清/血浆:定量型: Synonyms: 2-丙基戊酸.游离;游离 2-丙基戊酸;游离型 2-丙基戊酸 2-丙基戊酸总计 2-丙基戊酸钠;C8H15NaO2;丙基戊酸;丙戊酸;VPA;Valproate;Valproic Acid MFr 全体数量全部共计可用数量表示的;定量性;数值型;数量型;连续数值型标尺总总和总数总量总额时刻;随机;随意;瞬间毒品毒品类汇总游离药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆非蛋白结合型非蛋白质结合型

Example Units

Unit	Source
%	Example UCUM Units
%	REGENSTRIEF

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=32283-4

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.