34547-0
Complement profile panel [Mass/volume] - Serum or Plasma
Active
4485-9 Complement C3 [Mass/volume] in Serum or Plasma
Part Descriptions
LP16359-9 Complement C3
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement C3 is involved in the activation of both the classical and alternate complement pathways. It is the most concentrated of the complement members and is composed of 5 subunits: C3a, C3b, C3c, C3d and C3 d. Decreased levels of C3 is associated with disease inactivation in systemic lupus erythematosus (SLE) and may also be associated with acute glomerulonephritis, immune complex disease, septic shock, and end-stage liver disease. PMID: 6433145 PMID: 3295544 Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency.
Source: Regenstrief Institute
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Complement C3
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- C3 SerPl-mCnc
- Display Name
- Complement C3 [Mass/Vol]
- Consumer Name Alpha Get Info
- Complement C3, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 448
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 34544-7 | Complement C3 and C4 panel [Mass/volume] - Serum or Plasma |
| 34547-0 | Complement profile panel [Mass/volume] - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Komplement C3: Synonyms: C3c |
| el-GR | Greek (Greece) | C3 παράγοντας συμπληρώματος: |
| es-AR | Spanish (Argentina) | fracción C3 del complemento: |
| es-ES | Spanish (Spain) | Complemento C3: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Complemento C3: |
| et-EE | Estonian (Estonia) | Komplemendi komponent C3: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Complément C3: |
| fr-FR | French (France) | Complément C3: |
| fr-CA | French (Canada) | Complément C3: |
| it-IT | Italian (Italy) | Complemento C3: Synonyms: Concentrazione di Massa Ematologia (coagulazione) conta differenziale Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 도움체 C3: |
| nl-NL | Dutch (Netherlands) | complement C3: |
| pt-BR | Portuguese (Brazil) | Complemento C3: Synonyms: Beta 1 C-globulin; |
| ru-RU | Russian (Russian Federation) | Комплемент С3: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Kompleman C3: |
| uk-UA | Ukrainian (Ukraine) | Комплемент C3: Synonyms: Beta 1 C-globulin; |
| zh-CN | Chinese (China) | 补体 C3: Synonyms: 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| mg/dL | Example UCUM Units |
| mg/dL | REGENSTRIEF |
4498-2 Complement C4 [Mass/volume] in Serum or Plasma
Part Descriptions
LP16371-4 Complement C4
A glycoprotein important in the activation of the classical complement pathway. It is cleaved by the activated component C1S into C4A and C4B.
Source: National Library of Medicine, MeSH 2006
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Complement C4
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- C4 SerPl-mCnc
- Display Name
- Complement C4 [Mass/Vol]
- Consumer Name Alpha Get Info
- Complement C4, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 439
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 34544-7 | Complement C3 and C4 panel [Mass/volume] - Serum or Plasma |
| 34547-0 | Complement profile panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG43109-4 | Complement C4| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Komplement C4: |
| de-AT | German (Austria) | Synonyms: C4 Komplement |
| el-GR | Greek (Greece) | C4 παράγοντας συμπληρώματος: |
| es-AR | Spanish (Argentina) | fracción C4 del complemento: |
| es-ES | Spanish (Spain) | Proteina C4 del complemento: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Complemento C4: |
| et-EE | Estonian (Estonia) | Komplemendi komponent C4: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Complément C4: |
| fr-CA | French (Canada) | Complément C4: |
| fr-FR | French (France) | Complément C4: |
| it-IT | Italian (Italy) | Complemento C4: Synonyms: Concentrazione di Massa Ematologia (coagulazione) conta differenziale Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 도움체 C4: |
| nl-NL | Dutch (Netherlands) | complement C4: |
| pt-BR | Portuguese (Brazil) | Complemento C4: Synonyms: Beta 1 E-globulin; |
| ru-RU | Russian (Russian Federation) | Комплемент C4: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Kompleman C4: |
| uk-UA | Ukrainian (Ukraine) | Комплемент C4: Synonyms: Beta 1 E-globulin; |
| zh-CN | Chinese (China) | 补体 C4: Synonyms: Beta 1 E-球蛋白 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| mg/dL | Example UCUM Units |
| mg/dL | REGENSTRIEF |
30131-7 Complement total hemolytic CH50 [Mass/volume] in Serum or Plasma
Part Descriptions
LP29040-0 Complement total hemolytic CH50
Complement total hemolytic CH50 testing is used to monitor Systemic Lupus Erythematosus (SLE) patients' response to therapy. It is also used to evaluate complement component deficiency, complement activity in patients with immune complexes , glomerulonephritis, rheumatoid arthritis, and cryoglobulinemia. Complement is a system of 25 proteins associated with cell membranes and present in plasma; it plays a vital role in the function of the immune system. Complement components function in the "classical" and "alternative" pathways. The CH50 assay mainly evaluates the classical pathway. Complement proteins are activated during the acute phase of inflammation or infection. Decreased levels of complement components occur during hypercatabolism, expenditure in immune complexes or due to hereditary deficiency. Decreasing complement levels may signal upcoming clinical problems, especially lupus nephritis.
Source: Regenstrief Institute
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Complement total hemolytic CH50
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- CH50 SerPl-mCnc
- Display Name
- Complement total hemolytic CH50 [Mass/Vol]
- Consumer Name Alpha Get Info
- Complement Total Hemolytic CH50, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.04
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 19099
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 34547-0 | Complement profile panel [Mass/volume] - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Komplement Gesamthämolytisch CH50: |
| el-GR | Greek (Greece) | Ολικό αιμολυτικό συμπλήρωμα CH50: |
| es-ES | Spanish (Spain) | Complemento hemolitico total CH50: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | complemento hemolítico total CH50: |
| es-MX | Spanish (Mexico) | Complemento de CH50 hemolítico total: |
| et-EE | Estonian (Estonia) | Komplemendi klassikalise tee aktiivsus CH50 seerumis: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Hémolyse CH50: |
| fr-FR | French (France) | Complément total hémolytique CH50: |
| fr-CA | French (Canada) | Complément hémolytique total CH50: |
| it-IT | Italian (Italy) | Complemento emolitico totale CH50: Synonyms: Concentrazione di Massa Ematologia (coagulazione) conta differenziale Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 도움체 총 용혈 CH50: |
| nl-NL | Dutch (Netherlands) | complement totaal hemolytisch CH50: |
| pt-BR | Portuguese (Brazil) | Complemento total hemolitico CH50: Synonyms: Complement CH50; |
| ru-RU | Russian (Russian Federation) | Комплемент общий гемолитический CH50: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Kompleman total hemolitik CH50: |
| zh-CN | Chinese (China) | 补体总溶血活性 Ch50: Synonyms: 全体数量 全部 共计 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| mg/dL | Example UCUM Units |