34915-9

Malignant cells/Leukocytes in Blood

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Part Descriptions

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LP31549-6   Malignant cells
In medicine, malignant is a clinical term that is used to describe a clinical course that progresses rapidly to death. It is typically applied to neoplasms that show aggressive behavior characterised by local invasion or distant metastasis. The change of cells from benign to malignant behavior is called malignant transformation. Usually this diagnosis is made by pathologic examination of tissues. However, often the physician during the history and physical examination can find that there have been changes in size or patient sensation and upon direct examination that there has been a change in the lesion itself. Malignant transformation is a synonym for progression to malignancy. Transformation may take place as a primary or a secondary process. Although malignant transformation may occur because of changes within the cell, it can be induced by inorganic toxic substances such as cadmium or arsenite and organics such as tobacco-specific nitrosamines. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Malignant cells (Wikipedia)

LP31549-6   Malignant cells
A neoplasm which invades serous cavities can cause malignant cells to be seen in body fluid specimens. The cells have increased cell and nuclear size, irregularly shaped nuclei, large nucleoli, high nuclear to cytomplasmic ratio, and atypical nuclear chromatin patterns. The cells can be numerous or rarely seen; some can form large clusters. Source: 2010 Hematology and Clinical Microscopy Glossary by College of Americal Pathologists (CAP). Source: Regenstrief Institute

Fully-Specified Name

Component

Malignant cells/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Additional Names

Long Common Name

Malignant cells/Leukocytes in Blood

Short Name

Malignant cells NFr Bld

Display Name

Malignant cells/Leukocytes (Bld)

Consumer Name Alpha Get Info

Malignant cells/White Blood Cells, Blood

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 2.11

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Member of these Panels

Language Variants Get Info

Related Names

• Blood
• Cell
• Cellularity
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Malig
• Number fraction
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=34915-9

LOINC Copyright

Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.