14976-5 Lecithin/Sphingomyelin [Ratio] in Amniotic fluid

Part Descriptions

LP15697-3   Lecithin
Lecithin belongs to a group of yellow-brownish fatty substances occurring in animal and plant tissues, and in egg yolk. It is composed of phosphoric acid, choline, fatty acids, glycerol, glycolipids, triglycerides, and phospholipids (e.g., phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol). Lecithin is sometimes used as a synonym for pure phosphatidylcholine, a phospholipid that is the major component of its phosphatide fraction. Lecithin may be isolated either from egg yolk or from soy beans. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Lecithin

LP15697-3   Lecithin
Lecithin naturally occurs in plants and animals. It is composed of glycerol, two fatty acids, a phosphate group, and choline.Lecithin is found in many foods including egg yolks, liver, peanuts, corn, spinach, whole grains, and soy beans.Lecithin is used commercially as an emulsifier in baking mixes, candy, chewing gum, chocolate, ice cream, macaroni, margarine, whipped toppings, and many more.Lecithin in the body is present in bile and functions to help emulsify dietary fats in the lumen of the small intestine. Bile is produced in the liver and stored and concentrated in the gallbladder.
Lecithin is a the most abundant phospholipid that makes up the majority of cellular membranes. Lecithin mixes with oil and water to form micelles.Micelles are spherical shells of fat surounded by lecithin.The nonpolar tails are oriented inward toward the fat and the polar end of lecithin is oriented outward toward the water.The formation of micelles is a mechanical process known as emulsification which breaks fat into small droplets and makes the droplets water soluble.[books.google.com/books?id=bmIMBAAAQBAJ&pg=PA912&lpg=PA912&dq=lecithin+physiology&source=bl&ots=yIbPL5YMWy&sig=WX7E1RPt3q8G7hIehF9ASo3StM0&hl=en&sa=X&ved=0ahUKEwiYusmvvKDWAhWm0YMKHYt7CsgQ6AEISDAJ#v=onepage&q=lecithin%20physiology&f=false][http://science.jrank.org/pages/3881/Lecithin-Dietary-commercial-sources.html] Source: Regenstrief LOINC

LP32157-7   Sphingomyelin
Sphingomyelin is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath which surrounds some nerve cell axons. Like all sphingolipids, it consists of sphingosine bonded to one fatty acid and one polar head group, which, in sphingomyelins, is either phosphocholine or phosphoethanolamine. The fatty acid is attached to the second carbon of sphingosine via an amide linkage. The function of sphingomyelin remained unclear until recently when it was found to have a function in signal transduction. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Sphingomyelin (Wikipedia)

Observation Required in Panel

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Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Lecithin/Sphingomyelin

Property

Ratio

Time

Pt

System

Amnio fld

Scale

Qn

Method

Additional Names

Short Name

Lecithin/Sphingomyelin Amn-Rto

Display Name

Lecithin/Sphingomyelin (Amn fld) [Ratio]

Consumer Name Alpha Get Info

Lecithin/Sphingomyelin, Amniotic fluid

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

11905

Member of these Panels

Language Variants Get Info

Related Names

• AF
• Amn
• Amn fl
• Amnio
• Amniotic flu
• Amniotic fluid
• c470
• Chemistry
• Choline phosphoglyceride
• Phosphatidylcholine
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Ratios
• Rto
• SPH
• UniversalLabOrders

Example Units

2785-4 Phosphatidylglycerol [Presence] in Amniotic fluid

Part Descriptions

LP15798-9   Phosphatidylglycerol
Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant.
The general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2. The head group substituent glycerol is bonded through a phosphomonoester. It is the precursor of surfactant and its presence in the amniotic fluid of the newborn indicates fetal lung maturity.
Approximately 98% of alveolar wall surface area is due to the presence of type I cells, with type II cells producing pulmonary surfactant covering around 2% of the alveolar walls. Once surfactant is secreted by the type II cells, it must be spread over the remaining type I cellular surface area. Phosphatidylglycerol is thought to be important in spreading of surfactant over the Type I cellular surface area. The major surfactant deficiency in premature infants is associated with the lack of phosphatidylglycerol, even though it comprises less than 5% of pulmonary surfactant phospholipids. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Phosphatidylglycerol

Observation Required in Panel

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Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Phosphatidylglycerol

Property

PrThr

Time

Pt

System

Amnio fld

Scale

Ord

Method

Additional Names

Short Name

PG Amn Ql

Display Name

Phosphatidylglycerol Ql (Amn fld)

Consumer Name Alpha Get Info

Phosphatidylglycerol, Amniotic fluid

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

10582

Member of these Panels

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Related Names

• AF
• Amn
• Amn fl
• Amnio
• Amniotic flu
• Amniotic fluid
• Chemistry
• Fetal lung maturity
• Ordinal
• PG
• Phosphatidyl Glycerol
• Phosphotidylglycerol
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen

47226-6 Fetal lung maturity [Interpretation] in Amniotic fluid

Part Descriptions

LP33021-4   Fetal lung maturity
The ability of an infant to survive outside the uterus is dependent on proper pulmonary function. Pulmonary surfactant is needed to reduce the surface tension of the air-liquid interface of the alveolar lining, so that alveoli do not collapse upon expiration. Infants born with a deficiency of pulmonary surfactant are at increased risk of developing respiratory distress syndrome (RDS). The incidence of RDS is dependent on the gestational age, with more RDS occurring in younger fetuses. Source: Regenstrief Institute

Observation Required in Panel

Optional

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Fetal lung maturity

Property

Imp

Time

Pt

System

Amnio fld

Scale

Nom

Method

Additional Names

Short Name

FLM Amn-Imp

Display Name

Fetal lung maturity (Amn fld) [Interp]

Consumer Name Alpha Get Info

Fetal lung maturity, Amniotic fluid

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.19

Last Updated

Version 2.73

Order vs. Observation

Observation

Member of these Panels

Language Variants Get Info

Related Names

• AF
• Amn
• Amn fl
• Amnio
• Amniotic flu
• Amniotic fluid
• Chemistry
• Fetal lung maturity
• FLM
• Impression
• Impression/interpretation of study
• Impressions
• Interp
• Interpretation
• Nominal
• Point in time
• Random