Version 2.80

Part Description

LP16444-9   Hemoglobin Lepore
Hemoglobin Lepore syndrome or Hb Lepore syndrome (Hb Lepore) is typically an asymptomatic hemoglobinopathy, which is caused by an autosomal recessive genetic mutation. The Hb Lepore variant, consisting of two normal alpha globin chains (HBA) and two deltabeta globin fusion chains which occurs due to a "crossover" between the delta (HBD) and beta globin (HBB) gene loci during meiosis.

The homozygous state for Hb Lepore is rare. Patients of Balkan descent tend to have the most severe presentation of symptoms including severe anemia during the first five years of life. They also presented with significant splenomegaly, hepatomegaly, and skeletal abnormalities identical to those of homozygous beta-thalassemia. The amount of Hb Lepore in the patients blood ranged from 8 to 30 %, the remainder being fetal hemoglobin (Hb F) which is present in minute quantities (typically<1 percent) in the red blood cells of adults. Known as F- cells they are present in a small proportion of overall RBCs.

Heterozygous Hb Lepore is similar to beta-thalassemia major, however the clinical course is variable. Patients with this condition typically present with severe anemia during the first two years of life. The heterozygote form is mildly anemic (Hb 11-13 g/dl) but presents with a significant hypochromia (deficiency of hemoglobin in the red blood cells) and microcytosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

Fully-Specified Name

Component
Hemoglobin Lepore/Hemoglobin.total
Property
MFr
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Long Common Name
Hemoglobin Lepore/Hemoglobin.total in Blood
Short Name
Hgb Lepore MFr Bld
Display Name
Hemoglobin Lepore (Bld) [Mass fraction]
Consumer Name Alpha Get Info
Hemoglobin lepore/Total Hgb, Blood

Basic Attributes

Class
HEM/BC
Type
Laboratory
First Released
Version 2.11
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Observation
Common Test Rank Get Info
11897

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Αιμοσφαιρίνη Lepore/Αιμοσφαιρίνη.ολική:MFr:Pt:Αίμα:Qn:
Synonyms: MFr Αιμοσφαιρίνη Αιμοσφαιρίνη Lepore
es-AR Spanish (Argentina) HEMOGLOBIN LEPORE:fracción de masa:punto en el tiempo:sangre:cuantitativo:
es-ES Spanish (Spain) Hemoglobina Lepore/Hemoglobina.total:Fracción de masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Hemoglobina Lepore / Hemoglobina total:Fracción de masa:Punto temporal:Sangre:Cuantitativo:
fr-CA French (Canada) Hémoglobine Lepore/Hémoglobine.totale:Fraction de masse:Temps ponctuel:Sang:Quantitatif:
fr-FR French (France) Hémoglobine Lepore/hémoglobine totale:Fraction massique:Ponctuel:Sang:Numérique:
fr-BE French (Belgium) Hémoglobine Lepore/Hémoglobine.totale:Fraction de masse:Temps ponctuel:Sang:Quantitatif:
Synonyms: Hb Hb Lepore Hb.totale
it-IT Italian (Italy) Emoglobina Lepore/Emoglobina.totale:MFr:Pt:Sangue:Qn:
Synonyms: Ematologia (coagulazione) conta differenziale Frazione di massa Punto nel tempo (episodio) Sangue
ko-KR Korean (Korea, Republic Of) 르포르 혈색소/총혈색소:질량분획:검사시점:전혈:정량:
nl-NL Dutch (Netherlands) hemoglobine Lepore/hemoglobine.totaal:massafractie:moment:bloed:kwantitatief:
pl-PL Polish (Poland) Hemoglobina Lepore/hemoglobina całkowita:frakcja masowa:punkt w czasie:krew:ilościowy:
Synonyms: Hemoglobina Hasharon''a/Hemoglobina całkowita
pt-BR Portuguese (Brazil) Hemoglobina Lepore/Hemoglobina.total:MFr:Pt:SgTotal:Qn:
Synonyms: ; Hgb Lepore; Hb; Haemoglobin; Mass fraction; Percent; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Tot; Totl; HEMATOLOGY/CELL COUNTS; HEMATOLOGY/CELL COUNTS
ru-RU Russian (Russian Federation) Гемоглобин Lepore/Гемоглобин.общий:МассДол:ТчкВрм:Кр:Колич:
Synonyms: Количественный Кровь Массовая доля Точка во времени;Момент
tr-TR Turkish (Turkey) Hemoglobin Lepore/Hemoglobin.total:KütlFr:Zmlı:Kan:Kant:
zh-CN Chinese (China) 血红蛋白 Lepore/血红蛋白.总计:质量分数:时间点:全血:定量型:
Synonyms: Hgb Lepore MFr 全体数量 全部 共计 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 总 总和 总数 总血红蛋白 总量 总额 时刻;随机;随意;瞬间 氧血红蛋白;血红朊;血红素;血色素 汇总 血;血液 血液学/细胞计数;血液学与细胞计数

Example Units

Unit Source
% Example UCUM Units

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=35125-4