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Part Description

LP17270-7   Dirithromycin
Dirithromycin is a macrolide glycopeptide antibiotic.

Dirithromycin (Dynabac) is a more lipid-soluble prodrug derivative of 9S-erythromycyclamine prepared by condensation of the latter with 2-(2-methoxyethoxy)acetaldehyde. The 9N, 11O-oxazine ring thus formed is a hemi-aminal that is unstable under both acidic and alkaline aqueous conditions and undergoes spontaneous hydrolysis to form erythromycyclamine. Erythromycyclamine is a semisynthetic derivative of erythromycin in which the 9-ketogroup of the erythronolide ring has been converted to an amino group. Erythromycyclamine retains the antibacterial properties of erythromycin oral administration. The prodrug, dirithromycin, is provided as enteric coated tablets to protect it from acid catalyzed hydrolysis in the stomach. Orally administered dirithromycin is absorbed rapidly into the plasma, largely from the small intestine. Spontaneous hydrolysis to erythromycyclamine occurs in the plasma. Oral bioavailability is estimated to be about 10%, but food does not affect absorption of the prodrug. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
Dirithromycin:Susc:Pt:Isolate:OrdQn:Agar diffusion
Long Common Name
Dirithromycin [Susceptibility] by Disk diffusion (KB)
Short Name
Dirithromycin Islt KB
Display Name
Dirithromycin Disk diffusion (KB) [Susc]
Consumer Name Alpha Get Info
Susceptibility to Dirithromycin

Part Model Get Info

  • Component
    Dirithromycin
    LP17270-7
    • Analyte
      Dirithromycin
      LP17270-7
      • Component Numerator
        Dirithromycin
        LP17270-7
        • Component Numerator Core
          Dirithromycin
          LP17270-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Susc
    LP6870-2
  • Time
    Pt
    LP6960-1
  • System
    Isolate
    LP7370-2
    • System Core
      Isolate
      LP7370-2
    • Super System
      NULL
       
  • Scale
    OrdQn
    LP7752-1
  • Method
    Agar diffusion
    LP6105-3

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.13
Last Updated
Version 2.19 (MIN)
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
50546-1Bacterial susceptibility panel by Disk diffusion (KB)

Member of these Groups Get Info

LOINC GroupGroup Name
LG41264-9DirithromycinSusc|Isolate

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Dirithromycin:Citlivost (mikroorganismy):Časový bod:Izolát:Ordinální nebo kvantitativní:Difúzní stanovení citlivosti na disku
de-DEGerman (Germany)Dirithromycin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Agardiffusionstest
el-GRGreek (Greece)Διριθρομυκίνη:Susc:Pt:Απομονωμένο στέλεχος:OrdQn:Διάχυση με άγαρ
Synonyms: ABXBACT OrdQn Pt Susc Απομονωμένο στέλεχος Διάχυση με άγαρ Διριθρομυκίνη
es-ARSpanish (Argentina)diritromicina:susceptibilidad:punto en el tiempo:cepa clínica:ordinal o cuantitativo:difusión en agar
es-ESSpanish (Spain)Diritromicina:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Difusión en disco; Kirby Bauer
es-MXSpanish (Mexico)Diritromicina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Difusión de disco (KB)
fr-CAFrench (Canada)Dirithromycine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Diffusion sur plaques
fr-FRFrench (France)Dirithromycine:Sensibilité:Ponctuel:Isolat:Alphanumérique:Diffusion gel Agar
fr-BEFrench (Belgium)Dirithromycine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Diffusion sur plaques
Synonyms: Diffusion en agar, précipitation en agar
it-ITItalian (Italy)Diritromicina:Susc:Pt:Isolato:OrdQn:Agar diffusione
Synonyms: Disco diffusione (KB) Kirby-Bauer Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
ko-KRKorean (Korea, Republic Of)디리스로마이신:감수성:검사시점:분리주:정량 or 순위척도:우무확산
nl-NLDutch (Netherlands)diritromycine:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:agardiffusie
pt-BRPortuguese (Brazil)Diritromicina:Susc:Pt:Isolado:OrdQn:Difusão em agar (disco)
Synonyms: DynAcac; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; KB; Kirby-bauer; Disk diffusion; ANTIBIOTIC SUSCEPTIBILITIES
tr-TRTurkish (Turkey)Diritromisin:Duyr:Zmlı:İzolat:SrlKant:Agar difüzyon
zh-CNChinese (China)地红霉素:抗生素敏感性:时间点:分离株:定量型或序数型:琼脂扩散法
Synonyms: KB 法;Kirby-bauer 法;平皿扩散;平皿扩散法;琼脂平皿扩散;琼脂平皿扩散法;琼脂扩散;琼脂板扩散;琼脂板扩散法 分离物;分离菌;分离菌株;隔离种群 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=35793-9