40452-5
Sialate/Creatinine [Ratio] in Urine
Active
Part Descriptions
LP15864-9 Sialate
Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone. It is also the name for the most common member of this group, N-acetylneuraminic acid (Neu5Ac or NANA). Sialic acids are found widely distributed in animal tissues and to a lesser extent in other species ranging from plants and fungi to yeasts and bacteria, mostly in glycoproteins and gangliosides. The amino group generally bears either an acetyl or glycolyl group but other modifications have been described. The hydroxyl substituents may vary considerably: acetyl, lactyl, methyl, sulfate, and phosphate groups have been found.
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Source: Wikipedia
, Wikipedia
LP15864-9 Sialate
Elevated sialic acid is a marker for a group of disorders known as sialic acid storage diseases, which are caused by a defect in the sialic acid transporter at the lysosomal membrane. The infantile form is characterized by hypotonia, cerebellar ataxia, and severe cognitive delay. The adult form is called Salla disease and is associated with slowly progressive neurodegeneration. Both forms are caused by mutations in the SLC17A5 gene, located on chromosome 6q13, which encodes a protein with two functions, one of which is as a lysosomal sialic acid transporter. [OMIM: 604369]
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Creatinine
Fully-Specified Name
- Component
- Sialate/Creatinine
- Property
- Ratio
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Sialate/Creatinine [Ratio] in Urine
- Short Name
- Sialate/Creat Ur-Rto
- Display Name
- Sialate/Creatinine (U) [Ratio]
- Consumer Name Alpha Get Info
- Sialate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Σιαλικό οξύ/Κρεατινίνη: Synonyms: Ratio Κρεατινίνη Σιαλικό οξύ |
es-ES | Spanish (Spain) | Sialato/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Sialato / Creatinina: |
et-EE | Estonian (Estonia) | Sialaat/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
fr-CA | French (Canada) | Sialate/Créatinine: |
fr-FR | French (France) | Sialate/créatinine: |
fr-BE | French (Belgium) | Sialate/Créatinine: |
it-IT | Italian (Italy) | Acido sialico/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) |
ko-KR | Korean (Korea, Republic Of) | 시알산염/크레아티닌: |
nl-NL | Dutch (Netherlands) | sialaat/creatinine: Synonyms: kreatinine |
pt-BR | Portuguese (Brazil) | Sialato/Creatinina: Synonyms: N-Acetylneuraminic Acid; |
ru-RU | Russian (Russian Federation) | Сиалат/Креатинин: Synonyms: Количественный Коэффициент; |
tr-TR | Turkish (Turkey) | Siyalat/Kreatinin: |
zh-CN | Chinese (China) | 唾液酸/肌酐: Synonyms: CR; |
Example Units
Unit | Source |
---|---|
nmol/mg{creat} | Example UCUM Units |
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