43133-8
Allopurinol and Oxipurinol panel [Mass/volume] - Serum or Plasma
Active
9736-0 Allopurinol [Mass/volume] in Serum or Plasma
Part Descriptions
LP17988-4 Allopurinol
A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.
Source: National Library of Medicine, MeSH 2006
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Allopurinol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Allopurinol SerPl-mCnc
- Display Name
- Allopurinol [Mass/Vol]
- Consumer Name Alpha Get Info
- Allopurinol, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0i
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 16023
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 43133-8 | Allopurinol and Oxipurinol panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG42263-0 | Allopurinol| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Allopurinol: |
| es-MX | Spanish (Mexico) | Alopurinol: |
| es-ES | Spanish (Spain) | Alopurinol: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | alopurinol: |
| et-EE | Estonian (Estonia) | Allopurinool: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Allopurinol: |
| fr-FR | French (France) | Allopurinol: |
| fr-CA | French (Canada) | Allopurinol: |
| it-IT | Italian (Italy) | Allopurinolo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 알로퓨리놀: |
| nl-NL | Dutch (Netherlands) | allopurinol: |
| pt-BR | Portuguese (Brazil) | Alopurinol: Synonyms: Lopurin; |
| ru-RU | Russian (Russian Federation) | Аллопуринол: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Allopurinol: |
| zh-CN | Chinese (China) | 别嘌呤醇: Synonyms: C5H4N4O 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
13908-9 Oxipurinol [Mass/volume] in Serum or Plasma
Part Descriptions
LP18483-5 Oxipurinol
Oxypurinol is an inhibitor of xanthine oxidase. It is an active metabolite of allopurinol and it is cleared renally. In cases of renal disease, this metabolite will accumulate to toxic levels.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Oxypurinol
LP18483-5 Oxipurinol
Oxipurinol [alloxanthine, Oxyprim, oxypurinol] is the active metabolite of the only commercially available xanthine oxidase inhibitor, allopurinol. Oxipurinol is also a xanthine oxidase inhibitor. Oxipurinol is currently being developed by Cardiome Pharma. It is waiting for approval in the US for the treatment of allopurinol-intolerant hyperuricaemia (gout) and is in phase III trials for the treatment of congestive heart failure. Allopurinol is indicated for the treatment of symptomatic hyperuricaemia, or gout. Approximately 3-5% of patients receiving allopurinol develop intolerance to the drug. Oxipurinol was originally developed by Burroughs Wellcome (later GlaxoSmithKline), and has been available on a compassionate-use basis since 1967 for use in allopurinol-intolerant patients. The licensee company ILEX Oncology has stated that oxipurinol does not have patent protection. Oxipurinol's potential for treatment of congestive heart failure is based on the possibility that xanthine oxidase inhibitors may improve myocardial work efficiency by sensitising cardiac muscle cells to calcium ions, which are a key determinant of cardiac muscle function. This results in more efficient contraction of cardiac muscle cells, without the same increase in oxygen demand. At the second annual BioPartnering North America conference (BPN-2004) [February 2004, Vancouver, Canada], Cardiome Pharma stated that it was seeking a commercialisation partner to market and distribute oxipurinol in the US for the treatment of allopurinol-intolerant hyperuricaemia. [Drugs R D. 2004;5(3):171-5.]
Source: NCBI PubMed, PMID:15139781
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Oxipurinol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Oxipurinol SerPl-mCnc
- Display Name
- Oxipurinol [Mass/Vol]
- Consumer Name Alpha Get Info
- Oxipurinol, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 16015
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 43133-8 | Allopurinol and Oxipurinol panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG1986-1 | Oxipurinol| |
| LG46197-6 | Oxipurinol| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-AR | Spanish (Argentina) | oxipurinol: |
| es-ES | Spanish (Spain) | Oxipurinol: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Oxipurinol: |
| et-EE | Estonian (Estonia) | Oksipurinool: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Oxipurinol: |
| fr-BE | French (Belgium) | Oxipurinol: |
| fr-FR | French (France) | Oxipurinol: |
| it-IT | Italian (Italy) | Ossipurinolo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | Oxipurinol: |
| nl-NL | Dutch (Netherlands) | oxipurinol: |
| pt-BR | Portuguese (Brazil) | Oxipurinol: Synonyms: Allopurinol metAcolite; |
| ru-RU | Russian (Russian Federation) | Оксипуринол: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Oksipürinol: |
| zh-CN | Chinese (China) | 奥昔嘌醇: Synonyms: 别嘌二醇; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |