43247-6

Catecholamines/Creatinine [Mass Ratio] in 24 hour Urine

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Part Descriptions

LP15090-1   Catecholamines
Catecholamines are chemical compounds derived from the amino acid tyrosine. Some of them are biogenic amines. Catecholamines are water soluble and are 50% bound to plasma proteins, so they circulate in the bloodstream. The most abundant catecholamines are epinephrine (adrenaline), norepinephrine (noradrenaline) and dopamine. They are produced mainly from the adrenal medulla and the postganglionic fibers of the sympathetic nervous system. Epinephrine acts as a neurotransmitter in the central nervous system and as a hormone in the blood circulation. Norepinephrine is primarily a neurotransmitter of the peripheral sympathetic nervous system but is also present in the blood (mostly through spillover from the synapses of the sympathetic system). High catecholamine levels in blood are associated with stress, which can be induced from psychological reactions or environmental stressors such as elevated sound levels or intense light. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Catecholamines (Wikipedia)

LP15090-1   Catecholamines
A general class of ortho-dihydroxyphenylalkylamines derived from tyrosine. Source: National Library of Medicine, MeSH 2006

LP15090-1   Catecholamines
Catecholamines are synthesized in the adrenal medulla, brain, and sympathetic nervous system. Urine catecholamine fractionation is often performed to diagnose catecholamine-secreting neoplasms, of which more than 90% are adrenal pheochromocytomas. Increases in epinephrine and/or norepinephrine are seen with adrenal pheochromocytomas. Normally, catecholamines are taken up by storage particles, excreted into urine, or converted to metabolites(metanephrine, normetanephrine, methoxyhydroxyphenylglycol, vanillylmandelic acid). Information from Jacobs and DeMott Laboratory Test Handbook, 5th edition, DS Jacobs, WR DeMott and DK Oxley, 2001. 2007 08 06. Source: Regenstrief Institute

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

Catecholamines/Creatinine

Property

MRto

Time

24H

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Catechols/Creat 24h Ur

Display Name

Catecholamines/Creatinine (24H U) [Mass ratio]

Consumer Name Alpha Get Info

Catecholamines/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.17

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

10469

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 1 day
• 24 hours
• 24HR
• Cate
• Catec
• Catech
• Catechol
• Catecholamine
• Catecholamines.total
• Catechols
• Chemistry
• CR
• Crea
• Creat
• Epinephrine+norepinephrine+dopamine
• Mass concentration ratio
• Mass ratio
• MCRto
• QNT
• Quan
• Quant
• Quantitative
• UA
• UCr
• UR
• Urn

Example Units

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