Version 2.78

Part Description

LP28423-9   West Nile virus
The West Nile Virus (WNV) is an arbovirus that was first identified in the West Nile District of Uganda in 1937. In the fall of 1999, the National Veterinary Services Laboratory (NVLS) isolated WNV in a dead crow in New York City.(http://www.who.int/mediacentre/factsheets/fs354/en/) Over the following ten years, WNV spread throughout the United States, Canada, Mexico and the Carribbean. WNV is usually transmitted through the bite of the Culex mosquito, but can also be spread in blood transfusions, organ transplants, breast milk, intrauterine exposure and laboratory-acquired infections. Birds are the preferred host of WNV, and the American robin is an important amplifier host since it develops enough virus in its serum to infect feeding mosquitoes. Though most infections with WNV are subclinical for humans, between 2005 and 2009 there were 12,975 people infected with WNV, of which 35% had severe cases of neuroinvasive disease and 496 people died. For individuals who are 70 years of age or older, infection with WNV has a 15-29% fatality rate. For infants and immunocompromised patients infected with WNV, the fatality rate is even higher. Diagnosis of WNV is based on clinical symptoms and antibody titers. The IgM antibody-capture enzyme-linked immunosorbent assay (MAC-ELISA) is the key method used to diagnosis WNV in clinical settings. Antibody titers to WNV NS5 are detectable long-term in vivo and can be used to distinguish past infection with WNV from current infection. RNA is usually undetectable in serum after 13.2 days, but on rare occasions, has been found in serum beyond 40 days. Treatment of infection with WNV is mostly supportive. There are no FDA-approved drugs or vaccines available. PMID: 12089283 PMID: 23034323 Source: Regenstrief LOINC

Fully-Specified Name

Component
West Nile virus Ab.IgM
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method
IA

Additional Names

Short Name
WNV IgM Titr Ser IA
Display Name
West Nile virus IgM IA (S) [Titer]
Consumer Name Alpha Get Info
West Nile virus IgM antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.75
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32768-0 West Nile virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) West-Nil-Virus Ak.IgM:Titer:Zeitpunkt:Serum:Semiquantitativ:Immunoassay
es-ES Spanish (Spain) Virus Nilo Occidental IgM:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:IA
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Ab.IgM del virus del Nilo Occidental:Título:Punto temporal:Suero:Cuantitativo:Inmunoensayo
fr-CA French (Canada) Virus du Nil occidental, IgM:Titre:Temps ponctuel:Sérum:SemiQn:IA
fr-FR French (France) West Nile virus Ac IgM:Titre:Ponctuel:Sérum:Semi-Quantitatif:Immunoanalyse
it-IT Italian (Italy) Nilo occidentale, virus Ab.IgM:Titr:Pt:Siero:SemiQn:IA
Synonyms: Anticorpi IgM anticorpo Immunoassay Microbiologia Punto nel tempo (episodio) Siero Titolo Virus del Nilo occidentale
nl-NL Dutch (Netherlands) West-Nijlvirus As.IgM:titer:moment:serum:semikwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
pl-PL Polish (Poland) Wirus gorączki zachodniego Nilu Ab.IgM:miano:punkt w czasie:surowica:półilościowy:metoda immunologiczna
Synonyms: IgM Przeciwciała do wirusa gorączki zachodniego Nilu Przeciwciała IgM do wirusa gorączki zachodniego Nilu
pt-BR Portuguese (Brazil) Vírus do Nilo Ocidental Ac.IgM:Título:Pt:Soro:Qn:Imunoensaio
Synonyms: ; WNV; Immune globulin M; Immunoglobulin M; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN Chinese (China) 西尼罗河病毒 抗体.IgM:滴定度:时间点:血清:半定量型:免疫测定法
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 WNV Ab WNV Ab.IgM WNV 抗体 WNV 抗体.IgM WNV;西尼罗河热;西尼罗河热病毒 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 M 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 西尼罗河热病毒 Ab 西尼罗河热病毒 Ab.IgM 西尼罗河热病毒抗体 西尼罗河热病毒抗体.IgM 西尼罗河病毒 Ab 西尼罗河病毒 Ab.IgM 西尼罗河病毒 IgM

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43343-3