44407-5
Somatotropin/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP14695-8 Somatotropin
Somatotropin (growth hormone) is essential for normal growth and development in children and helps regulate metabolism in both children and adults. The pituitary gland produces and releases GH into the blood in pulses throughout the day.
Because growth hormone is released in pulses, a single measurement of the blood level is not normally clinically useful. Therefore, testing for the suppression or stimulation of growth hormone release from the pituitary is usually done.
GH stimulation (challenge) tests help to diagnose GH deficiency and hypopituitarism. For a stimulation test, a sample of blood is drawn after 10-12 hours of fasting. Then, under close medical supervision, a person is given an intravenous solution of a substance that normally stimulates the release of GH from the pituitary. Blood samples are then drawn at timed intervals and GH levels are tested in each to see if the pituitary gland was stimulated to produce the expected levels of GH. The most commonly used challenge is arginine, but others include clonidine and glucagon. Since exercise normally causes an increase in GH, vigorous exercise may also be used as the stimulant for GH release.
GH suppression tests help to diagnose GH excess. For a suppression test, a sample of blood is drawn after 10-12 hours of fasting. A person is then given a standard glucose solution (usually 100 grams of glucose) to drink. Blood samples are drawn at timed intervals and tested for GH to see if the pituitary gland is sufficiently suppressed by the dose of glucose.
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Source: Lab Tests Online®
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Somatotropin/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- GH/Creat Ur
- Display Name
- Somatotropin/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- Somatotropin/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.42
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Somatotropina/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Somatotropina / Creatinina: |
| et-EE | Estonian (Estonia) | Kasvuhormoon/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Somatotropiin Uriin |
| fr-CA | French (Canada) | Hormone de croissance/Créatinine: Synonyms: GH |
| fr-FR | French (France) | Somatotropine/créatinine: |
| fr-BE | French (Belgium) | Hormone de croissance/Créatinine: Synonyms: GH, hGH Rapport de masse |
| it-IT | Italian (Italy) | Somatotropina/Creatinina: Synonyms: Chimica GH Punto nel tempo (episodio) Rapporto di Massa |
| nl-NL | Dutch (Netherlands) | somatotropine/creatinine: Synonyms: kreatinine |
| pt-BR | Portuguese (Brazil) | Somatotrofina/Creatinina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Соматотропин/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
| tr-TR | Turkish (Turkey) | Somatotropin/Kreatinin: |
| zh-CN | Chinese (China) | 生长激素/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| ng/g{creat} | Example UCUM Units |
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