44702-9
Complement C1q Ab [Units/volume] in Serum
Active
Part Descriptions
LP16352-4 Complement C1q
A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY.
Source: National Library of Medicine, MeSH 2006
LP16352-4 Complement C1q
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement (C1) is composed of 3 subunits: C1q, C1r, and C1s. Complement C1q initiates the complement pathway by binding to immunoglobulins. Absent or decreased levels of Complement C1q are seen in patients with acquired angioedema, systemic lupus erythematosus (SLE), polymyositis, and other immune complex diseases. Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Complement C1q Ab
- Property
- ACnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Complement C1q Ab [Units/volume] in Serum
- Short Name
- C1q Ab Ser-aCnc
- Display Name
- Complement C1q Ab Qn (S)
- Consumer Name Alpha Get Info
- Complement C1q antibody, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 14384
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Anti-C1q AK |
de-DE | German (Germany) | Komplement C1q Ak: |
el-GR | Greek (Greece) | Συμπλήρωμα C1q Αντίσωμα: Synonyms: ACnc Συμπλήρωμα C1q |
es-ES | Spanish (Spain) | Complemento C1q Anticuerpos: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Complemento C1q Ab: |
et-EE | Estonian (Estonia) | Komplemendi komponent C1q antikehad: Synonyms: Juhuslik Kvantitatiivne Seerum |
fr-CA | French (Canada) | Complément C1q, Ac: |
fr-FR | French (France) | Complément C1q anticorps: |
fr-BE | French (Belgium) | Complément C1q Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Complemento C1q Ab: Synonyms: anticorpo Concentrazione Arbitraria Ematologia (coagulazione) conta differenziale Punto nel tempo (episodio) Siero |
nl-NL | Dutch (Netherlands) | complement C1q As: Synonyms: antistof; |
pt-BR | Portuguese (Brazil) | Complemento C1q Ac: Synonyms: Complement c1q binding; |
ru-RU | Russian (Russian Federation) | Комплемент C1q Ат: Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Kompleman C1q Ab: |
zh-CN | Chinese (China) | 补体 C1q 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
[arb'U]/mL | Example UCUM Units |
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