44719-3
Methylmalonate/Homocysteine [Mass Ratio] in Serum or Plasma
Active
Part Descriptions
LP15735-1 Methylmalonate
Methylmalonate (methylmalonic acid) is measured as a second-tier assay when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screening. Methylmalonic acidemia (MMA) and propionic acidemia (PA) are defects of propionate metabolism caused by deficiencies in methylmalonyl-CoA mutase and propionyl-CoA carboxylase, respectively. The clinical phenotype of both conditions includes vomiting, hypotonia, lethargy, apnea, hypothermia, and coma. The biochemical phenotype for MMA includes elevated methylmalonic acid, propionyl carnitine and methylcitric acid, while patients with PA have elevated propionyl carnitine and methylcitric acid with normal methylmalonic acid concentrations as the enzymatic defect is upstream of methylmalonic-CoA mutase.
Source: Regenstrief LOINC
LP70332-9 Homocysteine
Homocysteine, an amino acid with the formula HSCH2CH2CH(NH2)CO2H, is a homologue of the amino acid cysteine, differing from it only by an additional methylene (-CH2-) group. It is biosynthesized from methionine by the removal of its terminal Cε methyl group. Homocysteine can be recycled into methionine or converted into cysteine with B-vitamins.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Homocystine
Fully-Specified Name
- Component
- Methylmalonate/Homocysteine
- Property
- MRto
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Methylmalonate/Homocysteine [Mass Ratio] in Serum or Plasma
- Short Name
- Methylmalonate/Homocysteine SerPl
- Display Name
- Methylmalonate/Homocysteine [Mass ratio]
- Consumer Name Alpha Get Info
- Methylmalonate/Homocysteine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.42 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Methylmalonat/Homocystein: Synonyms: Methylmalonsäure |
el-GR | Greek (Greece) | Μεθύλομαλονικό οξύ/Ομοκυστεΐνη: Synonyms: MRto Μεθύλομαλονικό οξύ Ομοκυστεΐνη |
es-ES | Spanish (Spain) | Metilmalonato/Homocisteína: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Malonato de metilo / homocisteína: |
et-EE | Estonian (Estonia) | Metüülmalonaat/homotsüsteiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-FR | French (France) | Méthylmalonate/homocystéine: |
it-IT | Italian (Italy) | Metilmalonato/Omocisteina: Synonyms: Chimica Plasma Punto nel tempo (episodio) Rapporto di Massa Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | methylmalonaat/homocysteïne: |
pt-BR | Portuguese (Brazil) | Metilmalonato/Homocísteina: Synonyms: MMA; |
ru-RU | Russian (Russian Federation) | Метилмалонат/Гомоцистеин: Synonyms: Количественный Масс отношение Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Metilmalonat/Homosistein: |
zh-CN | Chinese (China) | 甲基丙二酸/同型半胱氨酸: Synonyms: HCY; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=44719-3
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://