4478-4
Complement C1q [Mass/volume] in Serum or Plasma
Active
Part Descriptions
LP16352-4 Complement C1q
A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY.
Source: National Library of Medicine, MeSH 2006
LP16352-4 Complement C1q
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement (C1) is composed of 3 subunits: C1q, C1r, and C1s. Complement C1q initiates the complement pathway by binding to immunoglobulins. Absent or decreased levels of Complement C1q are seen in patients with acquired angioedema, systemic lupus erythematosus (SLE), polymyositis, and other immune complex diseases. Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Complement C1q
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Complement C1q [Mass/volume] in Serum or Plasma
- Short Name
- C1q SerPl-mCnc
- Display Name
- Complement C1q [Mass/Vol]
- Consumer Name Alpha Get Info
- Complement C1q, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 3194
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Komplement C1q: |
el-GR | Greek (Greece) | Συμπλήρωμα C1q: Synonyms: MCnc Συμπλήρωμα C1q |
es-AR | Spanish (Argentina) | complemento C1Q: |
es-ES | Spanish (Spain) | Complemento C1q: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Complemento C1q: |
et-EE | Estonian (Estonia) | Komplemendi komponent C1q: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Complément C1q: |
fr-FR | French (France) | Complément C1q: |
fr-BE | French (Belgium) | Complément C1q: |
it-IT | Italian (Italy) | Complemento C1q: Synonyms: Concentrazione di Massa Ematologia (coagulazione) conta differenziale Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 도움체 C1q: |
nl-NL | Dutch (Netherlands) | complement C1q: |
pt-BR | Portuguese (Brazil) | Complemento C1q: Synonyms: Complement c1q binding; |
ru-RU | Russian (Russian Federation) | Комплемент C1q: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Kompleman C1q: |
zh-CN | Chinese (China) | 补体 C1q: Synonyms: 可用数量表示的; |
Example Units
Unit | Source |
---|---|
mcg/mL | REGENSTRIEF |
mg/dL | REGENSTRIEF |
ug/mL | Example UCUM Units |
ug/mL | eCHN |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=4478-4
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