Version 2.80

Term Description

Pyridoxal phosphate is a derivative of Vitamin B6 and is used by enzymes in all organisms. The majority of enzymes which depend on pyridoxal phosphate are associated with pathways involving amino acids, such as amino group transfer, decarboxylation and other important biochemical processes. [PMCID:1326353]
When measuring AST and/or ALT without pyridoxal-5-phosphate (P-5-P), the rate of the decrease of NADH is directly proportional to the AST/ALT (respectively)-activity in the specimen. Testing for AST and/or ALT with the addition of P-5-P stabilizes the transaminases in the specimen and avoids falsely low values in specimens of patients suffering from either myocardial infarction or liver disease, who have an insufficient amount of P-5-P in their blood.
Source: Regenstrief LOINC

Part Description

LP15426-7   Aspartate aminotransferase
Aspartate aminotransferase (AST) is an enzyme that is released by injured muscle cells and liver cell and is predominately found in the liver and heart. AST levels in the blood are most often used to monitor liver damage. AST is typically tested in conjunction with alanine aminotransferase (ALT) when a liver panel is ordered. High levels of AST in the bloodstream could indicate hepatitis, drug damage to the liver, cirrhosis, alcoholism, or other liver disorders. [Lab Tests Online:ast/tab/test] Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Aspartate Aminotransferase (AST)

Fully-Specified Name

Component
Aspartate aminotransferase
Property
CCnc
Time
Stdy^max
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Aspartate aminotransferase [Enzymatic activity/volume] (Maximum value during study) in Serum or Plasma
Short Name
AST (Study max) SerPl-cCnc
Display Name
AST (Stdy maximum) [Catalytic activity/Vol]
Consumer Name Alpha Get Info
Aspartate Aminotransferase (AST; SGOT), Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.68 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Aspartat-Aminotransferase:Katalytische Konzentration:Untersuchung^Maximum:Serum oder Plasma:Quantitativ:
Synonyms: AST; GOT; ASAT
el-GR Greek (Greece) Ασπαρτική αμινοτρανσφεράση:CCnc:Stdy^μέγ:Ορός/Πλάσμα:Qn:
Synonyms: CCnc Ασπαρτική αμινοτρανσφεράση Ασπαρτικό
es-ES Spanish (Spain) Aspartato amino transferasa:Concentración Catalítica:Estudio^Valor maximo durante un intervalo:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Aspartato aminotransferasa:Concentración catalítica:Estudio^max:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Aspartaadi aminotransferaas:CCnc:Stdy^max:S/P:Qn:
Synonyms: Kvantitatiivne Plasma Seerum Seerum või plasma Uuring
fr-CA French (Canada) Aspartate aminotransférase:Concentration catalytique:Étude^maximun:Sérum/Plasma:Quantitatif:
fr-FR French (France) Aspartate aminotransférase:Catalytique/Volume:Étude max:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Aspartate aminotransférase, Transaminase GO:Concentration catalytique:Étude^maximum:Sérum/Plasma:Quantitatif:
Synonyms: SGOT,ASAT, TGO, AST
it-IT Italian (Italy) Aspartato aminotransferasi:CCnC:Studio^max:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione Catalitica massimo Plasma Siero Siero o Plasma
nl-NL Dutch (Netherlands) aspartaataminotransferase:enzymatische activiteit/volume:onderzoek^maximum:serum of plasma:kwantitatief:
Synonyms: ASAT
pt-BR Portuguese (Brazil) Aspartato amino transferase:CCnc:Stdy^max:Sor/Plas:Qn:
Synonyms: ; AST; Aspartate amino transferase; Glutamic oxaloacetic transaminase; Aspartate transaminase; SGOT; Asp; Aspartic acid; Catalytic Concentration; Sutdies; Studies; Study; Maximum; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU Russian (Russian Federation) Аспартат аминотрансфераза:КаталКонц:Исслед^максимум:Сыв/Плаз:Колич:
Synonyms: Аспартатаминотрансфераза;АСТ Исследование Каталитическая концентрация Количественный Плазма Сыворотка Сыворотка или Плазма
tr-TR Turkish (Turkey) Aspartat aminotransferaz:KtlKons:Çlşm^maks:Ser/Plaz:Kant:
zh-CN Chinese (China) 天冬氨酸氨基转移酶:催化浓度:检查过程持续时间^最大值:血清/血浆:定量型:
Synonyms: Asp;天冬氨酸;门冬氨酸 AST;SGOT;天冬氨酸转氨酶;天门冬氨酸氨基转移酶;谷氨酸-草酰乙酸氨基转移酶;谷氨酸-草酰乙酸转氨酶;谷草;谷草转氨酶;门冬氨酸氨基转移酶;门冬氨酸转氨酶 催化浓度(单位体积);单位体积内酶的单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 最大;极大值 检查;检查持续时间;检查过程 血清或血浆

Example Units

Unit Source
U/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=44786-2