Version 2.77

Status Information

Status
DEPRECATED
Reason
Duplicate
Map-To Long Common Name Mapping Guidance
44740-9 Ganglioside GD1a Ab [Presence] in Serum

Part Descriptions

LP14393-0   Ganglioside GD1a
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559 Source: Regenstrief LOINC, PMID: 2121455

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ganglioside GD1a Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Ord
Method

Additional Names

Short Name
Deprecated GD1a Gangl Ab Ser Ql
Display Name
Ganglioside GD1a Ab Ql (S)
Consumer Name Alpha Get Info
Ganglioside GD1a antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.36
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG12294-1 Ganglioside GD1a Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gangliosido GD1a Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Ord:
es-MX Spanish (Mexico) Gangliósido GD1a Ab:Concentración arbitraria:Punto temporal:Suero:Ordinal:
et-EE Estonian (Estonia) Gangliosiid GD1a antikehad:Acnc:Pt:S:Ord:
Synonyms: Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Ganglioside GD1a , Ac:Concentration arbitraire:Temps ponctuel:Sérum:Ordinal:
fr-BE French (Belgium) Ganglioside GD1a Ac:Concentration arbitraire:Temps ponctuel:Sérum:Ordinal:
Synonyms: Anticorps
it-IT Italian (Italy) Ganglioside GD1a Ab:ACnc:Pt:Siero:Ord:
Synonyms: anticorpo Concentrazione Arbitraria Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) ganglioside GD1a As:eenheid/volume:moment:serum:ordinaal:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Gangliosideo GD1b Ac:ACnc:Pt:Soro:Ord:
Synonyms: ; GD1a Gangl; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Ганглиозид GD1a Ат:ПроизвКонц:ТчкВрм:Сыв:Пор:
Synonyms: Антитело Порядковый Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Gangliozid GD1a Ab:SçKons:Zmlı:Ser:Srl:
Synonyms: Ak
zh-CN Chinese (China) 神经节苷脂 GD1a 抗体:任意型浓度:时间点:血清:序数型:
Synonyms: Ab;自身抗体 GD1a;神经节糖苷 GD1a 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 时刻;随机;随意;瞬间 神经节糖苷 神经节苷脂 GD1a Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=45202-9