Version 2.77

Part Descriptions

LP36683-8   ABO & Rh group
In 1900, Landsteiner observed that the red cells of some individuals were agglutinated by the serum of others and his detailed report a year later heralded the discovery of the first human blood groups. His limited experiments on laboratory colleagues demonstrated three distinct groups; his pupils Von Decastello and Sturli discovered a fourth group in 1902. It was 25 years before these groups were shown to be inherited as Mendelian characters by means of three allelomorphic genes A, B and O and were, in fact, entities of one blood group system. For most of medicine this was considered a meaningless curiosity, but for those involved with the early development of transfusions it was quickly noted that transfusion of blood only of the same group could mean the difference between a successful outcome or a fatality. While various nomenclatures have been used to describe these factors, it was internationally decided in the mid-1940's that the characteristics would be individually identified as A, B, AB and O and the blood group system know as ABO. Since that time there have been billions of tests preformed and almost as many publications describing various aspects and associations of this blood group systems or its allelic products. The genes controlling the ABO system are located on the long arm of chromosome 9 and encode for either an a (1-3) N-acetylgalactosaminyltransferase (for A) or a (1,3) galactosyltransferase (for B). These transferases incorporate immunodominant sugars (GalNAc for A; Gal for B) on to one of four different types of oligosaccharide chains (type 2 is predominant on red cells, type 1 is found in secretions, plasma and some tissue) carried on glycosphingolipid or glycoprotein molecules. The placement of the A and B antigens is dependent upon the existence of a substrate produced by the Hh blood group system (ISBT # 018). Some individuals have weakened or variant expression of A and/or B which can be attributed to inheritance of variant forms of transferases. Those individuals that have neither transferases, inheritors of two amorph genes, are group O. To date, 14 A alleles, 14 B alleles and 8 O alleles have been identified at the molecular level and more remain to be found. The ABO antigens, as stated above are not restricted to the red blood cell membrane but can be found in saliva and all body fluids except spinal fluid if the individual has inherited a secretor gene. The antigens are also found on most epithelial and endothelial cells. It also appears on lymphocytes and platelets as it is adsorbed from the plasma. Alterations of ABH expression have been found in various forms of cancer. Furthermore, antigens of the ABO system may play a role in resistance to bacteria or viruses. Source: Serum, Cells and Rare Fluid Exchange, ABO & Rh

LP412149-9   post transfusion reaction BldBk
Investigation of a putative transfusion reaction involves repeat blood typing on the patient's pre-transfusion sample, a sample from the transfused unit, as well as a post-transfusion sample from the patient (where a mixed field pattern suggests that incompatible donor cells were given). Source: Regenstrief LOINC

Fully-Specified Name

Component
ABO & Rh group^post transfusion reaction
Property
Type
Time
Pt
System
Bld^BPU
Scale
Nom
Method

Additional Names

Short Name
ABO + Rh p transf rx Bld BPU
Display Name
ABO and Rh group post transfusion reaction (Bld BPU)
Consumer Name Alpha Get Info
ABO and Rh group after Transfusion Reaction, Blood Product Unit

Preferred Answer List: LL2972-9

Source: Canada Health Infoway
Answer Code Score Answer ID
O PosCopyright http://snomed.info/sct ID:278147001 Blood group O Rh(D) positive (finding) LA21321-7
O NegCopyright http://snomed.info/sct ID:278148006 Blood group O Rh(D) negative (finding) LA21322-5
B PosCopyright http://snomed.info/sct ID:278150003 Blood group B Rh(D) positive (finding) LA21327-4
B NegCopyright http://snomed.info/sct ID:278153001 Blood group B Rh(D) negative (finding) LA21328-2
AB PosCopyright http://snomed.info/sct ID:278151004 Blood group AB Rh(D) positive (finding) LA21323-3
AB NegCopyright http://snomed.info/sct ID:278154007 Blood group AB Rh(D) negative (finding) LA21324-1
A PosCopyright http://snomed.info/sct ID:278149003 Blood group A Rh(D) positive (finding) LA21325-8
A NegCopyright http://snomed.info/sct ID:278152006 Blood group A Rh(D) negative (finding) LA21326-6

Basic Attributes

Class
BLDBK
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
19462

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Grupo ABO y Rh^Reacción pos-transfusional:Tipo:Punto temporal:Sangre^Unidad de hemoderivado:Nom:
Synonyms: Grupos sanguíneos AB0 y Rh
es-MX Spanish (Mexico) ABO y grupo Rh ^ reacción postransfusional:Tipo:Punto temporal:Sangre ^ Unidad de hemoderivado:Nominal:
fr-CA French (Canada) Groupe ABO & Rh^Réaction post-transfusionnelle:Type:Temps ponctuel:Sang^Unité de produit sanguin:Nominal:
fr-FR French (France) ABO et RHD groupage après réaction transfusionnelle:Type:Ponctuel:Poche de sang:Résultat nominal:
it-IT Italian (Italy) ABO & Rh, gruppo^reazione post trasfusionale:Tipo:Pt:Sangue^Unità prodotto sangue:Nom:
Synonyms: Banca del sangue dopo trasfusione Gruppo ABO & Rh Gruppo Rh Punto nel tempo (episodio) Reazione trasfusionale Sangue Unità di prodotto sangue
nl-NL Dutch (Netherlands) AB0 & Rh-bloedgroep^na transfusiereactie:type:moment:bloed^bloedproducteenheid:nominaal:
pt-BR Portuguese (Brazil) Grupo ABO+Rh^após reação transfusional:Tipo:Pt:Sg^bolsa de sangue:Nom:
Synonyms: ; Transf React; Rh typing; D typing; Rh phenotyping; D phenotyping; AcO+Rh Gp; ABO group and Rh type; p transf rx; Typ; Point in time; Random; Blood; WB; Whole blood; Blood product unit; Nominal; Rxn; Tx; PST; After; BLOOD BANK
ru-RU Russian (Russian Federation) ABO & Rh^Посттрансфузионная реакция:Тип:ТчкВрм:Кр^КПЕ:Ном:
Synonyms: Кровь Кровь препарат единица;Доза;Единица препарата крови Номинальный;Именной Реакция на трансфузию Точка во времени;Момент
tr-TR Turkish (Turkey) ABO ve Rh^snr transfüzyon reaksiyonu:Tip:Zmlı:Kan^KanÜrÜ:Snf:
Synonyms: Tür
zh-CN Chinese (China) ABO与Rh血型^在输血反应之后:类型:时间点:全血^血液制品单位:名义型:
Synonyms: ABO & Rh 型;ABO 与 Rh 型;ABO 血型 & Rh 类型;ABO 血型+Rh 类型;ABO 血型与Rh 类型;ABO+Rh血型;ABO与Rh血型;血库成分 - ABO与Rh血型 ABO血型与Rh血型;ABO与Rh BPU;血液制品单位(Blood product unit,BPU);血液制品单位(包装);血液包装单位;超系统 - 血液制品单位 D 分型;D 定型;D 表现型鉴定;Rh 分型;Rh 型;Rh 定型;Rh 表现型鉴定 React Rxn XXX刺激 - 在...之后 之后于... 之后于输血 之后于输血反应 全血^BPU 全血^血液制品单位 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 响应 在...以后 在后 型 时刻;随机;随意;瞬间 注入 灌输 血;血液 血库;血库检验;血库检验类;血库检验项目;血库检验项目类;血库类;血库试验;血库试验项目;血库试验项目类 血库成分 - 输血 血库成分 - 输血反应;输液反应 血液^BPU 输注 输液 输血法

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=46268-9