48143-2
LDL.oxidized Ab [Units/volume] in Serum
Active
Part Description
LP62198-4 LDL.oxidized
Once LDL accumulates in the subendothelial space, it tends to become modified or oxidized. This oxidized LDL plays several key roles in furthering the course of the inflammatory process. It is chemotactic to monocytes; oxidized LDL causes endothelial cells to secrete molecules that cause monocytes to penetrate between the endothelial cells and accumulate in the intima.
Oxidized LDL promotes death of endothelial cells by augmenting apoptosis. Also, through the activation of collagenases, ox-LDL contributes to a process which may lead to the rupture of the fibrous plaque. Oxidized LDL decreases the availability of endothelial nitric oxide (NO), which, in turn, increases the adhesion of monocytes to the endothelium. Moreover, NO is involved in paracrine signalling between the endothelium and the smooth muscle that maintains vascular tone; without it, the muscle will not relax, and the blood vessel remains constricted. Thus, oxidized LDL also contributes to the hypertension often seen with atherosclerosis.
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Source: Wikipedia
, Role of oxidized LDL
Fully-Specified Name
- Component
- LDL.oxidized Ab
- Property
- ACnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- LDL.oxidized Ab [Units/volume] in Serum
- Short Name
- LDL.oxidized Ab Ser-aCnc
- Display Name
- LDL.oxidized Ab Qn (S)
- Consumer Name Alpha Get Info
- LDL.oxidized antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9121
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG19294-4 | LDL.oxidized Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: LDL-oxidiert AK |
de-DE | German (Germany) | LDL.oxidiert Ak: |
el-GR | Greek (Greece) | LDL.οξειδωμένη Αντίσωμα: Synonyms: ACnc LDL.οξειδωμένη |
es-ES | Spanish (Spain) | LDL. oxidadas Anticuerpos: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Ab oxidado con LDL: |
fr-CA | French (Canada) | LDL.oxydées, Ac: |
fr-FR | French (France) | LDL oxydés anticorps: |
fr-BE | French (Belgium) | LDL.oxydées Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | LDL.ossidato Ab: Synonyms: anticorpo Concentrazione Arbitraria Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | LDL.geoxideerd As: Synonyms: antistof; |
pt-BR | Portuguese (Brazil) | LDL.oxidizado Ac: Synonyms: oxLDL; |
ru-RU | Russian (Russian Federation) | ЛПНП.окисленные Ат: Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | LDL.okside Ab: |
zh-CN | Chinese (China) | 低密度脂蛋白.氧化型 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
m[arb'U]/mL | Example UCUM Units |
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