Version 2.78

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus DNA
Property
NCnc
Time
Pt
System
Urine
Scale
Qn
Method
Probe.amp.tar

Additional Names

Short Name
CMV DNA # Ur NAA+probe
Display Name
CMV DNA NAA+probe (U) [#/Vol]
Consumer Name Alpha Get Info
Cytomegalovirus (CMV), Urine

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
3445

Member of these Groups Get Info

LOINC Group Group Name
LG34273-9 Cytomegalovirus DNA|NCnc|Sys:ANYGU
LG36512-8 Cytomegalovirus DNA|NCnc|Urine

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus DNA:Anzahl pro Volumen:Zeitpunkt:Urin:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
Synonyms: CMV
es-ES Spanish (Spain) Citomegalovirus ADN:Concentración de número:Punto temporal:Orina:Qn:Sonda con amplificación dirigida
Synonyms: Cuantitativo
es-MX Spanish (Mexico) ADN de citomegalovirus:Concentración numérica:Punto temporal:Orina:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Cytomégalovirus, ADN:Concentration numérique:Temps ponctuel:Urine:Quantitatif:Sonde avec amplification de la cible
fr-FR French (France) Cytomégalovirus ADN:Nombre/Volume:Ponctuel:Urine:Numérique:PCR amplification de cible
fr-BE French (Belgium) Cytomégalovirus ADN:Concentration numérique:Temps ponctuel:Urine:Quantitatif:Sonde avec amplification de la cible
Synonyms: CMV
it-IT Italian (Italy) Citomegalovirus DNA:NCnc:Pt:Urine:Qn:Sonda.amp.tar
Synonyms: Concentrazione Numerica Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Cytomegalovirus DNA:aantal/volume:moment:urine:kwantitatief:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Citomegalovírus DNA:NCnc:Pt:Urina:Qn:Sonda com limite de detecção da amplificação de alvo
Synonyms: Deoxyribonucleic acid; CMV; Cytomgal; Cytomegalo virus; #; Number concentration; Count/mass; Count; AcS; CT; Acsolute; Acsolutes; Cnt; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Microbiology; Viral load
ru-RU Russian (Russian Federation) Цитомегаловирус ДНК:КолОб:ТчкВрм:Моча:Колич:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Количественный Количество в объеме Проба с мишени усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus DNA:SayKons:Zmlı:İdrar:Kant:Prob.amf.hdf
zh-CN Chinese (China) 巨细胞病毒 DNA:计数型浓度:时间点:尿液:定量型:探针法.基因扩增.靶向
Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 单位体积内的数量或计数;数量型浓度(单位体积);数量或计数型浓度(计数/体积);数量或计数型浓度(单位体积);计数型浓度(单位体积) 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 数量型浓度 探针法.基因扩增.靶向 数量型浓度 探针法.扩增.靶向 数量或计数型浓度 探针法.扩增.靶向 时刻;随机;随意;瞬间 病毒负荷 病毒负荷量 病毒负载 病毒载量 病毒载量（Viral load） 经过扩增的 脱氧核糖核酸探针 计数型浓度 探针法.基因扩增.靶向 计数型浓度 探针法.扩增.靶向

Example Units

Unit Source
{copies}/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49347-8