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Part Description

LP15698-1   Sphingomyelin
Sphingomyelin (SPH) is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath that surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide. In humans SPH represents ~85% of all sphingolipids.

Sphingomyelin can accumulate in a rare hereditary disease called Niemann-Pick Disease, types A and B. It is a genetically-inherited disease caused by a deficiency in the enzyme Sphingomyelinase, which causes the accumulation of Sphingomyelin in spleen, liver, lungs, bone marrow, and the brain, causing irreversible neurological damage. Of the two types involving Sphingomyelinase, type A occurs in infants. It is characterized by jaundice, an enlarged liver, and profound brain damage. Children with this type rarely live beyond 18 months. Type B involves an enlarged liver and spleen, which usually occurs in the pre-teen years. The brain is not affected. Most patients present with <1% normal levels of the enzyme in comparison to normal levels.

An excess of spingomyelin in the red blood cell membrane (as in abetalipoproteinemia) causes excess lipid accumulation in the outer leaflet of the red blood cell plasma membrane. This results in abnormally shaped red cells called acanthocytes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
Sphingomyelin/Surfactant.total:MFr:Pt:Amnio fld:Qn:
Long Common Name
Sphingomyelin/Surfactant.total in Amniotic fluid
Short Name
Sphingomyelin MFr Amn
Display Name
Sphingomyelin/Total surfactant (Amn fld) [Mass fraction]
Consumer Name Alpha Get Info
Sphingomyelin/Surfactant.total, Amniotic fluid

Part Model Get Info

  • Component
    Sphingomyelin/Surfactant.total
    LP287134-3
    • Analyte
      Sphingomyelin/Surfactant.total
      LP287134-3
      • Component Numerator
        Sphingomyelin
        LP15698-1
        • Component Numerator Core
          Sphingomyelin
          LP15698-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Surfactant.total
        LP32161-9
        • Component Denominator Core
          Surfactant.total
          LP32161-9
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MFr
    LP6831-4
  • Time
    Pt
    LP6960-1
  • System
    Amnio fld
    LP7000-5
    • System Core
      Amnio fld
      LP7000-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
50009-0Fetal lung maturity panel - Amniotic fluid

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Sfingomyelin/surfaktant.celkový:Hmotnostní podíl:Časový bod:Amniová tekutina:Kvantitativní:
el-GRGreek (Greece)Σφιγγομυελινάση/Επιφανειοδραστική ουσία.ολική:MFr:Pt:Αμνιακό υγρό:Qn:
Synonyms: CHEM MFr Pt Qn Αμνιακό υγρό Επιφανειοδραστική ουσία Επιφανειοδραστική ουσία.ολική Σφιγγομυελινάση
es-ESSpanish (Spain)Esfingomielina/Surfactante.total:Fracción de masa:Punto temporal:Fluido Ammiótico:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Esfingomielina / Surfactante total:Fracción de masa:Punto temporal:Líquido amniótico:Cuantitativo:
et-EEEstonian (Estonia)Sfingomüeliin/surfaktant.üld:MFr:Pt:AmnF:Qn:
Synonyms: Amnionivedelik Juhuslik Kvantitatiivne Pindaktiivne aine
fr-CAFrench (Canada)Sphingomyéline/Surfactant.total:Fraction de masse:Temps ponctuel:Liquide amniotique:Quantitatif:
fr-FRFrench (France)Sphingomyéline/surfactant total:Fraction massique:Ponctuel:Liquide amniotique:Numérique:
fr-BEFrench (Belgium)Sphingomyéline/Surfactant.total:Fraction de masse:Temps ponctuel:Liquide amniotique:Quantitatif:
it-ITItalian (Italy)Sfingomielina/Surfattante totale:MFr:Pt:Liquido amniotico:Qn:
Synonyms: Chimica Frazione di massa Liquido amniotico Punto nel tempo (episodio) Tensioattivo
nl-NLDutch (Netherlands)sfingomyeline/surfactant.totaal:massafractie:moment:vruchtwater:kwantitatief:
pt-BRPortuguese (Brazil)Esfingomielina/Surfactante.total:MFr:Pt:LiqAmni:Qn:
Synonyms: Mass fraction; Percent; Point in time; Random; Amn; Amniotic fluid; Amn fl; Amniotic flu; AF; Quantitative; QNT; Quant; Quan; Tot; Totl; Chemistry
ru-RURussian (Russian Federation)Сфингомиелин/Сурфактант.общий:МассДол:ТчкВрм:Амниотич ждк:Колич:
Synonyms: Амниотическая жидкость Количественный Массовая доля Точка во времени;Момент
tr-TRTurkish (Turkey)Sfingomiyelin/Sürfaktan.total:KütlFr:Zmlı:Amniyon sv:Kant:
Synonyms: Amniyon mayii
zh-CNChinese (China)神经鞘磷脂/表面活性物质.总计:质量分数:时间点:羊水:定量型:
Synonyms: MFr 全体数量 全部 共计 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 总 总和 总数 总量 总额 时刻;随机;随意;瞬间 汇总 神经磷脂;神经鞘骨磷脂;鞘磷脂 羊膜水;胎水 表面活化剂;表面活化物质;表面活性剂 表面活性物质（表面活化剂、表面活化物质、表面活性物质）.总计（总、总和）;总表面活性物质（表面活化剂、表面活化物质、表面活性物质）

Example Units

UnitSource
%Example UCUM Units
%REGENSTRIEF

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49575-4