13741-4 Ethylmalonate/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP15563-7   Ethylmalonate
Ethylmalonic acid is identified in the urine of patients with short-chain acyl-coenzyme A dehydrogenase deficiency, which is a fatty acid metabolism disorder. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Ethylmalonic acid

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

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Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Ethylmalonate/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Ethylmalonate/Creat Ur

Display Name

Ethylmalonate/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Ethylmalonate/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Change Reason

This term was Discouraged in a previous release because at the time (2013), this analyte was not being measured in mass units. We are changing the term back to Active status because at least one major laboratory is currently (in 2018) measuring this analyte in mass units.

Order vs. Observation

Both

Common Test Rank Get Info

6880

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• EMA
• Ethylmalonic acid
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

13777-8 Methylsuccinate/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP18443-9   Methylsuccinate
Methylsuccinic acid is a normal metabolite found in human fluids. Increased urinary levels of Methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy [OMIM: 602473], a rare metabolic disorder with an autosomal recessive mode of inheritance that is clinically characterized by neuromotor delay, hyperlactic acidemia, recurrent petechiae, orthostatic acrocyanosis, and chronic diarrhea. PMID: 12382164 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Human Metabolome Database (Methylsuccinic acid)

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

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Type of Entry

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Fully-Specified Name

Component

Methylsuccinate/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Me-succinate/Creat Ur

Display Name

Methylsuccinate/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Methylsuccinate/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Change Reason

This term was Discouraged in a previous release because at the time (2013), this analyte was not being measured in mass units. We are changing the term back to Active status because at least two major laboratories are currently (in 2018) measuring this analyte in mass units.

Order vs. Observation

Both

Common Test Rank Get Info

6952

Member of these Panels

Language Variants Get Info

Related Names

• 2-Methylsuccinic acid
• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Me-succinate
• Methylsuccinic acid
• Point in time
• Pyrotartaric acid
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

13748-9 Glutarate/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP18437-1   Glutarate
Glutaric acid (IUPAC systematic name:pentanedioic acid) is a simple five-carbon linear dicarboxylic acid. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Glutarate (Wikipedia)

LP18437-1   Glutarate
Glutaric acid (glutarate) is a simple five-carbon linear dicarboxylic acid. The accumulation of glutaric acid ranging from slightly or intermittently elevated urinary glutaric acid to gross organic aciduria occurs in Glutaric aciduria. Glutaric aciduria type 1 is an autosomal-recessive disorder resulting from a deficiency of mitochondrial glutaryl-CoA dehydrogenase (EC 1.3.99.7, GCDH) which is involved in the metabolism of lysine, hydroxylysine, and tryptophan. Glutaric aciduria type I lead to nonspecific developmental delay, hypotonia, and macrocephaly with cerebral atrophy of prenatal onset. Treatment is mainly based on restriction of lysine intake, supplementation of carnitine, and an intensification of therapy during intercurrent illnesses. The major principle of dietary treatment is to reduce the production of glutaric acid and 3-hydroxyglutaric acid by restriction of natural protein in general and of lysine in particular. PMID: 17465389, PMID: 15505398 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

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Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Glutarate/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Glutarate/Creat Ur

Display Name

Glutarate/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Glutarate/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Change Reason

This term was Discouraged in a previous release because at the time (2013), this analyte was not being measured in mass units. We are changing the term back to Active status because at least two major laboratories are currently (in 2018) measuring this analyte in mass units.

Order vs. Observation

Both

Common Test Rank Get Info

7221

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Glutaric acid
• Mass concentration ratio
• Mass ratio
• MCRto
• Pentanedioiate
• Pentanedioic acid
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

38360-4 Isobutyrylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP14515-8   Isobutyrylglycine
Isobutyrylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine Isobutyrylglycine is identified in large amount in urine of patients with isobutyryl-CoA dehydrogenase deficiency. Isobutyryl-CoA dehydrogenase deficiency is a disorder caused by the deficiency of isobutyryl-CoA dehydrogenase that is involved in the catabolism of the branched-chain amino acid valine PMID: 15505379. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Isobutyrylglycine

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

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Type of Entry

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Fully-Specified Name

Component

Isobutyrylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Isobutyrylgly/Creat Ur

Display Name

Isobutyrylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Isobutyrylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.14

Last Updated

Version 2.73

Order vs. Observation

Observation

Common Test Rank Get Info

7176

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

27892-9 Butyrylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

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Type of Entry

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Fully-Specified Name

Component

Butyrylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Butyrylgly/Creat Ur

Display Name

Butyrylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Butyrylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.00

Last Updated

Version 2.73

Order vs. Observation

Observation

Common Test Rank Get Info

7210

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

27097-5 2-Methylbutyrylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP14511-7   2-Methylbutyrylglycine
2-Methylbutyrylglycine (2-MBG) is an acyl glycine generated by the L-isoleucine oxidation pathway. Increased levels of 2-MBG is a hallmark in short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD), an autosomal recessive inherited condition caused by a defect in isoleucine catabolism. PMID: 15615815 Source: Regenstrief LOINC, PMID: 15615815

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

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Type of Entry

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Fully-Specified Name

Component

2-Methylbutyrylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

2Me-butyrylglycine/Creat Ur

Display Name

2-Methylbutyrylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

2-Methylbutyrylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.00

Last Updated

Version 2.73

Order vs. Observation

Observation

Common Test Rank Get Info

7032

Member of these Panels

Language Variants Get Info

Related Names

• 2-MBG
• 2Me-butyrylglycine
• Chemistry
• CR
• Crea
• Creat
• II
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

13766-1 Isovalerylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP14516-6   Isovalerylglycine
Isovalerylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine Isovalerylglycine is a byproduct of the catabolism of the aminoacid leucine. Accumulation of isovalerylglycine occurs in Isovaleric Acidemia (IVA). IVA (OMIM/ McKusick 243500) is an autosomal recessive disorder caused by mutations in the isovaleryl-CoA dehydrogenase (EC 1.3.99.10) gene. The deficiency of this enzyme in the metabolism of leucine leads to the accumulation of a series of isovaleryl-CoA metabolites, such as isovalerylglycine (IVG). It is very important to caution for false positive results when screening for isovaleric acidemia by tandem mass spectrometry based on dried blood-spot levels of C5-acylcarnitines, including isovalerylcarnitine and its isomer, pivaloylcarnitine; pivaloylcarnitine is derived from pivalate-generating antibiotics, and has caused many false-positive results. PMID: 17850781. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Isovalerylglycine

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

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Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Isovalerylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Isovalerylgly/Creat Ur

Display Name

Isovalerylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Isovalerylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Change Reason

This term was Discouraged in a previous release because at the time (2013), this analyte was not being measured in mass units. We are changing the term back to Active status because at least two major laboratories are currently (in 2018) measuring this analyte in mass units.

Order vs. Observation

Observation

Common Test Rank Get Info

7222

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

13753-9 Hexanoylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP14514-1   Hexanoylglycine
Urinary hexanoylglycine is a specific marker for the diagnosis of Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. PMID: 3054550 Source: Regenstrief LOINC

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

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Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Hexanoylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Hexanoylgly/Creat Ur

Display Name

Hexanoylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Hexanoylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

7206

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Hexanoyl-glycine
• Mass concentration ratio
• Mass ratio
• MCRto
• N-caproylglycine
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

99059-8 N-acetylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

n-Acetylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

N-acetylglycine/Creat Ur

Display Name

N-acetylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

N-acetylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.72

Last Updated

Version 2.72

Order vs. Observation

Observation

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

38367-9 N-octanoylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

N-octanoylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

n-octanoylgly/Creat Ur

Display Name

N-octanoylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

N-octanoylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.14

Last Updated

Version 2.73

Order vs. Observation

Observation

Common Test Rank Get Info

7209

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

13793-5 Phenylpropionylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP14517-4   Phenylpropionylglycine
Phenylpropionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13), which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The detection of phenylpropionylglycine in urine after an oral load of phenylpropionic acid can be used to diagnose deficiency of medium-chain acyl-CoA dehydrogenase, a frequent and treatable metabolic defect. PMID: 9234867 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Phenylpropionylglycine

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Phenylpropionylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

PPG/Creat Ur

Display Name

Phenylpropionylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Phenylpropionylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Change Reason

This term was Discouraged in a previous release because at the time (2013), this analyte was not being measured in mass units. We are changing the term back to Active status because at least two major laboratories are currently (in 2018) measuring this analyte in mass units.

Order vs. Observation

Both

Common Test Rank Get Info

7218

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• PPG
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

13811-5 Suberylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP14519-0   Suberylglycine
Suberylglycine is a dicarboxylic acid. It is formed by glycine-N-acylase catalyzed conjugation. PMID: 947635 It can be used for the diagnosis of hereditary medium-chain acyl-CoA dehydrogenase deficiency. PMID: 2775902 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Suberylglycine

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Suberylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Suberylgly/Creat Ur

Display Name

Suberylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Suberylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Change Reason

This term was Discouraged in a previous release because at the time (2013), this analyte was not being measured in mass units. We are changing the term back to Active status because at least two major laboratories are currently (in 2018) measuring this analyte in mass units.

Order vs. Observation

Observation

Common Test Rank Get Info

7234

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

38417-2 Trans-cinnamoylglycine/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Trans-cinnamoylglycine/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

tr-Cinnamoylgly/Creat Ur

Display Name

Trans-cinnamoylglycine/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Trans-cinnamoylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.14

Last Updated

Version 2.73

Order vs. Observation

Observation

Common Test Rank Get Info

7208

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• tr-Cinnamoylgly
• UA
• UCr
• UR
• Urn

Example Units

13732-3 Dodecanedioate/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP18434-8   Dodecanedioate
Dodecanedioic acid is a dicarboxylic acid mainly used in antiseptics, top-grade coatings, painting materials, corrosion inhibitor, surfactant, and engineering plastics. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Dodecanedioate/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

DDDA/Creat Ur

Display Name

Dodecanedioate/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Dodecanedioate/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Order vs. Observation

Observation

Common Test Rank Get Info

7207

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• DDDA
• Dodecanedioic acid
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

50333-4 Tetradecanedioate/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Tetradecanedioate/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Tdecanedioate/Creat Ur

Display Name

Tetradecanedioate/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Tetradecanedioate/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.22

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

7052

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Tdecanedioate
• UA
• UCr
• UR
• Urn

Example Units

50332-6 Hexadecanedioate/Creatinine [Mass Ratio] in Urine

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component

Hexadecanedioate/Creatinine

Property

MRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Hexadecanedioate/Creat Ur

Display Name

Hexadecanedioate/Creatinine (U) [Mass ratio]

Consumer Name Alpha Get Info

Hexadecanedioate/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.22

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

9491

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Hexadecanedioic acid
• Mass concentration ratio
• Mass ratio
• MCRto
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UA
• UCr
• UR
• Urn

Example Units

53718-3 Acylglycines [Interpretation] in Urine Narrative

Observation Required in Panel

Optional

Fully-Specified Name

Component

Acylglycines

Property

Imp

Time

Pt

System

Urine

Scale

Nar

Method

Additional Names

Short Name

Acylglycines Ur-Imp

Display Name

Acylglycines Nar (U) [Interp]

Consumer Name Alpha Get Info

Interpretation of Acylglycines test result, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.26

Last Updated

Version 2.73

Order vs. Observation

Observation

Common Test Rank Get Info

11280

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• Impression
• Impression/interpretation of study
• Impressions
• Interp
• Interpretation
• Narrative
• Point in time
• Random
• Report
• UA
• UR
• Urn