Version 2.78

Part Description

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A Ab
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method
Comp fix

Additional Names

Short Name
FLUAV Ab Titr Ser CF
Display Name
FLUAV Ab CF (S) [Titer]
Consumer Name Alpha Get Info
Influenza A (Flu A) antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.75
Order vs. Observation
Both
Common Test Rank Get Info
7560

Member of these Groups Get Info

LOINC Group Group Name
LG32757-3 Influenza virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Influenza-Virus A Ak:Titer:Zeitpunkt:Serum:Semiquantitativ:Komplementbindungsreaktion
es-AR Spanish (Argentina) [anticuerpo anti - ] virus influenza A [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:fijación del complemento
es-ES Spanish (Spain) Virus Influenza A Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Fijación del complemento
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Virus de la influenza A Ab:Título:Punto temporal:Suero:Cuantitativo:Fijación del complemento
fr-CA French (Canada) Virus de l'influenza A, Ac:Titre:Temps ponctuel:Sérum:SemiQn:Fixation du complément
fr-FR French (France) Influenza virus A Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:Fixation du complément
it-IT Italian (Italy) Influenza A, virus Ab:Titr:Pt:Siero:SemiQn:Fissazione complemento
Synonyms: anticorpo Fissazione del complemento Microbiologia Punto nel tempo (episodio) Siero Titolo Virus dell''influenza Virus dell''influenza A
ko-KR Korean (Korea, Republic Of) A형 인플루엔자 바이러스 항체:역가:검사시점:혈청:정량:보체결합반응
nl-NL Dutch (Netherlands) Influenzavirus A As:titer:moment:serum:semikwantitatief:complementfixatie
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Wirus grypy A Ab:miano:punkt w czasie:surowica:półilościowy:test wiązania dopełniacza
Synonyms: Przeciwciała do wirusa grypy typ A Wirus grypy Wirus grypy typ A
pt-BR Portuguese (Brazil) Influenza vírus A Ac:Título:Pt:Soro:Qn:Fixação do complemento
Synonyms: ; FLUAV; Avian influenza; Fowl plague; Influenza A virus; FLUA; Bird flu; FLUV; Influ; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; CF; Complement fixation; Compfix; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN Chinese (China) 流感病毒 A 型 抗体:滴定度:时间点:血清:半定量型:补体结合试验
Synonyms: A 型 A 型抗体 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 A 型流感病毒 Ab A 型流感病毒抗体 Ab;自身抗体 FLUA Ab FLUA 抗体 FLUAV Ab FLUAV 抗体 FLUV;Influ;列性感冒病毒;流行性感冒病毒 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 流感病毒 A 型 Ab 流感病毒甲型 Ab 流感病毒甲型抗体 甲型流感病毒 Ab 甲型流感病毒抗体 补体固定;补体固定试验;补体结合;补体结合反应

Example Units

Unit Source
titer REGENSTRIEF
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5229-0